Ibuprofen News and Research

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Ibuprofen is a drug used to treat fever, swelling, pain, and redness by preventing the body from making a substance that causes inflammation. It is a type of nonsteroidal anti-inflammatory drug (NSAID). Ibuprofen is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic effects. Ibuprofen inhibits the activity of cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. This leads to decreased prostaglandin synthesis, by prostaglandin synthase, the main physiologic effect of ibuprofen. Ibuprofen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation.

Introducing deuterium makes drugs to have a longer effect

Hydrogen (abbreviated "H") is the lightest of all elements. It usually consists only of a positively charged proton and a negatively charged electron and is also called protium in this form. But there are also two heavier hydrogen isotopes, deuterium and tritium.

24 Dec 2021

Febrile seizures in children: Key things to know

When a child has a fever, their body can ache, they are restless and they just don't feel well. While a fever is a part of our natural response to infection, the fever itself can lead to complications. One rare complication is a febrile seizure.

3 Dec 2021

Study shows risk of MIS-C post mRNA vaccination against COVID-19 in children with autoimmune complications

Researchers discuss two cases of MIS-V after the patients had received the SARS-CoV-2 vaccine from Pfizer/BioNTech (BNT162b2).

23 Nov 2021

Oral acetaminophen helps manage tonsillectomy pain in children at lower costs

Providing children oral instead of intravenous (IV) acetaminophen to help manage tonsillectomy pain improves care at lower costs, according to research being presented at the ANESTHESIOLOGY® 2021 annual meeting.

11 Oct 2021

Novel scoring tools developed for predicting risk of colon cancer and precancerous polyps

Researchers have created novel scoring tools for predicting actual risk of colon cancer and advanced precancerous polyps for patients at average for the disease.

5 Oct 2021

Limited options for managing UTIs make women fearful and frustrated

Despite the prevalence of the painful condition, women are fearful and frustrated with limited management options, according to Cedars-Sinai research published in the Journal of Urology.

2 Oct 2021

Children and young adults are frequently exposed to unsafe opioid prescriptions, study suggests

Children and young adults who have pain from surgery, dental care and other conditions are often prescribed opioids.

19 Aug 2021

Popular painkillers can be used as personal dosimeters in a radiation emergency

When proper precautions are taken, radioactive substances are extremely safe to use. But what if they leak into the environment in an uncontrolled manner? Then it becomes crucial to find out the dose of radiation people may have absorbed.

12 Aug 2021

Not all experts are ready to vaccinate kids against Covid

Lucien Wiggins, 12, arrived at Tufts Children's Hospital by ambulance June 7 with chest pains, dizziness and high levels of a protein in his blood that indicated inflammation of his heart. The symptoms had begun a day earlier, the morning after his second vaccination with the Pfizer-BioNTech mRNA shot.

17 Jun 2021

Surgeons can avoid postoperative opioid prescriptions, studies suggest

Surgeons can ease their patients' pain from common operations without prescribing opioids, and avoid the possibility of starting someone on a path to long-term use, a pair of new studies suggests.

10 Jun 2021

Chemical engineers devise a simpler process to incorporate hydrophobic drugs into tablets

About 60 percent of drugs on the market have hydrophobic molecules as their active ingredients. These drugs, which are not soluble in water, can be difficult to formulate into tablets because they need to be broken down into very small crystals in order to be absorbed by the human body.

8 Jun 2021

Scientists propose new strategies to find drugs that neutralize critical enzymes

Scientists from the University of Bath explore racemases and propose strategies for finding drugs that target these important enzymes.

26 May 2021

Are COVID-19 medications safe in pregnancy?

Most medications being tested today in clinical trials for the treatment of coronavirus disease 2019 (COVID-19) have been repurposed from other indications. These are typically not tested in pregnant women. A new study, published in the journal PLOS ONE, summarizes what is known about the safety of these drugs in this group.

24 May 2021

New peptides allow cannabis-derived drugs to fight pain in mice without side effects

An international team, led by researchers from Pompeu Fabra University (UPF) in Barcelona, Spain, David Andreu and Rafael Maldonado, has developed a peptides family that allows delta-9-tetrahydrocannabinol (THC), the main component of Cannabis sativa, to fight pain in mice without side effects.

20 May 2021

Many adults with hypertension may be taking other medications that could raise blood pressure

Nearly 1 in 5 adults with high blood pressure, a leading risk factor for heart disease and stroke, also take a medicine that could be elevating their blood pressure, according to new research presented at the American College of Cardiology's 70th Annual Scientific Session.

6 May 2021

Study finds higher risk of overdose in patients treated with opioids to reduce dental pain

When they go to the dentist to get a tooth pulled or another procedure, patients might not think that the prescription they receive to ease their pain could put them or their family at risk of an opioid overdose.

29 Apr 2021

Some COX inhibitors/NSAIDs increase COVID-19 severity

A startling new preprint research paper posted to the medRxiv server warns against the use of commonly used non-steroidal anti-inflammatory drugs (NSAIDs) belonging to the category of cyclooxygenase inhibitors (COX inhibitors) in patients with coronavirus disease 2019 (COVID-19).

22 Apr 2021

Long-term, regular use of baby aspirin may reduce risk of colorectal cancer death

Long-term, regular use of baby aspirin-;at least 15 times per month-;prior to a diagnosis of colorectal cancer (CRC) may reduce the risk of death from the disease by limiting the spread of cancerous tumors pre-diagnosis, according to a study led by Cedars-Sinai Cancer researchers.

29 Mar 2021

Antidepressants provide no important benefits for managing low back pain

A new systematic review led by UNSW Sydney has found that treating low back pain with antidepressant medicines provides no important benefits and has the potential to cause harm.

8 Mar 2021

Post-surgery opioid prescribing guideline leads to high patient satisfaction with pain management

A prescribing guideline tailored to patients' specific needs reduced the number of opioid pills prescribed after major surgery with researchers reporting a greater than 90 percent patient satisfaction rate with pain management and the highest compliance rate to date with appropriate disposal of leftover pills.

25 Feb 2021