Mammalian Cells News and Research

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OXGENE introduces SLIM platform for discovery of antibodies against membrane proteins

OXGENE™ announces the introduction of its self-labelling integral membrane (SLIM™) protein discovery system.

12 Jan 2021

Biomarkers can predict how genetically identical cells behave differently under stress

A set of biomarkers not traditionally associated with cell fate can accurately predict how genetically identical cells behave differently under stress, according to a UT Southwestern study.

8 Jan 2021

Single-dose nanoparticle COVID-19 vaccine elicits virus-neutralizing antibody response in mice

Across the world, health care workers and high-risk groups are beginning to receive COVID-19 vaccines, offering hope for a return to normalcy amidst the pandemic.

8 Jan 2021

New UCLA-developed device transfers mitochondria into 100,000 or more recipient cells

Scientists from the UCLA Jonsson Comprehensive Cancer Center have developed a simple, high-throughput method for transferring isolated mitochondria and their associated mitochondrial DNA into mammalian cells.

29 Dec 2020

HDL nanoparticles prevent cholesterol movement at membrane receptor to inhibit entry of SARS-CoV-2 pseudovirus in cell culture

As researchers strive to find safe therapeutics for COVID 19, a study suggests that preventing the movement of cholesterol may inhibit viral entry by up to 80%.

17 Dec 2020

Researchers design new chemical tool with high configurational stability, catalytic activity

Researchers have designed and built a new chemical tool inspired by natural metal-containing enzymes in living organisms. The product, a tetrahedral "chiral zinc", maintains its shape for years, providing a new structure with exciting possibilities for manufacturing pharmaceuticals and optical electronics.

15 Dec 2020

Researchers identify new mechanism through which plants can regulate gene expression

Just like other organisms, plants must respond dynamically to a variety of cues over their lifetime. Going through different developmental stages, or altering their form in response to a drought or drastic temperature change requires altering which of their genes are expressed into proteins and when those processes occur.

8 Dec 2020

Rice biochemist discovers hidden structure in essential metabolic machinery

In his first year of graduate school, Rice University biochemist Zachary Wright discovered something hidden inside a common piece of cellular machinery that's essential for all higher order life from yeast to humans.

5 Dec 2020

New understanding of glycan signatures of the SARS-COV-2 S1 spike protein

A team of scientists from the University of Oxford, UK, has revealed that site-specific glycosylation differs between spike proteins derived from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and a viral vector-based vaccine candidate.

18 Nov 2020

Nanobodies efficiently neutralize SARS-CoV-2 in cells

Two separate studies have identified nanobodies - which could be produced less expensively than monoclonal antibodies - that bind tightly to the SARS-CoV-2 spike protein and efficiently neutralize SARS-CoV-2 in cells.

5 Nov 2020

Cell biologists and bioimaging expert team up to solve fourth dimension secrets

Cell biologists at the University of Illinois at Urbana-Champaign and Bar-Ilan University at Israel and a bioimaging expert at the University of Central Florida are teaming up in what they hope may lead to a major breakthrough in understanding of the three-dimensional organization of the nucleus over time and their role in certain diseases.

29 Oct 2020

Scientists devise new method to map HIV's sugary shield in unprecedented detail

Scientists from Scripps Research and Los Alamos National Laboratory have devised a method for mapping in unprecedented detail the thickets of slippery sugar molecules that help shield HIV from the immune system.

23 Oct 2020

New DNA-cutting tool could advance gene editing for novel treatments

Gene editing for the development of new treatments, and for studying disease as well as normal function in humans and other organisms, may advance more quickly with a new tool for cutting larger pieces of DNA out of a cell's genome, according to a new study by UC San Francisco scientists.

21 Oct 2020

Minuscule tracking devices show how living cells change with time

For the first time, scientists have introduced minuscule tracking devices directly into the interior of mammalian cells, giving an unprecedented peek into the processes that govern the beginning of development.

20 Oct 2020

Many coronavirus strains found in animals can also infect humans, shows study

New research from the University of North Carolina at Chapel Hill suggests that a strain of coronavirus that has recently alarmed the swine industry may have the potential to spread to humans as well.

14 Oct 2020

Study shows effective light-induced inactivation of SARS-CoV-2 with conjugated oligomers and polymers

A new pilot study by US researchers demonstrates an alternative approach to long-lasting disinfection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by using cationic phenylene ethynylene polymers and oligomers (i.e., conjugated electrolytes). The paper is currently available on medRxiv* preprint server.

7 Oct 2020

Endocannabinoids in the body can help fight intestinal infections

Endocannabinoids, signaling molecules produced in the body that share features with chemicals found in marijuana, can shut down genes needed for some pathogenic intestinal bacteria to colonize, multiply, and cause disease, new research led by UT Southwestern scientists shows.