Oropharyngeal Cancer News and Research

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New trial platform could help evaluate potential therapies for Parkinson’s disease

Despite 30 years of research, not a single therapy has been found to successfully delay or stop the progression of Parkinson's disease.

6 May 2020

Radiation therapy plays a crucial role in management of OPSCC

HPV-negative UM-SCC4 with and without transfection of HPV E6 oncoprotein, HPV-negative UPCI-SCC-089, and HPV-positive UPCI-SCC-099 cell lines were used in this study.

22 Apr 2020

Racial, socioeconomic disparities found among patients with HPV-positive oropharyngeal cancer

Survival outcomes for HPV-positive oropharyngeal squamous cell carcinoma of the head and neck have made significant gains in recent years, but new research in the February 2020 issue of JNCCN--Journal of the National Comprehensive Cancer Network finds some groups are being left behind.

6 Feb 2020

New plant-based drug shown to help patients with head and neck cancers

In a UCLA-led phase I clinical trial, a new plant-based drug called APG-157 showed signs of helping patients fight oral and oropharyngeal cancers. These cancers are located in the head and the neck.

5 Feb 2020

Using math equations to detect and forecast liver cancer risk

The use of mathematical modeling in the study of biological systems has become a challenging and rewarding field of research as it yields many unknown pieces of information. A new study published online on December 16, 2019, in the journal Proceedings of the National Academy of Science (PNAS).

17 Dec 2019

IMRT and cisplatin treatment meets acceptability criteria for PFS and swallowing-related QOL

Results of the NRG Oncology clinical trial NRG-HN002 indicated that the combination of intensity-modulated radiotherapy (IMRT) and cisplatin was able to meet acceptability criteria for progression-free survival (PFS) and swallowing-related quality of life for patients who have p16-positive, non-smoking-associated oropharyngeal cancer.

18 Sep 2019

Study: Most U.S. adults are unaware that HPV causes anal, penile, and oral cancers

More than 70% of U.S. adults are unaware that human papillomavirus causes anal, penile, and oral cancers, according to an analysis led by researchers at The University of Texas Health Science Center at Houston School of Public Health and published in the current issue of JAMA Pediatrics.

16 Sep 2019

Researchers find characteristics related to better outcomes in HPV-linked oropharyngeal cancer

Using a new blood test that's in development, University of North Carolina Lineberger Comprehensive Cancer Center researchers identified characteristics that could be used to personalize treatment for patients with a type of head and neck cancer linked to HPV infection.

16 Jun 2019

Robotic surgery for oropharyngeal cancer not better than radiation therapy, study finds

In 2012, scientists at Lawson Health Research Institute launched the world's first clinical trial comparing robotic surgery to radiation therapy for the treatment of oropharyngeal cancer (cancer at the back of the throat).

7 Jun 2019

Emerging new type of oral cancer linked to HPV appears to increase in men

An emerging new type of oral cancer in men has increased over the last 15 years. The culprit is human papillomavirus, and key social factors are contributing to its growth.

25 Apr 2019

New biomarker may help better predict outcomes in patients with HPV-related head and neck cancers

By analyzing variations in the level of human papillomavirus (HPV) in head and neck cancers, researchers at The University of Texas MD Anderson Cancer Center have discovered a gene signature associated with treatment response and survival in patients.

10 Jan 2019

New liquid biopsy test confirms remission in patients with HPV-associated oropharyngeal cancer

A highly sensitive blood test that detects minute traces of cancer-specific DNA has been shown to accurately determine whether patients with HPV-related oropharyngeal squamous cell carcinoma are free from cancer following radiation therapy.

23 Oct 2018

Novel blood test shows promise for monitoring HPV-linked head and neck cancer after treatment

A new blood test developed by University of North Carolina Lineberger Comprehensive Cancer Center researchers shows promise for tracking HPV-linked head and neck cancer patients to ensure they remain cancer-free after treatment.

23 Oct 2018

New combination therapy shows potential in treating incurable HPV-related cancers

A tumor-specific vaccine combined with an immune checkpoint inhibitor shrank tumors in one third of patients with incurable cancer related to the human papilloma virus (HPV) in a phase II clinical trial led by investigators at The University of Texas MD Anderson Cancer Center and reported in JAMA Oncology.

28 Sep 2018

Study provides complete picture of HPV virus-head and neck cancer connections

Human papillomavirus is widely known to cause nearly all cases of cervical cancer. However, you might not know that HPV also causes 70 percent of oropharyngeal cancer, a subset of head and neck cancers that affect the mouth, tongue, and tonsils.

12 Sep 2018

Infection rates of high risk oral HPV in England found to be lower than expected

Infection rates of high risk human papillomavirus (HR-HPV) oral infection in England are lower than expected, compared to previous US studies.

20 Aug 2018

UC Davis expert explains about surge in HPV-related throat cancer

Humanpapilloma virus is now the leading cause of certain types of throat cancer. Dr. Michael Moore, director of head and neck surgery at UC Davis and an HPV-related cancer expert, answers some tough questions about the trend and what can be done about it.

1 Aug 2018

Researchers develop artificial intelligence method to help cancer patients worldwide

Before performing radiation therapy, radiation oncologists first carefully review medical images of a patient to identify the gross tumor volume -- the observable portion of the disease. They then design patient-specific clinical target volumes that include surrounding tissues, since these regions can hide cancerous cells and provide pathways for metastasis.

10 May 2018

Researchers aim to accurately identify aggressive oropharyngeal cancers

The Case Western Reserve-led research team will analyze computerized images of tissue samples for patterns which could become "biomarkers," or predictors, for determining relative risk for recurrence in one particularly common type of head and neck cancers.

27 Mar 2018

GIAHC and IPVS partner for first International HPV Awareness Day

The Global Initiative Against HPV and Cervical Cancer that is leading the way in education, empowerment, and eradication of Human Papillomavirus and cervical cancer announces a partnership with the International Papillomavirus Society for HPV Awareness Day, March 4, 2018.

5 Mar 2018