Polymerase News and Research

RSS

Area-level variation in infection fatality ratio in the US COVID-19 pandemic

A new preprint describes the infection fatality ratio, a crucial indicator for planning public health programs and shaping policies.

7 Dec 2021

Method for inactivation and direct RT-qPCR of SARS-CoV-2

Researchers from the University of Edinburgh have been exploring ways to optimize this process further, allowing RT-qPCR to work more efficiently by eliminating one of the key steps.

7 Dec 2021

SARS-CoV-2 Delta saliva viral load 15 times that of the wild type

Researchers hypothesize that a higher viral load of SARS-CoV-2 Delta variant in saliva contributes to its high transmissibility.

6 Dec 2021

Colorimetric detection of SARS-CoV-2 viral RNA by an in vitro transcription/translation assay

This work has emphasized the clinical and translational potential of paper-based biosensors.

6 Dec 2021

COVID-19-recovered patients at an increased risk of developing new-onset mental illness

Research suggests that patients who have recovered from COVID-19 were at an increased risk for developing new-onset mental illness.

6 Dec 2021

A new model linking SARS-CoV-2 viral load to infectiousness may guide further testing strategy

...

5 Dec 2021

Equipment-free handheld microfluidic injection provides visible readout of SARS-CoV-2 detection

In this paper, a group of researchers from Harvard Medical School, McGill University, and Tianjin University describes an on-chip diagnostic technology for the direct detection of SARS-CoV-2 N protein in nasal samples that combines the advantages of hydrodynamic microfluidic filtration and sandwich immunoassay.

5 Dec 2021

Preclinical data shows enhanced T-cell responses & neutralization of SARS-CoV-2 variants with ImmunityBio heterologous vaccination

A new study supports the hypothesis that heterologous vaccination can provide an increased immune response against virus infection, supporting several other studies that have indicated similar events.

5 Dec 2021

Maternal morbidities and outcomes in pregnant women with COVID-19

Researchers aimed to determine whether maternal morbidities and adverse obstetrical outcomes were more frequent in pregnant women with COVID-19.

5 Dec 2021

Risk of COVID-19 hospitalization among children with markers of uncontrolled asthma

The paper describes a national cohort study including all children in Scotland between the ages of 5 and 17 years who were part of the Early Pandemic Evaluation and Enhanced Surveillance of COVID-19 (EAVE II).

3 Dec 2021

Study finds third dose of BNT162b2 or mRNA-1273 is moderately effective against post-vaccination COVID-19 infection

The current study used VHA electronic health records (EHR) to estimate the effectiveness of the booster dose in the USA against post-vaccination COVID-19.

3 Dec 2021

Hybrid immunity provides the highest and most durable immunity against SARS-CoV-2 infection

...

2 Dec 2021

Researchers introduce new method for observing cell interactions

Researchers created a system that allows scientists to ‘log’ a cell’s reactions to external stimuli within the cell’s genetic material.

2 Dec 2021

New bioinformatics method for viral sgRNA analysis

A recent study discusses a bioinformatics method to help identify and explore sgRNAs uncovered in next-generation sequencing data.

2 Dec 2021

Study suggests efficacy of SARS-CoV-2 main protease inhibitors is not compromised in current COVID-19 variants

A new study has focussed on assessing the Mpro mutants of newly emerged SARS-CoV-2 variants.

2 Dec 2021

Natural triterpenoids in licorice found to inhibit SARS-CoV-2

In new studies, researchers concluded that licorice triterpenoids could be candidates for anti-SARS-CoV-2 drug developments.

2 Dec 2021

SARS-CoV-2 infection risks increase with time in fully vaccinated adults

A recent study describes the association between time elapsed since the second dose of the Pfizer-BioNTech BNT162b2 vaccine and risk of COVID-19.

1 Dec 2021

SARS-CoV-2 transmission across age groups makes age-based interventions ineffective

Researchers review critically evaluated the transmission dynamics of SARS-CoV-2 across various ages in metropolitan France.

1 Dec 2021

Plant-derived virus-like particle vaccines against SARS-CoV-2

In a review published in Biotechnology Letters, the authors discuss plant-derived VLP-based vaccines.

1 Dec 2021

Natural COVID-19 infection offers protection from gamma and delta variants of SARS-CoV-2

Natural infection with COVID-19 offered protection from reinfection when the gamma and delta variants predominated, according to a new University of Michigan study that also provides levels of antibodies needed to protect against reinfections.

30 Nov 2021

Polymerase News and Research

Area-level variation in infection fatality ratio in the US COVID-19 pandemic

Method for inactivation and direct RT-qPCR of SARS-CoV-2

SARS-CoV-2 Delta saliva viral load 15 times that of the wild type

Colorimetric detection of SARS-CoV-2 viral RNA by an in vitro transcription/translation assay

COVID-19-recovered patients at an increased risk of developing new-onset mental illness

A new model linking SARS-CoV-2 viral load to infectiousness may guide further testing strategy

Equipment-free handheld microfluidic injection provides visible readout of SARS-CoV-2 detection

Preclinical data shows enhanced T-cell responses & neutralization of SARS-CoV-2 variants with ImmunityBio heterologous vaccination

Maternal morbidities and outcomes in pregnant women with COVID-19

Risk of COVID-19 hospitalization among children with markers of uncontrolled asthma

Study finds third dose of BNT162b2 or mRNA-1273 is moderately effective against post-vaccination COVID-19 infection

Hybrid immunity provides the highest and most durable immunity against SARS-CoV-2 infection

Researchers introduce new method for observing cell interactions

New bioinformatics method for viral sgRNA analysis

Study suggests efficacy of SARS-CoV-2 main protease inhibitors is not compromised in current COVID-19 variants

Natural triterpenoids in licorice found to inhibit SARS-CoV-2

SARS-CoV-2 infection risks increase with time in fully vaccinated adults

SARS-CoV-2 transmission across age groups makes age-based interventions ineffective

Plant-derived virus-like particle vaccines against SARS-CoV-2

Natural COVID-19 infection offers protection from gamma and delta variants of SARS-CoV-2

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Latest News