Neurodegeneration News and Research

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Neurodegeneration is the umbrella term for the progressive loss of structure or function of neurons, including death of neurons.

Loss of Golgi function may contribute to pathology of neurodegenerative diseases

Disabling a part of brain cells that acts as a tap to regulate the flow of proteins has been shown to cause neurodegeneration, a new study from The University of Manchester has found.

From The University of Manchester 9 Feb 2017

Scientists discover treatment that improves symptoms in mouse model of juvenile Batten disease

Researchers at Baylor College of Medicine, Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital and King's College London have discovered a treatment that improves the neurological symptoms in a mouse model of juvenile Batten disease.

6 Feb 2017

Study provides insights into functions of astrocytes following brain injury or disease

Astrocytes have long been implicated in the pathology of a range of human neurodegenerative diseases or injuries including Alzheimer's, Huntington's Parkinson's disease, brain trauma and spinal cord injury.

3 Feb 2017

Study reveals new molecular mechanism vital for associative memory encoding in the hippocampus

A new study, published on the cover of the scientific journal Biological Psychiatry and lead by Dr Carlos Saura from the Institut de Neurociències at the Universitat Autònoma de Barcelona, reveals a new molecular mechanism essential for associative memory encoding in the hippocampus.

31 Jan 2017

Edible and medicinal mushrooms show potential to mitigate neurodegenerative diseases

Certain edible and medicinal mushrooms contain bioactive compounds that may enhance nerve growth in the brain and protect against neurotoxic stimuli such as inflammation that contribute to neurodegenerative diseases like dementia and Alzheimer's disease.

24 Jan 2017

Researchers find new way to quantify olfactory sensory neurons using PET radiotracer

Olfactory health - how well we are able to smell - is a reliable marker of the health of the brain, but the "smell identification tests" commonly used in studies of olfactory health do not offer a complete picture of what is happening.

24 Jan 2017

Exeter scientists discover how two cell organelles interact at molecular level

Scientists have made a breakthrough in understanding how different compartments (or organelles) of human cells interact.

20 Jan 2017

Selonterra publishes article on novel APOE4 mechanism linked to Alzheimer’s disease

Selonterra LLC, a biotechnology company discovering therapies for Alzheimer’s disease and Parkinson’s disease announced the publication of the article “Identification of a Nuclear Respiratory Factor 1 Recognition Motif in the Apolipoprotein E Variant APOE4 linked to Alzheimer’s Disease” in Scientific Reports, a peer-reviewed journal of the Nature Publishing Group.

19 Jan 2017

Concussions accelerate Alzheimer's disease-related brain atrophy and cognitive decline, research finds

New research has found concussions accelerate Alzheimer's disease-related brain atrophy and cognitive decline in people who are at genetic risk for the condition.

12 Jan 2017

Could pathogen infection really lead to Alzheimer’s?

New concepts of infectious disease are evolving with the realization that pathogens are key players in the development of progressive chronic diseases that originally were not thought to be infectious. Infection is well-known to be associated with numerous neurological diseases for which...

12 Jan 2017

Protein aggregation may trigger inflammatory response linked to neurodegenerative diseases

A recent review article published online in The FASEB Journal points to the "trigger" for the inflammatory response, caused by the immune system, that precedes Alzheimer's disease and other neurological conditions.

11 Jan 2017

Molecular pharmacologist granted funding to unravel mechanisms of neuronal communication

Our ability to memorize our first kiss or the last day at school as most other functions of the brain relies on communication between nerve cells at special contacts called synapses, where chemical signals are conveyed from one nerve cells to the next.

6 Jan 2017

How does the brain control appetite?

Energy balance between energy intake and expenditure in our bodies is important for maintaining energy homeostasis to keep our bodies functioning properly. The appetite determines how much we eat, the energy intake, by communication between the brain and body.

4 Jan 2017

Scientists discover OGDHL and NRD1 genes linked to progressive loss of neurological function

An international team of scientists has discovered that the gene, OGDHL, a key protein required for normal function of the mitochondria -- the energy-producing factory of the cell -- and its chaperone, nardilysin (NRD1) are linked to progressive loss of neurological function in humans.

22 Dec 2016

Popular food supplement may be key in reversing detrimental effects of Familial Dysautonomia

A new Tel Aviv University study finds that a popular food supplement called phosphatidylserine may be instrumental in reversing the detrimental effects of Familial Dysautonomia (FD), a debilitating neurodegenerative disorder that affects approximately 1 in 31 Jewish people of Eastern European, or Ashkenazi, ancestry.

21 Dec 2016

Scientists identify potential drug treatment in fight against Alzheimer’s disease

An international team of scientists has announced a new advance in the fight against Alzheimer’s disease by identifying a new drug target for not only improving symptoms of brain degeneration – but also to extend the life-span of the terminally ill mice.

21 Dec 2016

Scientists detail structure of molecule implicated in Alzheimer's disease

Scientists at Washington University School of Medicine in St. Louis have detailed the structure of a molecule that has been implicated in Alzheimer's disease.

21 Dec 2016

Landmark clinical trial to test third investigational drug for Alzheimer's disease

An international team led by Washington University School of Medicine in St. Louis has selected a third investigational drug to be tested in a worldwide clinical trial - already underway - aimed at finding treatments to prevent Alzheimer's disease.

20 Dec 2016

Research into common congenital brain defect identifies molecular basis

Scientists at Sanford Burnham Prebys Medical Discovery Institute (SBP) have discovered a molecular cause of hydrocephalus, a common, potentially life-threatening birth defect in which the head is enlarged due to excess fluid surrounding the brain.

14 Dec 2016

Upright posture in patients with Parkinson's disease exacerbates cognitive deficits, study shows

In a new study published online today in the journal Neurology, a research team led by neurologists at Beth Israel Deaconess Medical Center and neuropsychologists at Boston University has shown that when patients with Parkinson's disease experience a drop in blood pressure upon standing up - a condition known as orthostatic hypotension (OH) - they exhibit significant cognitive deficits.

30 Nov 2016

Neurodegeneration News and Research

Further Reading

Loss of Golgi function may contribute to pathology of neurodegenerative diseases

Scientists discover treatment that improves symptoms in mouse model of juvenile Batten disease

Study provides insights into functions of astrocytes following brain injury or disease

Study reveals new molecular mechanism vital for associative memory encoding in the hippocampus

Edible and medicinal mushrooms show potential to mitigate neurodegenerative diseases

Researchers find new way to quantify olfactory sensory neurons using PET radiotracer

Exeter scientists discover how two cell organelles interact at molecular level

Selonterra publishes article on novel APOE4 mechanism linked to Alzheimer’s disease

Concussions accelerate Alzheimer's disease-related brain atrophy and cognitive decline, research finds

Could pathogen infection really lead to Alzheimer’s?

Protein aggregation may trigger inflammatory response linked to neurodegenerative diseases

Molecular pharmacologist granted funding to unravel mechanisms of neuronal communication

How does the brain control appetite?

Scientists discover OGDHL and NRD1 genes linked to progressive loss of neurological function

Popular food supplement may be key in reversing detrimental effects of Familial Dysautonomia

Scientists identify potential drug treatment in fight against Alzheimer’s disease

Scientists detail structure of molecule implicated in Alzheimer's disease

Landmark clinical trial to test third investigational drug for Alzheimer's disease

Research into common congenital brain defect identifies molecular basis

Upright posture in patients with Parkinson's disease exacerbates cognitive deficits, study shows

Aneuro: A Year of Neuroscience in Review eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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