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New study confirms brain's waste-clearance pathways in humans

Scientists have long theorized about a network of pathways in the brain that are believed to clear metabolic proteins that would otherwise build up and potentially lead to Alzheimer's and other forms of dementia. But they had never definitively revealed this network in people -; until now.

7 Oct 2024

New cell therapy offers effective treatment for patients with T-cell acute lymphoblastic leukemia

A new cell therapy, targeting CD7 on leukaemia cells, gives a potentially effective treatment for patients with T-cell acute lymphoblastic leukaemia (T-ALL) who have exhausted all standard treatment options.

7 Oct 2024

Researchers reveal mechanisms of how CDK12 alterations drive prostate cancer development

When researchers at the University of Michigan Rogel Cancer Center first identified a new subtype of aggressive prostate cancer, they knew they needed to understand how this genetic alteration was driving cancer and how to target it with treatment.

4 Oct 2024

Jefferson Lab team explores proton therapy as a safer cancer treatment

Radiation therapy techniques have been used for more than a century to treat cancers. Physicists in the Radiation Detector and Imaging group and associated with the Biomedical Research & Innovation Center (BRIC) at the U.S. Department of Energy's Thomas Jefferson National Accelerator Facility have been for several years pursuing radiation therapy technology improvements in collaboration with the Hampton University Proton Cancer Institute (HUPCI).

4 Oct 2024

New X-ray technique reveals metal ion role in antibiotic efficacy

Researchers from City St George's, University of London have used a new ultra-high precision x-ray scattering technique to unveil the location and identity of metal ions in bacteria that are crucial for antibiotics to work optimally.

4 Oct 2024

Stem cell transplants show promise for macular hole repair in monkeys

Human stem cell transplants successfully repaired macular holes in a monkey model, researchers report October 3rd in the journal Stem Cell Reports. After transplantation, the macular holes were closed by continuous filling of the space with retinal tissue.

3 Oct 2024

Fruit fly brain connectome offers critical clues for understanding brain function and behavior

A scientific team supported by the National Institutes of Health (NIH) unveiled the first complete map of the neural connections of the common fruit fly brain. The map provides a wiring diagram, known as a connectome, and is the largest and most complete connectome of an adult animal ever created.

3 Oct 2024

Accelerating tobacco decline could boost global life expectancy

Accelerating the decline in tobacco smoking globally, by decreasing smoking prevalence from current levels to 5% everywhere, could increase life expectancy and prevent millions of premature deaths by 2050, according to a study from the Global Burden of Disease, Injuries and Risk Factors (GBD) Tobacco Forecasting Collaborators published in The Lancet Public Health journal.

3 Oct 2024

UK and Singapore partner on health data

Health Data Research UK (HDR UK) and the National Research Foundation Singapore (NRF) are pleased to have signed a Memorandum of Understanding (MoU) today, that formalizes a collaborative partnership in healthcare and data science.

3 Oct 2024

Creating a tobacco-free generation could prevent 1.2 million lung cancer deaths

Creating a generation of people who never smoke could prevent 1.2 million deaths from lung cancer globally, according to a study led by researchers from the University of Santiago de Compostela, the International Agency for Research on Cancer (IARC), and global collaborators published in The Lancet Public Health journal.

3 Oct 2024

Online insomnia treatment brings relief to overburdened caregivers

Providing care for a family member with a disabling illness can be a demanding job that leaves many people unable to sleep, but an online insomnia treatment developed at the University of Virginia School of Medicine can help, new research shows.

2 Oct 2024

Research heralds in a new era for genetic sequencing and testing

Research led by scientists at Queen Mary University of London is heralding in a new era for genetic sequencing and testing.

1 Oct 2024

Umbilical cord blood transplants improve cancer survival rates across all races

Patients who receive umbilical cord blood transplants for blood cancers now live equally long regardless of their race, new research from UVA Cancer Center shows.

1 Oct 2024

Survey reveals strong public backing for ending animal testing in scientific research

A new survey shows that Americans' attitudes toward experiments on animals have changed significantly in recent years, with the vast majority now favoring phasing out animal experiments in favor or other research methods.

30 Sep 2024

AI-powered blood test promises early detection of ovarian cancer

A blood test that uses artificial intelligence (AI) to detect cancer-related genetic changes and protein biomarkers could help screen women for early signs of ovarian cancer, according to a study by researchers at the Johns Hopkins Kimmel Cancer Center in collaboration with several other institutions in the United States and Europe.

30 Sep 2024

Epigenetic switch controls renin production in unexpected cell type

University of Virginia School of Medicine researchers have discovered how certain cells have the amazing ability to transform their function to help our bodies control our blood pressure.

26 Sep 2024

Scientists unravel the process of pore formation in cells

The formation of pores by a particular protein, gasdermin D, plays a key role in inflammatory reactions. During its activation, an inhibitory part is split off. More than 30 of the remaining protein fragments then combine to form large pores in the cell membrane, which allow the release of inflammatory messengers.

26 Sep 2024