Histology News and Research

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Researchers create large-scale 2D and 3D spatial maps of colorectal cancer

In the United States, turning 45 brings with it a rather unpleasant rite of passage: the beginning of regular colonoscopies, in which an endoscope equipped with a light and a camera is used to visually check the colon for signs of cancer.

19 Jan 2023

Advanced MRI tool can reveal new structural insights into atherothrombosis

Atherosclerosis is a long-term arterial vessel wall disease characterized by the build- up of lipid- rich and inflamed plaques.

3 Jan 2023

New ASTRO guideline provides recommendations on the use of radiation therapy for endometrial cancer

A newly updated clinical guideline from the American Society for Radiation Oncology provides recommendations on the use of radiation therapy and systemic therapy after surgery to treat patients with endometrial cancer.

7 Dec 2022

The effect of ubiquitination on SARS-CoV-2 infection and patient prognosis

A recent Clinical and Translational Medicine study utilized several published public datasets to evaluate the biological characteristics associated with the ubiquitination of patients infected with SARS-CoV-2.

2 Dec 2022

Powerful imaging tool creates 3D atlas of the spectrum of tuberculous and COVID-19 lung lesions

Gross anatomy reveals three-dimensional shapes of pathology at a large scale. Histology, in contrast, reveals the microscopic anatomy of biological structures. But that magnification comes at a cost -; histology shows only two-dimensional shapes because it studies small, flat slices of stained tissue.

29 Nov 2022

Photon-counting CT may help to effectively identify post-COVID patients at risk for lung damage

New CT technology outperforms conventional CT in detecting subtle damage in the lungs of patients with persistent symptoms of COVID-19, according to a new study published in Radiology, a journal of the Radiological Society of North America.

29 Nov 2022

Researchers develop a new method to map the spatial evolution of cancers

Researchers developed a genetic clone mapping workflow centered around base-specific in situ sequencing (BaSISS) technology to derive quantitative maps of multiple genetic clones of cancer cells.

11 Nov 2022

Study identifies a root cause of chronic heart failure following a heart attack

A multi-institution study led by Rohan Dharmakumar, PhD, of Indiana University School of Medicine, has identified that iron drives the formation of fatty tissue in the heart and leads to chronic heart failure in about fifty percent of heart attack survivors.

1 Nov 2022

First preclinical model to study the pathobiology of appendiceal cancer

Appendiceal cancer (malignancies of the appendix, a small tissue pouch that is part of the gastrointestinal tract) is very rare, occurring in perhaps one or two people per 1 million per year.

1 Nov 2022

Researchers use deep neural networks to virtually stain microscopic images of unlabeled tissue

In the hospital, there is a group of doctors who use tissue samples as "evidence materials", analyze the evidence using knives, slicers and microscopes to extract clues from the tissue samples, and provide patients with "verdicts" -; diagnostic reports.

31 Oct 2022

Research reveals molecular pathways of aggressive cribriform prostate cancer

Cribriform prostate cancer is an aggressive subtype of the disease characterized by its histology, but little is known about its molecular pathways.

26 Oct 2022

AI model predicts the likelihood of unplanned hospitalization during radiation treatments for cancer

An artificial intelligence (AI) model developed by researchers can predict the likelihood that a patient may have an unplanned hospitalization during their radiation treatments for cancer.

24 Oct 2022

New partnership creates an automated anatomic pathology slide-scanning solution

Sakura Finetek, a global leader in histopathology products and Evident Scientific, a wholly owned subsidiary of Olympus Corporation, and a global leader in microscopy and imaging solutions, today announced a collaboration to offer a full workflow solution for anatomic pathology slide preparation and high-resolution digital scanning in the Americas.

From Evident Corporation - Life Sciences 13 Oct 2022

Self-teaching deep learning algorithm can find similar cases in large pathology image repositories

Rare diseases are often difficult to diagnose and predicting the best course of treatment can be challenging for clinicians.

10 Oct 2022

Chronic liver disease in COVID-19 patients

A recent study summarizes the clinical outcomes of COVID-19 patients with chronic liver disease.

10 Oct 2022

What is the impact of monkeypox infection on the hemostatic system?

In a recent study, researchers determined if monkeypox (MPX) infection affected the hemostatic system like that observed in coronavirus disease 2019 (COVID-19).

6 Oct 2022

Excessive smartphone use may lead to early puberty

Exposure to blue light via regular use of tablets and smartphones may alter hormone levels and increase the risk of earlier puberty, according to data from a rat study presented today at the 60th Annual European Society for Paediatric Endocrinology Meeting.

16 Sep 2022