Medicinal Chemistry News and Research

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Novel molecular structures developed for desired transcriptional response

Insilico Medicine announces the publication of a new research paper titled "Molecular Generation for Desired Transcriptome Changes With Adversarial Autoencoders" in Frontiers in Pharmacology

20 May 2020

Researchers develop potential drug compound for treating cancer

Researchers at the University of Eastern Finland have developed a new and promising drug compound for the treatment of cancer that inhibits natural amino acids from entering cancer cells.

18 May 2020

Research reveals mechanism underlying Parkinson's dyskinesia

Many people with Parkinson's disease eventually develop debilitating movements called dyskinesia, a side effect of their much-needed dopamine replacement medication.

3 May 2020

Scientists generate molecular models of compounds relevant for COVID-19

The discovery of suitable drugs that could help treat diseases is a long process. However, computer-aided drug design and simulation could speed up the process and also increase the possibilities say experts. This form of drug design and simulation could soon be the gold standard in drug development.

30 Apr 2020

New Elsevier Coronavirus Research Hub offers free access to biomedical research tools, content

Elsevier, a global leader in information analytics specializing in science and health, is offering free access to a unique set of biomedical research tools and content to help researchers and life science companies accelerate efforts to address the current pandemic.

30 Apr 2020

Innovative STM method may lead to new, purer pharmaceuticals

A research project led by chemists at the University of Warwick first used ultrahigh resolution scanning tunnelling microscopy to see the exact location of atoms and bonds within a molecule, and then employed these incredibly precise images to determine the interactions that bond molecules to one another.

30 Apr 2020

UAB to join international effort to test drugs for COVID-19

The University of Alabama at Birmingham will join an international effort coordinated by Scripps Research to test drugs for COVID-19.

24 Apr 2020

COST Action creates “Task Force” of researchers to contribute to Covid-19 research

STRATAGEM COST Action (New diagnostic and therapeutic tools against multidrug resistant tumors) has created a "Task Force" of researchers contributing to Covid-19 research.

23 Apr 2020

Scripps Research established international network to find antiviral compounds against COVID-19

With the COVID-19 pandemic continuing to spread around the globe, Scripps Research has quickly established an international network of collaborating scientific laboratories to leverage ReFRAME, the world's leading drug repurposing collection, to find antiviral compounds against the novel coronavirus.

22 Apr 2020

Scripps Research establishes collaborative global effort to rapidly find drugs against COVID-19

With the COVID-19 pandemic continuing to spread across the globe, Scripps Research has quickly established an international network of collaborating scientific laboratories to leverage ReFRAME, the world's leading drug repurposing collection, to find antiviral compounds against the novel coronavirus.

16 Apr 2020

Texas A&M chemists focus on searching for drugs to treat COVID-19

In the wake of the novel coronavirus pandemic, Texas A&M University chemist Wenshe Ray Liu and his research team have focused their lab solely on searching for drugs to treat COVID-19.

6 Apr 2020

Giant Madeiran squill likely to have accumulated antibiotics from contaminated soil

A previous study has shown that a type of squill growing in Madeira produces a chemical compound that may be useful as a medicinal drug.

5 Apr 2020

New family of molecules to join altered receptors in Alzheimer's, Parkinson's and Huntington's

An article published in the Journal of Medicinal Chemistry shows a new family of molecules with high affinity to join imidazoline receptors, which are altered in the brain of those patients with neurodegenerative diseases such as Alzheimer's, Parkinson's and Huntington's.

3 Apr 2020

Fast & reliable tracking of Coronavirus patient samples

Ziath Ltd. has received orders for its DataPaq™ Mirage Rack Scanner from a growing number of laboratories that specialise in testing patient samples for Coronavirus Covid-19 infection.

From Ziath Ltd 27 Mar 2020

New molecular probes to study the behavior of opioid receptors

It could be an important step forward in the improvement of pain therapy: Thanks to newly developed molecular probes, the behavior of individual opioid receptors can now be studied in detail.

25 Mar 2020

Baylor College of Medicine and UH team up for new research collaborations

Baylor College of Medicine and the University of Houston are teaming up for new research collaborations.

10 Mar 2020

Novel compounds show promise as potent new treatment for malaria

A novel class of antimalarial compounds that can effectively kill malaria parasites has been developed by Australian and US researchers.

4 Mar 2020

Research could provide more effective way to treat brain swelling after stroke

Cases of potentially deadly brain damage as a result of stroke could be reduced after new research identified a pathway in the brain that causes swelling, and which responds to an innovative treatment.

2 Mar 2020

New compounds may help stop the spread of the coronavirus

Amid the global health crisis of the coronavirus (COVID-19), scientists from around the world are racing to find a treatment to stop the deadly virus. The sudden acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread across 46 countries, infecting more than 82,000 and killing more than 2,800 people.

26 Feb 2020

Re-engineered plant compound reduces morphine-seeking behaviors in mice

The abuse of prescription and illegal opioids, such as morphine and heroin, is a major problem in the U.S., with devastating public health, economic and social consequences.

5 Feb 2020