Liquid Chromatography News and Research

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Novel ingestible device enables non-invasive profiling of the gut microbiome, proteome, and metabolome

Researchers developed an ingestible device to collect samples from the human intestine.

12 May 2023

A machine-learning approach for the early diagnosis of Parkinson's disease

Scientists discuss a machine learning-based tool that can detect Parkinson's disease years before the first onset of symptoms.

11 May 2023

Laboratory instrument manufacturer from berlin honored with vorsprung award at the chancellor's office

On May 9, 2023, the VORSPRUNG Business Award, an accolade of the East German Business Forum OWF, was presented in Berlin at the Federal Chancellery.

From KNAUER Wissenschaftliche Geräte GmbH 11 May 2023

High-fat diets' eye-opening impact: Study reveals link to retinal damage and bisretinoid accumulation

In this study, the effects of a high-fat diet on the formation of bisretinoids in photoreceptor cells were explored. The results showed that mice on a high-fat diet had increased levels of bisretinoids and retinol-binding protein 4, which are associated with metabolic dysregulation.

8 May 2023

The dynamics and interactions between the skin metabolome, microbiome, and UV exposure

Researchers evaluated metabolic profile changes of the skin in relation to microbiota and UV exposure.

5 May 2023

Evaluating the association between Mediterranean Diet adherence and type 2 diabetes using nutritional biomarkers

Researchers developed a method for objective assessment of the effect Mediterranean Diet on T2D.

1 May 2023

Uncovering the interplay between (poly)phenol intake and cardiometabolic health

Researchers aimed to understand the relationship between (poly)phenol consumption and cardiometabolic health.

28 Apr 2023

Low vitamin D levels during pregnancy linked to childhood obesity in boys

Study examines the association between prenatal vitamin D levels and growth and adiposity in late childhood. The results suggest a sex-specific programming effect of early pregnancy vitamin D3 levels on offspring body composition into late childhood observed in boys.

25 Apr 2023

Acylceramides and protein-bound ceramides are vital for the formation of oral barrier in mice

Acylceramides and protein-bound ceramides are vital for the formation of the oral barrier in mice, similar to their role in skin, protecting from infection.

12 Apr 2023

Insulin most likely has a longer shelf life at room temperature, study shows

An international study shows that it is likely that insulin can be stored at room temperature, and for considerably longer than drug companies have counted on to date.

11 Apr 2023

Study suggests potential therapeutic targets for COVID-19-related neurological pathologies

In a recent study published in the journal Molecular & Cellular Proteomics, researchers analyzed the proteins in cerebrospinal fluid (CSF) samples obtained from African green monkeys and rhesus macaques infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 to understand the neurological manifestations of coronavirus disease 2019 (COVID-19).

9 Apr 2023

Lipid Nanoparticles (LNPs) and DNA delivery – unlocking the future of medical research

In this interview, Kate Stumpo speaks to Michael Girgis about Lipid nano particles, and the future of the field.

From Bruker Life Sciences Mass Spectrometry 31 Mar 2023

An apple a day keeps the doctor away: polyphenol-enriched apples alter immune cell gene expression and fecal microbiota composition

Researchers compared the effects of consuming red-fleshed apples and white-fleshed among healthy adults.

29 Mar 2023

Targeting obesity: findings reveal a new molecular pathway involved in energy homeostasis regulation

Study outlines molecular mechanisms to aid the development of new therapies to manage obesity and associated health disorders.

29 Mar 2023

High-resolution mass spectrometric rapid identification of Candida auris

A recent study published in the Journal of Fungi used a novel OrbitrapTM high-resolution mass spectrometric technology coupled with liquid chromatography to identify geographically different clades of Candida auris (C. auris) isolates. This proof-of-concept methodology could accurately detect C. auris in the microbiology laboratory.

23 Mar 2023

Zoonotic agent Erysipelothrix rhusiopathiae caused mass mortality of harbor porpoises

In a recent article published in the Emerging Infectious Diseases Journal, researchers in the Netherlands described a mortality event that killed hundreds of harbor porpoises (Phocoena phocoena), a small cetacean, along the Netherlands coastline, in August 2021.

22 Mar 2023

Study identifies link between oral and gut microbiomes and depression

Researchers investigate the role of the oral-gut-brain axis in anxiety and depression.

14 Mar 2023

EVOSEP and ReSyn Biosciences partner to integrate their technologies into new clinical proteomics solutions

The ability to process large and clinically relevant cohorts in a robust and high-throughput manner is important to unlocking the full potential of proteomics for precision medicine.

From Evosep 14 Mar 2023

Bispecific antibody shows improved efficacy against SARS-CoV-2 variants

Researchers from The University of Texas MD Anderson Cancer Center have developed fully human bispecific antibodies, as revealed in a recent study. These antibodies can bind to two distinct epitopes of the receptor binding domain (RBD) of the SARS-CoV-2 spike protein and have demonstrated the ability to neutralize various strains of the virus, including the Omicron variant.