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Lactate instead of glucose after traumatic brain injury

The chemical lactate has gotten a bad rap. Conventional wisdom considered it to be little more than the bane of runners and other athletes, causing stiff muscles and fatigue, and the "sour" in sour milk. It turns out that view may have been too narrow.

15 Apr 2007

Ranbaxy receives U.S. approval to market Loratadine Antihistamine tablets

Ohm Laboratories, a wholly owned subsidiary of Ranbaxy Laboratories Limited, has announced that Ranbaxy has received approval from the U. S. Food and Drug Administration to manufacture and commercialize its Loratadine Orally Disintegrating Tablets, 10mg. The antihistamine previously made the switch from the prescription to the OTC market.

15 Apr 2007

Laser technique to identify deadly anthrax

Texas A&M University and Princeton University physicists have joined forces to perfect a powerful new weapon in the war on terrorism – a laser technique to identify deadly anthrax spores.

15 Apr 2007

Link between immune system and high plasma lipid levels

Researchers at the University of Chicago have found an unsuspected link between the immune system and high plasma lipid levels (cholesterol and triglycerides in the blood) in mice.

15 Apr 2007

Cytokinetics initiates of phase II clinical trial for CK-1827452

Cytokinetics has announced the initiation of a Phase II clinical trials program evaluating CK-1827452, a novel cardiac myosin activator for the potential treatment of patients with either acutely decompensated or chronic heart failure.

15 Apr 2007

Bacteria can barge inside immune cells

Immune cells that are the body's front-line defense don't necessarily rest quietly until invading bacteria lock onto receptors on their outside skins and rouse them to action, as previously thought. In a new paper, University of Michigan scientists describe their findings that bacteria can barge inside these guard cells and independently initiate a powerful immune response.

14 Apr 2007

Three proteins could be new targets for treating stroke, brain and spinal cord injuries

Some mature brain cells can grow new extensions when the amount of three particular proteins on their surface increases, a new study shows.

12 Apr 2007

Breakthrough in photoswitchable fluorescent protein science

University of Oregon scientists have identified molecular features that determine the light-emitting ability green fluorescent proteins, and by strategically inserting a single oxygen atom they were able to keep the lights turned off for up to 65 hours.

11 Apr 2007

Pharmacopeia announces positive results in hypertension and diabetic nephropathy trial

Pharmacopeia ( NASDAQ:PCOP ) , an innovator in the discovery and development of novel small molecule therapeutics, today announced positive results from the initial Phase 1 clinical trial of PS433540, the company's lead internal product candidate for the treatment of hypertension and diabetic nephropathy.

11 Apr 2007

Renovis and Pfizer extend research collaboration

Renovis has announced an agreement with Pfizer to extend the term of the companies' worldwide collaboration to research, develop and commercialize small molecules that target the vanilloid receptor, VR1.

11 Apr 2007

FASgen awarded grant for refinement of its serum fatty acid synthase

FASgen has announced that it has been awarded an SBIR grant from National Cancer Institute for refinement of its serum FAS (fatty acid synthase) ELISA cancer diagnostic test, FAS- Detect ELISA.

10 Apr 2007

Scientists link treatment-induced growth factor to cancer spread

In advanced cancer, anti-tumor therapies often work only partially or not at all, and tumors progress following treatment.

7 Apr 2007

New regulatory mechanism for critical protein signaling domain

The study is being published in Science Express, an advanced online edition of the journal Science, on April 5. It will appear in the print version of Science later this spring.

7 Apr 2007

Scientists decode genome of Streptococcus sanguinis

Virginia Commonwealth University researchers have decoded the genome of a bacteria normally present in the healthy human mouth that can cause a deadly heart infection if it enters the bloodstream.

7 Apr 2007

Potential target for the development of a drug to treat memory loss

A mind-altering mutation in mice results in an enhanced long-term memory, researchers report in the April 6, 2007 issue of the journal Cell, published by Cell Press.

7 Apr 2007

Alteon expands agreement with Biorap Technologies

Alteon has announced that it has entered into an expanded licensing agreement with BioRap Technologies, the commercialization arm of the Rappaport Family Institute for Research, Technion University, Israel, for all diagnostic devices or products for predictive purposes in vascular or cardiac diseases, including diagnostic assays for the measurement of the haptoglobin protein (Hp).

7 Apr 2007

Method for making new molecules based on flavonoids - implications for cancer therapeutics

You've heard of them -- the good-for-your-health compounds found in plants that we enjoy in red wine, dark chocolate, green tea and citrus fruits.

5 Apr 2007

UT Metroplex institutions to collaborate on biomedical research

Researchers from the three University of Texas campuses in the Dallas-Fort Worth metropolitan area are combining their expertise in biomedical science, engineering and physical sciences on projects aimed at solving real-world medical problems.

5 Apr 2007

Researchers identify 221 genes possibly related to addiction vulnerability

Scientists supported by the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health, have for the first time identified genes that might increase a person's ability to abstain from smoking.

4 Apr 2007

New findings on hypoglycemic neuronal death

Treatment with insulin revolutionized the life of individuals with diabetes. However, because insulin acts to lower blood glucose levels, it can cause hypoglycemia (low levels of glucose in the blood), which, if prolonged, can lead to brain injury and coma.

4 Apr 2007