Leukocyte News and Research

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Survival mechanism of T lymphocytes uncovered

When an individual is challenged by a virus, a bacterium or any other infectious agent, several classes of white blood cells are being activated in order to fight the invasion.

19 Mar 2008

New interventional radiology treatment shows promise for complications from bone marrow, stem cell tranplants

The standard treatment to treat graft-versus-host disease (GVHD) after bone marrow or cord blood transplant is intravenous (IV) steroids that alter the immune response; however, it is not always effective and failure results in very high mortality.

19 Mar 2008

Do bacterial combinations result in enhanced cytokine production? No!

Probiotic bacteria, defined as living microorganisms that have beneficial effects on human health, have been used for the prevention and treatment of a diverse range of disorders.

19 Mar 2008

Discovery alters long standing concept of fixed protein structure

The thousands of proteins found in nature are simply strings of amino acids, assembled by genes, and scientists have long believed that they automatically fold themselves into uniquely fixed, 3-dimensional shapes to fire the engine of life.

19 Mar 2008

New understanding of rare immune disorder called Job's syndrome

Scientists have made another major breakthrough--the second in the past year--in understanding a rare immune disorder called Job's syndrome.

18 Mar 2008

New discovery alters longstanding concept of fixed protein structure

18 Mar 2008

Finding in mice could help prevent common complications of kidney damage

Kidney damage often sets off a slew of complications in patients, spreading organ failure like wildfire throughout their bodies.

14 Mar 2008

Turning off rogue macrophages

University of Pennsylvania scientists studying macrophages, the biological cells that spring from white blood cells to eat and destroy foreign or dying cells, have discovered how these "policemen" differentiate between friend and foe.

12 Mar 2008

Predictors for sickle-cell-anemia complications

Researchers at UT Southwestern Medical Center have determined that the level, or saturation, of oxygen in blood could be used to identify children with sickle cell anemia who are at an increased risk of stroke.

6 Mar 2008

Watery pools in bone marrow key to psoriatic arthritic damage

Researchers have learned more about how a leading drug prevents certain types of arthritis from eating away at bone, according to a study published in the March edition of the Annals of the Rheumatic Diseases.

4 Mar 2008

Researchers investigate predictors for sickle-cell-anemia complications

1 Mar 2008

Statistical modeling improves quality of laboratory data

Many areas of research and medicine rely critically upon knowing a person's individual immune system proteins, as they determine an individual's ability to fight disease or mistakenly attack their own tissues.

1 Mar 2008

AstraZeneca submits sNDA for SEROQUEL XR for treatment of major depressive disorder

AstraZeneca has announced the submission of a supplemental New Drug Application (sNDA) to the U.S. Food and Drug Administration (FDA) for once- daily SEROQUEL XR (quetiapine fumarate) Extended-Release Tablets to seek approval for the treatment of major depressive disorder (MDD) as monotherapy, adjunct therapy, and maintenance therapy in adult patients.

1 Mar 2008