Osteomyelitis News and Research

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Osteomyelitis simply means an infection of the bone or bone marrow. It can be usefully subclassified on the basis of the causative organism (pyogenic bacteria or mycobacteria), the route, duration and anatomic location of the infection.

Researchers review bacteriophage treatment

Researchers presented an overview of bacteriophage treatment, including mechanisms, types, design and applications of bacteriophage therapy.

10 Jan 2023

Spine disease in CRMO patients found to be more common than previously believed

New research presented this week at ACR Convergence 2022, the American College of Rheumatology's annual meeting, shows that spine disease, once considered a rarity in chronic recurrent multifocal osteomyelitis, affects as many as 10-35% of patients and is asymptomatic in one-third.

8 Nov 2022

Genetically predicted height linked to risk for several common health conditions

A large genetic study by the U.S. Department of Veteran Affairs' Million Veteran Program (MVP)) has found that a person's height may affect their risk for several common health conditions in adulthood.

2 Jun 2022

Using the “Wikiguideline” approach to improve the process for establishing medical guidelines

To improve the process for establishing medical guidelines, a group of international researchers are taking a new approach that leans on online collaboration and high-quality data.

10 May 2022

Disparities in major leg amputation and mortality for patients with diabetic foot ulcers

A new study published in JAMA Network Open aimed to identify how intersectionality among race, ethnicity, rurality, and neighborhood disadvantage can result in high risks of major leg amputations and death among Medicare beneficiaries who were hospitalized with diabetic foot ulcers.

24 Apr 2022

Pain neuron-derived peptide protects mice from endotoxic death by enhancing brain ATP production

Sepsis is a high-mortality disease that arises when the body's immune reaction to pathogens causes multi-organ defects.

9 Mar 2022

Study finds reductions in hospital admissions for childhood infections during first year of pandemic

During the first year or so of the covid-19 pandemic, there were dramatic reductions in hospital admissions for common and severe childhood infections in England, most likely due to social distancing measures, school and workplace closures, and travel restrictions, finds a study published by The BMJ today.

13 Jan 2022

Octapharma USA announces FDA approval of cutaquig 16.5% for pediatric PI patients

Octapharma USA today announced the U.S. Food & Drug Administration has approved cutaquig [Immune globulin, Subcutaneous (Human)-hipp, 16.5% Solution] for the treatment of pediatric patients age 2 and older with primary humoral immunodeficiency (PI). The FDA previously approved cutaquig for adults with PI.

7 Dec 2021

Molecular underpinning of chronic bone infection in patients with mycobacterial disease revealed

About a quarter of the world's population is infected with tuberculosis bacteria, according to the World Health Organization, but only about 5 to 10% of those infected will develop symptoms. These pathogens are mycobacteria, which are everywhere, including in chlorine-treated tap water.

8 Sep 2021

Calcified Tissue International announces top 10 most impactful papers of 2019

Calcified Tissue International and Musculoskeletal Research is among the leading peer-reviewed journals publishing original preclinical, translational, and clinical research as well as expert reviews in the bone and musculoskeletal field.

13 Jun 2021

Clinical trial to test existing antibiotic for treating serious S. aureus infections begins

A clinical trial to test the antibiotic dalbavancin for safety and efficacy in treating complicated Staphylococcus aureus (S. aureus) bacteremia has begun.

27 Apr 2021

Researchers identify factors that improve diagnosis of chronic nonbacterial osteomyelitis

Researchers have identified several factors that should help improve the diagnosis of chronic nonbacterial osteomyelitis (CNO), also known as chronic recurrent multifocal osteomyelitis (CRMO).

10 Nov 2020

Study identifies key clinical features of chronic nonbacterial osteomyelitis

New research presented at ACR Convergence, the American College of Rheumatology's annual meeting, identified key clinical features of chronic nonbacterial osteomyelitis (CNO), which leads to an important step toward the development of much-needed classification criteria for a disease that affects children and young adults worldwide.

6 Nov 2020

Combinational therapy with antibiotics and stem cells effectively treats bone infections

Bone infections caused by implants are difficult to treat and usually require a prolonged course of antibiotic treatment.

1 Oct 2020

Research team shines new light on inflammatory cell death regulator

Walter and Eliza Hall Institute researchers have made significant advances in understanding the inflammatory cell death regulatory protein MLKL and its role in disease.

19 Jun 2020

Trusting injection drug users with IV antibiotics at home: It can work

Two mornings a week, Arthur Jackson clears space on half of his cream-colored sofa. He sets out a few rolls of tape and some gauze, then waits for a knock on his front door.

26 Feb 2020

New trial shows how parents can avoid bringing dangerous bacteria into the NICU

For sick or prematurely born babies spending their first days of life in a hospital's neonatal intensive care unit, the soothing voice and gentle touch of a loving parent can have a tremendous impact toward a positive outcome -- that is, unless mom or dad's visit leaves the infant with something extra: a dangerous bacterial infection.

31 Dec 2019

Isolated components of Saussurea have positive effect on bone tissue regeneration

Saussurea controversa is a perennial herbaceous plant that has been traditionally used by the people of the Far East, Siberia, Tibet, and Mongolia to treat liver, kidney, digestive tract, and locomotive diseases. Its dried leaves are sold in pharmacies because their decoction is widely used as a medicine against cold and bronchitis. To understand what substances this plant owes its medicinal properties to, a team of scientists from Siberian State Medical University and Tomsk Polytechnic University extracted individual components from the plant and determined their composition.

3 Dec 2019

Reviews provide overview of advances in the knowledge of focal and sclerotic bone diseases

Recently, extraordinary progress has been made in our understanding of the mechanisms and molecular pathways underlying focal and sclerotic bone diseases, rare disorders which have a strong genetic component.

13 May 2019

New nanomaterial could restore internal structure of damaged bones

Scientists from the National University of Science and Technology "MISIS" developed nanomaterial, which will be able to rstore the internal structure of bones damaged due to osteoporosis and osteomyelitis.

19 Mar 2019