Prostate News and Research

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Generational differences in men's health habits and concerns revealed

A new national survey by Cleveland Clinic revealed similarities and differences across generations when it comes to men's health.

4 Sep 2024

Researchers develop stable compound for targeted alpha therapy in prostate cancer

Compounds containing astatine-211 (211At) can be used in targeted radiotherapies for prostate cancer, but deastatination in the body remains a significant hurdle.

3 Sep 2024

Recent studies underscore the importance of diet for the prevention of cancer

Recent research highlights the role of diet in cancer prevention, emphasizing Mediterranean and plant-based diets while noting risks associated with red meat.

2 Sep 2024

Study explores link between prostate cancer treatment and Alzheimer’s disease

Researchers at the Medical College of Georgia at Augusta University are searching for a better way to understand why many men with prostate cancer end up with Alzheimer's disease, and whether it's the standard hormone therapy treatment or an overactive immune response that actually contributes to the problem.

29 Aug 2024

The significance of CHEK2 variants in cancer risk assessment

A new editorial was published in Oncotarget's Volume 15 on July 10, 2024, entitled, "Genotype matters: Personalized screening recommendations for germline CHEK2 variants."

27 Aug 2024

Innovations in biomarker detection and personalized medicine for prostate cancer

In a recent comprehensive review published in Cyborg Bionic Systems, researchers led by Keyi Li from the General Hospital of Northern Theater Command in Shenyang, along with international collaborators, detail significant advances in the identification and application of biomarkers for prostate cancer (PCa).

23 Aug 2024

Olaparib effective against BRCA2-mutated prostate cancer

The anti-cancer drug olaparib may be effective in treating biochemically recurrent prostate cancer without accompanying hormone therapy for men who have mutations in genes such as BRCA2, according to results of a phase II clinical trial of 51 patients conducted at the Johns Hopkins Kimmel Cancer Center and three other sites.

23 Aug 2024

The critical role of PGK1 in Parkinson's disease

An enzyme called PGK1 has an unexpectedly critical role in the production of chemical energy in brain cells, according to a preclinical study led by researchers at Weill Cornell Medicine. The investigators found that boosting its activity may help the brain resist the energy deficits that can lead to Parkinson's disease.

21 Aug 2024

Advances in precision medicine enhance cancer immunotherapy

The field of precision medicine, especially in the context of cancer immunotherapy, has seen significant advancements in recent years.

20 Aug 2024

Precision medicine enhances prostate cancer treatment with genetic profiling

Men with metastatic castration-resistant prostate cancer should be treated primarily with second-generation hormone drugs, which offer better treatment response and longer life expectancy than chemotherapy.

20 Aug 2024

Vitamin D deficiency linked to higher cancer mortality

Researchers review how vitamin D deficiency affects the risk of cancer-related mortality.

20 Aug 2024

New RNA molecules in extracellular vesicles could transform cancer diagnosis

Scientists at the Icahn School of Medicine at Mount Sinai have identified a new class of RNAs packed into tiny particles known as extracellular vesicles (EVs) that could revolutionize how cancer and other diseases are diagnosed.

16 Aug 2024

New perspectives on targeting BRAF alterations in cancer

A new research perspective was published in Oncotarget's Volume 15 on July 16, 2024, entitled, "Targeting the multifaceted BRAF in cancer: New directions."

12 Aug 2024

New proteomic clock predicts biological age and major health risks across diverse populations

Study developed a proteomic age clock using plasma proteins to accurately predict biological age and associated health risks, offering a robust tool for forecasting age-related diseases and mortality.

11 Aug 2024

Deep learning model rivals radiologists in detecting prostate cancer on MRI

Researchers assess the power of a fully automated deep learning model to identify of clinically significant prostate cancer.

11 Aug 2024

EZH2's role in cancer progression and therapy explored

Enhancer of zeste homolog 2 (EZH2) is a catalytic subunit of the Polycomb-repressive complex 2 (PRC2), which plays a crucial role in transcriptional repression through the methylation of histone H3 on lysine 27 (H3K27me3).

9 Aug 2024

High BPA levels linked to increased prostate cancer risk in older men

A study in Nutrients found that higher urinary bisphenol A (BPA) levels are linked to increased prostate-specific antigen (PSA) and higher prostate cancer risk in senior American men. This suggests a need for heightened cancer screening, especially in high-risk groups.

8 Aug 2024

MRI scans can predict aggressiveness in intermediate-risk prostate cancer

New Corewell Health™ research suggests an MRI scan can help predict whether patients with intermediate-risk prostate cancer (cancer confined to the entire prostate) may have more aggressive cancer in five years.

7 Aug 2024

Sensory nerves drive breast cancer growth and spread, study reveals

Cancer doesn't grow in a vacuum-;each tumor grows in a particular microenvironment within the body and spreads through a tangled web of vasculature and nerves.

7 Aug 2024

METRNL protein identified as key player in cancer progression

A protein called Meteorin-like (METRNL) in the tumor microenvironment saps energy from T cells, thereby severely limiting their ability to fight cancer, according to new research directed by investigators at the Johns Hopkins University School of Medicine and the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy. Finding ways to block the effects of METRNL signaling on tumor-infiltrating T cells may allow these immune cells to regain the energy necessary to eliminate tumors.

7 Aug 2024