Nephropathy News and Research

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Nephropathy is a broad medical term used to denote disease or damage of the kidney, which can eventually result in kidney failure. The primary and most obvious functions of the kidney are to excrete any waste products and to regulate the water and acid-base balance of the body – therefore loss of kidney function is a potentially fatal condition.

Transgenic fruit flies can shed light on genetic mutations that underlie kidney disease in humans

An off-the-shelf dietary supplement available for pennies per dose demonstrated the ability to reverse cellular damage linked to specific genetic mutations in transgenic fruit flies, an experimental model of genetic mutation-induced renal cell injury that features striking similarities to humans, a Children's National Health System research team reports April 20 in Journal of the American Society of Nephrology.

21 Apr 2017

Scientists identify genetic clues to chronic kidney disease

Using international genomic studies backed by proof-of-concept cell experiments, researchers have identified two genes that contribute to the chronic kidney disease glomerulonephritis.

16 Mar 2017

New research reveals link between sickle cell trait and increased risk of developing kidney failure

New research indicates that being born with one copy of the sickle gene puts an individual at elevated risk for developing kidney failure requiring dialysis.

10 Mar 2017

High levels of folate during pregnancy may decrease hypertension risk in children

A new article published in the American Journal of Hypertension finds that babies born to mothers with cardiometabolic risk factors were less likely to develop high blood pressure if their mothers had higher levels of folate during pregnancy.

8 Mar 2017

New drug-like compound shows potential to treat symptoms of lupus

Lupus, a chronic autoimmune disease, has proved difficult to treat, but a new international study co-led by a Rush University Medical Center researcher suggests that a drug starting through the pipeline could ameliorate or even eliminate the symptoms in most sufferers.

7 Mar 2017

Researchers uncover new genetic clues linked to autoimmune kidney disease

Researchers have uncovered new genetic clues to understanding IgA nephropathy (IgAN), or Berger's disease, an autoimmune kidney disease and a common cause of kidney failure.

6 Mar 2017

International consortium aims to improve therapeutic options for diabetes-induced kidney disease

Chronic kidney disease is a frequently encountered disorder: more than 10% of the population suffer from such problems.

3 Mar 2017

FDA approves new nasal spray for adults who overproduce urine at night

The U.S. Food and Drug Administration today approved Noctiva (desmopressin acetate) nasal spray for adults who awaken at least two times per night to urinate due to a condition known as nocturnal polyuria (overproduction of urine during the night).

3 Mar 2017

Case Western Reserve and VA team up to tackle rising problem of antibiotic resistance

Since the discovery of penicillin in 1928, antibiotics have made the world a much safer and healthier place. But Shakespeare was onto something when he asked if it's possible to have too much of a good thing. In the case of antibiotics, the answer is increasingly "yes."

3 Mar 2017

Study finds mobile health clinics as powerful tool to engage patients in care

Patients treated at mobile health clinics report a high level of engagement in their care and the motivation to pursue healthy behaviors, according to the results of a qualitative study led by Zoe Bouchelle, Harvard Medical School Class of 2017, and communications scholar Heather Carmack of James Madison University.

2 Mar 2017

Highly prevalent gene variants in African Americans contribute to kidney disease

African Americans have a heightened risk of developing chronic and end-stage kidney disease. This association has been attributed to two common genetic variants - named G1 and G2 -- in APOL1, a gene that codes for a human-specific protein.

1 Mar 2017

Study reveals high burden of health complications in adolescents, young adults with type 2 diabetes

A new report published in the Feb. 28 issue of the Journal of the American Medical Association points to a significantly higher burden of diabetes-related complications in adolescents and young adults with type 2 diabetes compared to type 1 diabetes, with greater health complications in minority youth.

28 Feb 2017

Young children experience better long-term kidney transplant success than adults, study finds

The success of kidney transplants has vastly improved for children over the past half-century, with young children now experiencing better long-term transplant success than adults, according to study results from a large pediatric transplant center.

27 Feb 2017

HIV-infected individuals with kidney failure less likely to receive necessary transplant, study finds

A new study finds that HIV-infected individuals with kidney failure are less likely to receive a kidney transplant—especially from living donors—than their uninfected counterparts.

24 Feb 2017

Initial diagnosis of acute kidney injury may be inaccurate for many patients, study suggests

Researchers from Columbia University Medical Center have found that, for many patients, an initial diagnosis of "acute kidney injury" may have been inaccurate.

24 Feb 2017

Researchers reveal biological pathways involved in diabetic kidney disease

Diabetes is a leading cause of kidney disease, a serious, often fatal complication that is difficult to diagnose in early, potentially treatable stages.

24 Feb 2017

Research shines new light on role of AKI in development of lung injury

Acute kidney injury (AKI) is sudden kidney failure or damage lasting from a few hours to several days. During this time, the kidney's ability to maintain a proper balance of bodily fluids is compromised and causes a buildup of waste products in the blood.

22 Feb 2017

Prolonged use of popular heartburn drugs linked to silent, gradual kidney damage

Taking popular heartburn drugs for prolonged periods has been linked to serious kidney problems, including kidney failure.

22 Feb 2017

Scientists explore role of salt and immune system in raising blood pressure of females

Many of us have noted how our hands and feet swell after eating too much salt. Now scientists are exploring how high salt intake can also make cells throughout the body of females swell, rupture, dump their contents and die, triggering an immune reaction that contributes to chronic high blood pressure.

22 Feb 2017

High dietary potassium and low sodium can help improve risk factors for heart, kidney disease

Reducing sodium in the diet has been recommended to lower blood pressure and the risk of heart disease.

21 Feb 2017

Nephropathy News and Research

Further Reading

Transgenic fruit flies can shed light on genetic mutations that underlie kidney disease in humans

Scientists identify genetic clues to chronic kidney disease

New research reveals link between sickle cell trait and increased risk of developing kidney failure

High levels of folate during pregnancy may decrease hypertension risk in children

New drug-like compound shows potential to treat symptoms of lupus

Researchers uncover new genetic clues linked to autoimmune kidney disease

International consortium aims to improve therapeutic options for diabetes-induced kidney disease

FDA approves new nasal spray for adults who overproduce urine at night

Case Western Reserve and VA team up to tackle rising problem of antibiotic resistance

Study finds mobile health clinics as powerful tool to engage patients in care

Highly prevalent gene variants in African Americans contribute to kidney disease

Study reveals high burden of health complications in adolescents, young adults with type 2 diabetes

Young children experience better long-term kidney transplant success than adults, study finds

HIV-infected individuals with kidney failure less likely to receive necessary transplant, study finds

Initial diagnosis of acute kidney injury may be inaccurate for many patients, study suggests

Researchers reveal biological pathways involved in diabetic kidney disease

Research shines new light on role of AKI in development of lung injury

Prolonged use of popular heartburn drugs linked to silent, gradual kidney damage

Scientists explore role of salt and immune system in raising blood pressure of females

High dietary potassium and low sodium can help improve risk factors for heart, kidney disease

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