Ibuprofen News and Research

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Ibuprofen is a drug used to treat fever, swelling, pain, and redness by preventing the body from making a substance that causes inflammation. It is a type of nonsteroidal anti-inflammatory drug (NSAID). Ibuprofen is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic effects. Ibuprofen inhibits the activity of cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. This leads to decreased prostaglandin synthesis, by prostaglandin synthase, the main physiologic effect of ibuprofen. Ibuprofen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation.

Low-cost intervention could easily be used to right-size opioid prescribing after surgery

A small tweak to hospitals' prescribing systems might make a big difference in reducing risk from leftover opioid pain medication, while still making sure surgery patients get relief from their post-operation pain, a new study suggests.

30 Jun 2022

What you need to know about monkeypox

The World Health Organization said June 25 that monkeypox wasn't yet a public health emergency of international concern. More than 4,500 cases have been reported worldwide, with more than 300 in the U.S. And with public health officials unable to follow all chains of transmission, they're likely undercounting cases.

29 Jun 2022

Researchers assess the evidence basis for medications used to treat spine-related pain in older adults

Spine-related pain is increasingly common in older adults. While medications play an important role in pain management, their use has limitations in geriatric patients due to reduced liver and kidney function, comorbid medical problems and polypharmacy (the simultaneous use of multiple drugs to treat medical conditions).

28 Jun 2022

Combination of certain drugs along with ibuprofen can cause acute kidney injury

Anyone who is taking a diuretic and a renin-angiotensin system (RSA) inhibitor for high blood pressure should be cautious about also taking ibuprofen, according to new research.

5 May 2022

Study assesses whether early targeted treatment of patent ductus arteriosus improves outcomes in extreme preterm babies

A randomized controlled trial evaluates if selective early treatment of patent ductus arteriosus reduces death or bronchopulmonary dysplasia at 36 weeks in extreme preterm babies.

22 Apr 2022

Patients’ perilous months-long waiting for Medicaid coverage is a sign of what’s to come

Korra Elliott has tried to avoid seeing a doctor while waiting to get on Medicaid. She worries she can't afford more bills without any insurance coverage. But in early March — five months, she said, after applying and with still no decision about her application — a suspected case of the flu sent her blood pressure soaring and landed her in the emergency room.

4 Apr 2022

The effects of anti-SARS-CoV-2 monoclonal antibodies on pregnant and postpartum women

Researchers examine the safety and efficacy of mAbs in pregnant and postpartum women with COVID-19.

16 Mar 2022

Drug misuse is not exclusive to the opioid epidemic, suggests study

Drug misuse is not exclusive to the opioid epidemic, according to a recent West Virginia University study. Every year, about 50,000 people in the United States are admitted to the emergency room due to misuse of a common over-the-counter pain medication – acetaminophen.

2 Mar 2022

Scientists use entire human GI tracts to shed light on cellular functions

If you get nervous, you might feel it in your gut. If you eat chili, your gut might revolt, but your friend can eat anything and feel great. You can pop ibuprofen like candy with no ill effects, but your friend's belly might bleed and she might get no pain relief.

21 Feb 2022

Oral penicillin may be a safer option for people with high-risk rheumatic heart disease

A growing body of evidence indicates that some people thought to have an allergic response to injectable penicillin, the standard treatment for rheumatic heart disease, may instead be experiencing a cardiac reaction to the medicine, according to a new American Heart Association presidential advisory published today in Journal of the American Heart Association.

19 Jan 2022

Introducing deuterium makes drugs to have a longer effect

Hydrogen (abbreviated "H") is the lightest of all elements. It usually consists only of a positively charged proton and a negatively charged electron and is also called protium in this form. But there are also two heavier hydrogen isotopes, deuterium and tritium.

24 Dec 2021

Febrile seizures in children: Key things to know

When a child has a fever, their body can ache, they are restless and they just don't feel well. While a fever is a part of our natural response to infection, the fever itself can lead to complications. One rare complication is a febrile seizure.

3 Dec 2021

Study shows risk of MIS-C post mRNA vaccination against COVID-19 in children with autoimmune complications

Researchers discuss two cases of MIS-V after the patients had received the SARS-CoV-2 vaccine from Pfizer/BioNTech (BNT162b2).

23 Nov 2021

Oral acetaminophen helps manage tonsillectomy pain in children at lower costs

Providing children oral instead of intravenous (IV) acetaminophen to help manage tonsillectomy pain improves care at lower costs, according to research being presented at the ANESTHESIOLOGY® 2021 annual meeting.

11 Oct 2021

Novel scoring tools developed for predicting risk of colon cancer and precancerous polyps

Researchers have created novel scoring tools for predicting actual risk of colon cancer and advanced precancerous polyps for patients at average for the disease.

5 Oct 2021

Limited options for managing UTIs make women fearful and frustrated

Despite the prevalence of the painful condition, women are fearful and frustrated with limited management options, according to Cedars-Sinai research published in the Journal of Urology.

2 Oct 2021

Children and young adults are frequently exposed to unsafe opioid prescriptions, study suggests

Children and young adults who have pain from surgery, dental care and other conditions are often prescribed opioids.

19 Aug 2021

Popular painkillers can be used as personal dosimeters in a radiation emergency

When proper precautions are taken, radioactive substances are extremely safe to use. But what if they leak into the environment in an uncontrolled manner? Then it becomes crucial to find out the dose of radiation people may have absorbed.

12 Aug 2021

Not all experts are ready to vaccinate kids against Covid

Lucien Wiggins, 12, arrived at Tufts Children's Hospital by ambulance June 7 with chest pains, dizziness and high levels of a protein in his blood that indicated inflammation of his heart. The symptoms had begun a day earlier, the morning after his second vaccination with the Pfizer-BioNTech mRNA shot.

17 Jun 2021

Surgeons can avoid postoperative opioid prescriptions, studies suggest

Surgeons can ease their patients' pain from common operations without prescribing opioids, and avoid the possibility of starting someone on a path to long-term use, a pair of new studies suggests.

10 Jun 2021