Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Research identifies how insulin-producing islet cells from pigs may cure diabetes

Within three years, insulin-producing islet cells from pigs may be used in clinical trials on a path to finally cure insulin dependant diabetes.

13 Sep 2007

Mutations in the insulin gene can cause permanent neonatal diabetes

Mutations in the insulin gene can cause permanent neonatal diabetes, an unusual form of diabetes that affects very young children and results in lifelong dependence on insulin injections, report researchers from the University of Chicago and Peninsula University (Exeter, UK) in Sept. 18, 2007, issue of the Proceedings of the National Academy of Sciences, published early online.

11 Sep 2007

Metformin could potentially improve pregnancy outcomes in women with insulin resistance

Women who are obese, have type 2 diabetes or a family history of type 2 diabetes could one day have more successful pregnancies because of a study at Washington University School of Medicine in St. Louis.

10 Sep 2007

Antiobesity gene

Researchers have revealed an antiobesity gene that has apparently been keeping critters lean during times of plenty since ancient times.

5 Sep 2007

Adipose gene may be the key to tackle weight

Researchers at UT Southwestern Medical Center have found that a single gene might control whether or not individuals tend to pile on fat, a discovery that may point to new ways to fight obesity and diabetes.

5 Sep 2007

Fatty hearts in pre-diabetics

A simple imaging technique developed by UT Southwestern Medical Center researchers has revealed fat buildup in the hearts of pre-diabetic people long before symptoms of heart disease or diabetes appear.

5 Sep 2007

Immunosuppressive drugs are a double-edged sword to type 1 diabetics

Type 1 diabetes is caused when immune cells attack and destroy the insulin producing beta-cells of the pancreas.

5 Sep 2007

New way to burn off calories

A new study in the September issue of Cell Metabolism, a publication of Cell Press, points to a new method for burning off all those irresistible extra calories—by turning on an energy-draining, but otherwise futile, cycle of protein synthesis and breakdown.

5 Sep 2007

Role of self monitoring in patients with type 2 diabetes

A new study published on bmj.com calls for better advice about home blood glucose monitoring for patients with non-insulin dependent (type 2) diabetes.Type 2 diabetes usually develops in people over 40, especially when the person is overweight.

3 Sep 2007

Insights into the physiological basis of obesity

The past decade has witnessed an explosion of information regarding the role of the central nervous system (CNS) in the development of obesity and the influence of peripheral, hormonal signals that regulate CNS function to regulate food intake and metabolism.

3 Sep 2007

The burden of diabetes in heart disease in Europe

Diabetes is becoming one of the major health problems in the European and US populations. It is frequently associated with overweight, hypertension and high serum cholesterol levels, representing a dangerous combination of risk factors for the development of heart and vascular diseases.

2 Sep 2007

Are there gender differences in management modalities?

There are major differences in the risk profile and characteristics of female patients treated for acute heart failure. Female patients are underrepresented in management trials on Heart Failure. According to data from the Euro Heart Survey on acute Heart Failure 2004-2005 in Europe, however, medical treatment has improved.

2 Sep 2007

FDA approves Somatuline Depot to treat acromegaly

The U.S. Food and Drug Administration has approved Somatuline Depot (lanreotide acetate injection) for the treatment of acromegaly, a rare and potentially life threatening disease in adults caused by abnormal secretion of growth hormone (GH), commonly from a benign tumor located in the pituitary gland located in the brain.

30 Aug 2007

Discovery may lead to new class of diabetes drugs

A multidisciplinary team led by researchers at the University of California, San Diego has determined the structure of a protein found in cells that shows potential as a target for the development of new drugs to treat diabetes.

30 Aug 2007

Brain's impaired ability to sense glucose might play role in type 2 diabetes

New findings from studies in mice suggest that defects in the brain's ability to respond to glucose play a role in the development of non-insulin dependent (type 2) diabetes, and that a high-fat diet may contribute to impairing brain cells' ability to regulate glucose throughout the body.

30 Aug 2007