Leptin News and Research

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Leptin is a 16 kDa protein hormone that plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism. It is one of the most important adipose derived hormones. The ''Ob(Lep)'' gene (Ob for obese, Lep for leptin) is located on chromosome 7 in humans.

Overweight adolescents actually eat less when exposed to stressful events

People often react to stress by binging on sweets or fattening comfort foods, cravings fueled by the appetite-stimulating stress hormone cortisol.

3 Sep 2019

Maternal high-fat diet may slow learning ability in offspring, study suggests

In a bid to further explore how a mother-to-be's diet might affect her offspring's brain health, Johns Hopkins Medicine researchers have found that pregnant and nursing rats fed high fat diets have offspring that grow up to be slower than expected learners and that have persistently abnormal levels of the components needed for healthy brain development and metabolism.

From Johns Hopkins Medicine 28 Aug 2019

Intermittent fasting may regulate blood glucose levels even without weight loss

New research suggests that intermittent fasting, cycling through periods of normal eating and fasting may regulate blood sugar (glucose) levels even when accompanied by little-to-no weight loss.

17 Jul 2019

Metabolic enzyme tied to obesity and fatty liver disease

A team of researchers at the Clemson University found that Cyp2b gene, which metabolizes endo and xenobiotics, may be linked to age-onset obesity and dyslipidemia, especially in males.

11 Jul 2019

Maternal obesity may negatively affect children's lung development

Obesity during pregnancy may negatively affect children's lung development, according to new research. The study, published ahead of print in the American Journal of Physiology-;Lung Cellular and Molecular Physiology, was chosen as an APSselect article for July.

2 Jul 2019

New mutation discovered in the leptin gene

The global obesity epidemic is so far-reaching it now has an overarching name: globesity. Texas Biomed Staff Scientist Raul Bastarrachea, M.D., is part of a team that discovered a new mutation in the gene that regulates the key hormone suppressing hunger called leptin.

22 Jun 2019

New findings offer pathway for fight against non-alcoholic fatty liver disease

A research group from the Medical University of Vienna was able to decode the mechanism as to how the hormone Leptin stimulates the liver to export lipids and reduce the fat production in the liver.

21 Jun 2019

Yale researchers offer insight into the hunger hormone

In a new study, Yale researchers offer insight into leptin, a hormone that plays a key role in appetite, overeating, and obesity. Their findings advance knowledge about leptin and weight gain, and also suggest a potential strategy for developing future weight-loss treatments, they said.

19 Jun 2019

The basal forebrain may hold clues to food avoidance behavior

After fasting for 24 hours the typical laboratory mouse spends much time eating. Surprisingly, this is not what Jay M. Patel saw when he was studying basal forebrain circuits in mice.

18 Jun 2019

Women's pre-pregnancy obesity changes breast milk contents which can affect infant growth

In the first study of its kind, LSU Health New Orleans researchers report that women's pre-pregnancy overweight or obesity produces changes in breast milk, which can affect infant growth.

14 Jun 2019

Pre-pregnancy maternal obesity may affect growth of breastfeeding infants

A pioneering new study suggests that babies born to obese or overweight women fail to grow properly during breastfeeding.

14 Jun 2019

Obesity linked with greater symptomatic severity of multiple sclerosis

Obesity is an aggravating factor in relapsing-remitting multiple sclerosis, the most common form of the disease.

6 Jun 2019

Growth hormone acts directly on the brain to conserve energy when the body loses weight

Researchers at the University of São Paulo in Brazil have discovered that growth hormone (GH), which stimulates skeletal maturation and linear bone growth, as well as helping maintain tissue and organs throughout life, also acts directly on the brain to conserve energy when the body loses weight.

12 Apr 2019

Eat intuitively, not restrictively

Listening to the body's cues and acting on these cues, instead of ignoring them, may improve diet success, according to researchers.

5 Apr 2019

Researchers explore biological mechanisms behind obesity-cancer link

New studies led by University of North Carolina Lineberger Comprehensive Cancer Center researchers explore biological mechanisms behind obesity and its link with cancer.

1 Apr 2019

Scientists identify genetic mechanism that may play role in some obesity cases

Obesity is a major public-health problem in the United States and around the world, with an estimated 650 million people suffering from the condition.

7 Mar 2019

The role of galanin-like peptide in regulating feeding behavior and energy metabolism

Galanin-like peptide is a short peptide made up of 60 amino acid residues. This sequence is homologous across several species. The hypothalamic arcuate nucleus is the place where GALP is produced. GALP has diverse physiological effects such as the regulation of feeding, energy metabolism, and reproductive behavior.

25 Dec 2018

Air pollution linked with development of Alzheimer's in Mexico City children

A new study by researchers at the Universities of Montana, Valle de México, Boise State, Universidad Veracruzana, Instituto Nacional de Pediatría and Paul-Flechsig-Institute for Brain Research heightens together with German company Analytik Jena concerns over the evolving and relentless Alzheimer's pathology observed in young Metropolitan Mexico City urbanites.

21 Dec 2018

Single workout can improve metabolism for up to 2 days

Lounging around all weekend may weigh heavy on the minds of the health conscious. But these sedentary stretches may not affect the waistline, provided they're preceded by a bit of exercise.

4 Dec 2018

Experts debate over whether gut or brain is more important in regulating appetite

Whether gut or brain hormones are more important for the regulation of appetite and metabolism is not clearly defined. Imbalances in the control of appetite and metabolism can lead to obesity and diabetes, which have a negative impact on people's health and healthcare costs.

19 Nov 2018