Pulmonary Artery News and Research

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Scientists uncover cellular cause of heart defects in babies born to women with diabetes

When women with diabetes become pregnant, they face not only the typical challenges of pregnancy and impending parenthood, but also a scary statistic: they're five times more likely to have a baby with a congenital heart defect.

30 Nov 2023

Mechanical thrombectomy found to be effective for high-risk pulmonary embolism

New research from the FLASH registry (ClinicalTrials.gov identifier: NCT03761173) shines a light on the effectiveness of large-bore mechanical thrombectomy in managing high-risk pulmonary embolism.

31 Oct 2023

Pulmonary artery catheter use in cardiac surgery patients: Study reveals varied impact on hospital stay and mortality rates

The relationship between pulmonary artery catheter (PAC) use and clinical outcomes in cardiac surgery.

23 Aug 2023

New AI-based screening strategy uses ECG to detect heart defects

Researchers explore the use of artificial intelligence in enhancing the yield of conventional screening for ASDs using 12-lead electrocardiography.

21 Aug 2023

Remote pulmonary artery pressure monitoring improves quality of life, reduces heart failure hospitalizations

The first investigator-initiated study of remote pulmonary artery pressure monitoring has found that it improves quality of life and reduces heart failure hospitalizations in patients with chronic heart failure.

22 May 2023

Mechanical thrombectomy improves symptoms, quality of life in patients with pulmonary embolism

Six month outcomes from the FlowTriever All-Comer Registry for Patient Safety and Hemodynamics (FLASH) registry were presented today as late-breaking clinical research at the Society for Cardiovascular Angiography & Interventions (SCAI) 2023 Scientific Sessions.

19 May 2023

Repression of endothelial TLR3 is a potential mechanism of SARS-CoV-2 infection-associated lung vascular remodeling

Researchers investigated whether endothelial TLR3 insufficiency contributes to lung vascular remodeling induced by SARS-CoV-2.

30 Jan 2023

Women have greater risk of venous thromboembolism than men, research shows

A research team from the Complexity Science Hub and MedUni Vienna analyzed 180,034 patients with diabetes mellitus and found evidence that women are at higher risk of venous thromboembolism than men - particularly during perimenopause.

3 Jan 2023

New catheter leads to a remarkable reduction in pulmonary artery obstruction

A device known as the BASHIR™ Endovascular Catheter (THROMBOLEX, Inc.) significantly reduces the size of blood clots lodged in the pulmonary arteries, leading to improvement in heart function in patients with pulmonary embolism, researchers from the Lewis Katz School of Medicine at Temple University announced in a Late-Breaking Innovation session at the 2022 Transcatheter Cardiovascular Therapeutics (TCT) conference in Boston.

19 Sep 2022

New guidelines recommend earlier detection and treatment of pulmonary hypertension

Earlier detection of pulmonary hypertension in the community and expedited referral of high-risk or complex patients are recommended in the European Society of Cardiology (ESC) and European Respiratory Society (ERS) Guidelines for the diagnosis and treatment of pulmonary hypertension, published online today in European Heart Journal and the European Respiratory Journal.

26 Aug 2022

AI vs. clinical reports for the detection of incidental pulmonary embolus on chest CT

According to ARRS' American Journal of Roentgenology (AJR), an AI tool for detection of incidental pulmonary embolus (iPE) on conventional contrast-enhanced chest CT examinations had high NPV and moderate PPV for detection, even finding some iPEs missed by radiologists.

13 Jul 2022

SARS-CoV-2 spike protein downregulates ACE2 expression

In a new study, researchers observed the downregulation of ACE2 by SARS-CoV-2.

11 Jul 2022

SARS-CoV-2 infection of lung endothelial cells and pulmonary capillary microthrombosis

Researchers evaluated the presence of RNA of SARS-CoV-2 in lung tissue of deceased patients.

4 Jul 2022

Patients with COVID-19 pneumonitis and moderate to severe ARDS treated with sildenafil

A new study published in the British Journal of Anaesthesia aimed to determine whether sildenafil could improve gaseous exchange in patients with COVID-19 ARDS with pulmonary hypertension, RV dysfunction, or both.

17 May 2022

Children's Hospital Los Angeles becomes first in the world to implant cardiac stent in babies

A Children's Hospital Los Angeles team has become the first in the world to implant a cardiac stent that's designed specifically for babies and young children and can be expanded all the way to adult size.

28 Feb 2022

Genome editing in vascular endothelial cells made possible with a powerful new delivery system

Northwestern Medicine scientists developed a unique nanoparticle to deliver genome editing technology, including CRISPR/Cas9, to endothelial cells, which line blood vessel walls.

16 Jan 2022

COVID-19 symptoms found to vary in different immune contexts

In a new study, researchers studied the kinetics of host response to SARS-CoV-2 infection in a Syrian hamster model, tracking disease pathology, viral loads, antibody responses, and inflammatory cytokine production in multiple organs.

11 Jan 2022

Unique nanoparticle can deliver genome editing technology to endothelial cells

The lab of Youyang Zhao, PhD, from Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago developed a unique nanoparticle to deliver genome editing technology, including CRISPR/Cas9, to endothelial cells, which are cells that line blood vessel walls.

4 Jan 2022

Thrombosis with thrombocytopenia syndrome rare but serious adverse event associated with Ad26.COV2.S vaccination

A recent study conducted in the United States has revealed that thrombosis with thrombocytopenia syndrome following adenoviral vector-based coronavirus disease 2019 (COVID-19) vaccination is a rare event.

16 Nov 2021

Simple blood test useful for excluding pulmonary embolism among hospitalized COVID-19 patients

A screening blood test originally validated in seriously ill patients without COVID-19 is still clinically useful for ruling out pulmonary embolism in patients hospitalized with the coronavirus, a University of South Florida Health (USF Health) Morsani College of Medicine research team reports.

26 Oct 2021