Neurogenesis News and Research

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Neurogenesis (birth of neurons) is the process by which neurons are generated. Most active during pre-natal development, neurogenesis is responsible for populating the growing brain.

Study reveals sex-differences in aging of the brain stem cell niche

Ageing and age-related brain disease do not affect women and men in the same way. The adult brain constantly generates new brain cells called neurons from stem cells, a process called neurogenesis.

7 Apr 2021

Researchers discover a novel marker of adult human neural stem cells

The mammalian center for learning and memory, hippocampus, has a remarkable capacity to generate new neurons throughout life. Newborn neurons are produced by neural stem cells (NSCs) and they are crucial for forming neural circuits required for learning and memory, and mood control.

24 Mar 2021

Researchers reprogram glial cells into new neurons to heal spinal cord injury

Researchers at Indiana University School of Medicine have successfully reprogrammed a glial cell type in the central nervous system into new neurons to promote recovery after spinal cord injury--revealing an untapped potential to leverage the cell for regenerative medicine.

8 Mar 2021

Researchers discover a mechanism linked to stem cell aging

As people get older, their neural stem cells lose the ability to proliferate and produce new neurons, leading to a decline in memory function.

24 Feb 2021

Brain pericytes serve as a potential hub for SARS-CoV-2 infection

A team of scientists from the United States has recently conducted a study using pericyte-like cell-containing brain cortical organoids as an experimental model to investigate the impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on the central nervous system.

11 Feb 2021

New research examines how alcohol exposure impacts aspects of neuroplasticity

New research and analysis examine how alcohol exposure impacts many aspects of neuroplasticity in a special issue of Brain Plasticity

11 Feb 2021

Traumatic or stressful events in childhood may lead to changes in key brain structures

A new study from University of Alberta researchers has shown that traumatic or stressful events in childhood may lead to tiny changes in key brain structures that can now be identified decades later.

9 Feb 2021

Study implicates disruption in prenatal neurogenesis in the development of ASDs

A new study of autism risk genes by UC San Francisco and UC Berkeley scientists implicates disruption in prenatal neurogenesis - a process in which specialized "progenitor" cells give rise to new brain cells - in the development of autism spectrum disorders (ASDs).

8 Feb 2021

How does SARS-CoV-2 infect brain cells?

Researchers from the University of California San Francisco, Gladstone Institutes in the USA, and The Aga Khan University in Pakistan investigated if human neural cells can be infected by SARS-CoV-2.

20 Jan 2021

Reductive stress promotes protein aggregation in neuroblastoma cells, impairs neurogenesis

Cells require a balance among oxidation-reduction reactions, or redox homeostasis. Loss of that balance to create oxidative stress is often associated with neurodegeneration. Less is known about how loss of that balance at the other end of the spectrum -- reductive stress, or RS -- may affect neurons.

8 Dec 2020

Free radicals may be important for the brain to remain adaptable

Reactive oxygen molecules, also known as "free radicals", are generally considered harmful. However as it now turns out, they control cellular processes, which are important for the brain's ability to adapt - at least in mice.

5 Dec 2020

Researchers identify specific circular RNA that regulates neurogenesis

In a screening for a functional impact to the neuronal differentiation process, Danish researchers identified a specific circular RNA, circZNF827, which surprisingly "taps the brake" on neurogenesis.

16 Nov 2020

Targeting TAAR5 can provide a new treatment opportunity for neurodegenerative disorders

St Petersburg University researchers, led by Professor Raul R. Gainetdinov, Director of the Institute of Translational Biomedicine and Academic Supervisor of the St Petersburg University Hospital, have found a new role for recently discovered neurotransmitter system that uses the trace amine-associated receptor 5 (TAAR5) for neurotransmission.

11 Nov 2020

Natural component of ayahuasca tea promotes neurogenesis

One of the main natural components of ayahuasca tea is dimethyltryptamine (DMT), which promotes neurogenesis --the formation of new neurons-- according to research led by the Complutense University of Madrid (UCM).

6 Nov 2020

Gut hormone found to be key regulator of new nerve cells in the adult brain

A gut hormone, ghrelin, is a key regulator of new nerve cells in the adult brain, a Swansea-led research team has discovered. It could help pave the way for new drugs to treat dementia in patients with Parkinson's Disease.

21 Oct 2020

Why do we need sleep?

In this interview, Dr. Gina Poe speaks to News-Medical about why we sleep, and the importance of REM sleep for brain development.

7 Oct 2020

Life-long olfactory sensory neurogenesis may have a key adaptive function

Olfactory sensory neurons are nasal neurons that make use of hundreds of different types of odorant receptors to analyze odorous chemicals in our external world and send that information to our brain.

7 Oct 2020

Study: Early training of cell development and network improves response

When it comes to training neural circuits for tissue engineering or biomedical applications, a new study suggests a key parameter: Train them young.

7 Aug 2020

Research unlocks key mechanism in the communication between brain cells during stroke

Research led by Nicolas Bazan, MD, PhD, Boyd Professor and Director of the Neuroscience Center of Excellence at LSU Health New Orleans School of Medicine, and Ludmila Belayev, MD, LSU Health New Orleans Professor of Neuroscience, Neurology and Neurosurgery, has unlocked a key fundamental mechanism in the communication between brain cells when confronted with stroke.

6 Aug 2020

New model helps study human hippocampal neurons

Neuroscientists and stem cell researchers at Lund University in Sweden have developed a research model that allows studying human hippocampal neurons, the brain cells primarily affected by Alzheimer's disease pathology.

29 Jun 2020