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Can poor diet and lifestyle behaviors modify genomic susceptibility to impulsivity?

Researchers evaluated the effects of poor diet quality and lifestyle behaviors on modifying the genomic susceptibility to impulsivity.

30 Mar 2023

Which functional and structural changes in the brain are associated with blood pressure elevation and cognitive impairment in humans?

Researchers identified brain structures related to cognitive impairment associated with elevated blood pressure (BP).

30 Mar 2023

Study finds minimal impact of SARS-CoV-2 genome variability on current diagnostic molecular systems

The authors of a new study under review at the journal Scientific Reports and currently posted to the Research Square preprint* server proposed a novel analysis pipeline to help identify mutations in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reverse transcription-polymerase chain reaction (RT-PCR) primer regions.

29 Mar 2023

COVID-19 activates endogenous retroviruses within our genome

Researchers assess the impact of SARS-CoV-2 infection on endogenous retroviruses of the LTR69 subfamily.

28 Mar 2023

JPL study uses metagenomic sequencing to monitor microbial burden on spacecraft

A recent study published in PLOS ONE uses metagenomics to examine the microbial composition in samples obtained from the Jet Propulsion Laboratory.

28 Mar 2023

Possible pathways of C. auris emergence and the hypothetical role of interspecies transmission

Researchers summarized the current understanding of the emergence and ecologic niches of Candida auris.

27 Mar 2023

High-resolution mass spectrometric rapid identification of Candida auris

A recent study published in the Journal of Fungi used a novel OrbitrapTM high-resolution mass spectrometric technology coupled with liquid chromatography to identify geographically different clades of Candida auris (C. auris) isolates. This proof-of-concept methodology could accurately detect C. auris in the microbiology laboratory.

23 Mar 2023

Candida auris infection without epidemiologic links to a prior outbreak

The Centers for Disease Control and Prevention (CDC) has classified Candida auris (C. auris) as an urgent public threat due to its role in elevating mortality, its ability to persist in hospital environments, and the high possibility of developing pan-drug resistance.

23 Mar 2023

Understanding the structure of CFTR could help design more effective therapies for cystic fibrosis

Scientists at St. Jude Children's Research Hospital and Rockefeller University have combined their expertise to gain a better understanding of the cystic fibrosis transmembrane conductance regulator (CFTR).

23 Mar 2023

Pet dogs across the USA are becoming increasingly resistant to benzimidazole treatment

In a recent study published in the journal PLOS Pathogens, researchers in the United States of America (USA) and Canada found molecular evidence that the parasitic hookworms (Ancylostoma caninum) in pet dogs across the USA are becoming increasingly resistant to benzimidazole, a broad-spectrum anthelmintic drug used for infection control.

22 Mar 2023

Zoonotic agent Erysipelothrix rhusiopathiae caused mass mortality of harbor porpoises

In a recent article published in the Emerging Infectious Diseases Journal, researchers in the Netherlands described a mortality event that killed hundreds of harbor porpoises (Phocoena phocoena), a small cetacean, along the Netherlands coastline, in August 2021.

22 Mar 2023

Higher plasma caffeine concentrations might reduce body fat and type 2 diabetes risk

In a recent study published in the journal BMJ Medicine, researchers in the United Kingdom and Sweden investigated the probable causality of long-term serum caffeine concentrations on type 2 diabetes (T2D), adiposity, and major cardiovascular diseases (CVDs).

22 Mar 2023

Study finds shared genetic risk variants across different substance use disorders

By combing through genomic data of over 1 million people, scientists have identified genes commonly inherited across addiction disorders, regardless of the substance being used.

22 Mar 2023

Childhood and adolescent obesity: time to act

In a recent review published in the journal Frontiers in Pediatrics, researchers at the Medical College of Wisconsin presented an overview of the pathophysiological mechanisms, health implications, and management options for obesity among children and adults.

21 Mar 2023

Research reports spillover of highly pathogenic avian influenza A(H5N1) into marine mammals in the northeastern United States

A recent study published in the United States (U.S.) Centers for Disease Control and Prevention (CDC) journal Emerging Infectious Diseases reported the outbreak of the highly pathogenic hemagglutinin type 5 and neuraminidase type 1 (H5N1) avian influenza virus among New England gray and harbor seals in the United States (U.S.)

20 Mar 2023

One-Pot-LAMP: A promising tool for non-small cell lung cancer diagnosis

Researchers assessed the efficiency of a genetic decoding system for diagnosing non-small cell lung cancer (NSCLC).

16 Mar 2023

The relationship between intestinal microbiome dysbiosis and atherosclerosis

Researchers investigate the impact of intestinal microbiota dysbiosis on atherosclerotic cardiovascular disease incidence.

15 Mar 2023

Point-of-care test identifies patients who may benefit from hypnosis interventions for pain treatment

Hypnosis is an effective treatment for pain for many individuals but determining which patients will benefit most can be challenging. Hypnotizability testing requires special training and in-person evaluation rarely available in the clinical setting.

15 Mar 2023

Study paves way for developing effective ASO therapies for brain diseases with fewer side effects

A promising therapy for a range of brain diseases involves antisense oligonucleotides (ASOs)-;specialized molecules that can modulate RNA and alter protein production-;directly injected into the cerebrospinal fluid, in the space around the brain and spinal cord.

14 Mar 2023

Study highlights poor clinical utility of germline testing in cancer patients of African ancestry

New research in the March 2023 issue of JNCCN-; Journal of the National Comprehensive Cancer Network highlights how the lack of genomic research for people with African ancestry, particularly those from the Sub-Saharan region, is hampering efforts to reduce disparities for people with cancer.

10 Mar 2023

Nucleotide News and Research

Can poor diet and lifestyle behaviors modify genomic susceptibility to impulsivity?

Which functional and structural changes in the brain are associated with blood pressure elevation and cognitive impairment in humans?

Study finds minimal impact of SARS-CoV-2 genome variability on current diagnostic molecular systems

COVID-19 activates endogenous retroviruses within our genome

JPL study uses metagenomic sequencing to monitor microbial burden on spacecraft

Possible pathways of C. auris emergence and the hypothetical role of interspecies transmission

High-resolution mass spectrometric rapid identification of Candida auris

Candida auris infection without epidemiologic links to a prior outbreak

Understanding the structure of CFTR could help design more effective therapies for cystic fibrosis

Pet dogs across the USA are becoming increasingly resistant to benzimidazole treatment

Zoonotic agent Erysipelothrix rhusiopathiae caused mass mortality of harbor porpoises

Higher plasma caffeine concentrations might reduce body fat and type 2 diabetes risk

Study finds shared genetic risk variants across different substance use disorders

Childhood and adolescent obesity: time to act

Research reports spillover of highly pathogenic avian influenza A(H5N1) into marine mammals in the northeastern United States

One-Pot-LAMP: A promising tool for non-small cell lung cancer diagnosis

The relationship between intestinal microbiome dysbiosis and atherosclerosis

Point-of-care test identifies patients who may benefit from hypnosis interventions for pain treatment

Study paves way for developing effective ASO therapies for brain diseases with fewer side effects

Study highlights poor clinical utility of germline testing in cancer patients of African ancestry

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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