Pulmonary Fibrosis News and Research

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Researchers find experimental compound to treat fibrotic diseases

Normal scar tissue forms to heal an internal wound and quietly retreats when the job is done. But in many common diseases - kidney, liver and lung fibrosis -- the scar tissue goes rogue and strangles vital organs. These diseases are largely untreatable and ultimately fatal.

13 Jul 2018

People with type 2 diabetes more likely to suffer from breathlessness, restrictive lung disease

Breathlessness and conditions of restrictive lung disease (RLD), such as pulmonary fibrosis, may be a late complication of type 2 diabetes.

11 Jul 2018

Established lung fibrosis can be reversed using diabetes drug treatment

Researchers at the University of Alabama at Birmingham have shown -; for the first time -; that established lung fibrosis can be reversed using a drug treatment that targets cell metabolism.

2 Jul 2018

Researchers identify culprit that spurs damaging inflammation following heart attack

Scientists have zeroed in on a culprit that spurs damaging inflammation in the heart following a heart attack. The guilty party is a type of immune cell that tries to heal the injured heart but instead triggers inflammation that leads to even more damage.

8 Jun 2018

Lung-on-a-chip technology could streamline drug-testing for pulmonary fibrosis

Developing new medicines to treat pulmonary fibrosis, one of the most common and serious forms of lung disease, is not easy.

25 May 2018

FDA seeks order of permanent injunction to stop two stem cell clinics from marketing stem cell products

The U.S. Food and Drug Administration, in two complaints filed today in federal court, is seeking permanent injunctions to stop two stem cell clinics from marketing stem cell products without FDA approval and for significant deviations from current good manufacturing practice requirements.

10 May 2018

Researchers uncover the cause of scarring in idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is one of the most challenging and frustrating diseases that pulmonologists face.

9 May 2018

Experimental compound reduces destructive inflammation to improve stroke outcome

An experimental compound appears to improve stroke outcome by reducing the destructive inflammation that can continue months after a stroke, scientists report.

20 Apr 2018

CReM researchers optimize process to engineer disease- or patient-specific lung stem cells

The Center for Regenerative Medicine at Boston University and Boston Medical Center has engineered two new categories of lung epithelial cells in vitro using pluripotent stem cells.

12 Apr 2018

Scientists find new molecular target to treat idiopathic pulmonary fibrosis

Scientists searching for a therapy to stop the deadly and mostly untreatable lung disease, idiopathic pulmonary fibrosis (IPF), found a new molecular target that slows or stops the illness in preclinical laboratory tests.

10 Apr 2018

NYU Langone Health surgeons successfully perform first lung transplant procedure

Shortly after receiving final regulatory approval to launch a new lung transplant program, NYU Langone Health surgeons successfully performed the institution's first procedure, giving two new lungs-;and a new lease on life-;to a Brooklyn woman with a complicated form of pulmonary fibrosis.

2 Apr 2018

Dentists mysteriously succumbing to lung disease finds the CDC

The U.S. Centers for Disease Control and Prevention (CDC) has found nine dentists and dental healthcare workers with a progressive lung disease of which seven died. This was published in the CDC’s Morbidity and Mortality Weekly Report yesterday (8th March 2018).

8 Mar 2018

Restoring lipid synthesis could slow progression of pulmonary fibrosis

Pulmonary fibrosis, an ongoing process of scarring that leaves patients chronically short of breath, can progress in severity until the only course of treatment is lung transplant.

6 Mar 2018

Telomere length testing can alter treatment decisions for certain diseases

Research led by Johns Hopkins physicians and scientists shows that a test for measuring the length of DNA endcaps, called telomeres, which has a variability rate of 5 percent, can alter treatment decisions for patients with certain types of bone marrow failure.

27 Feb 2018

ASU researchers uncover crucial step in telomerase enzyme catalytic cycle

Can we stay young forever, or even recapture lost youth? Research from the laboratory of Professor Julian Chen in the School of Molecular Sciences at Arizona State University recently uncovered a crucial step in the telomerase enzyme catalytic cycle.

27 Feb 2018

Researchers develop gene therapy for idiopathic pulmonary fibrosis

Researchers have successfully identified the genetic cause of idiopathic pulmonary fibrosis and have shown success in trials of a new gene therapy.

1 Feb 2018

Researchers use gene therapy that lengthens telomeres to cure pulmonary fibrosis in mice

Idiopathic pulmonary fibrosis is a potentially lethal disease associated with the presence of critically short telomeres, currently lacking effective treatment.

30 Jan 2018

IPF Catalyst Challenge recognizes Owlstone Medical’s Breath Biopsy platform

Owlstone Medical Ltd, a diagnostics company developing a breathalyzer for disease, today announced it is one of the three winners of the global Idiopathic Pulmonary Fibrosis (IPF) Catalyst Challenge, sharing the $1,000.000 (£720,000 GBP) award, each receiving $333,333 (£240,000 GBP).

27 Jan 2018

Reduced activity of transcription factor plays key role in triggering pulmonary fibrosis

To date, the molecular basis of pulmonary fibrosis has been poorly understood. Scientists from the Max Planck Institute for Heart and Lung Research in Bad Nauheim have now shown that reduced activity of the transcription factor FoxO3 plays a key role in the development of the disease.

26 Dec 2017

Treatment with endogenous protein can heal scarring in the lungs

The endogenous protein RAGE, which has usually been negatively associated with chronic inflammation and diabetic complications, plays a major role in the repair of DNA damage - and also appears to heal tissue damaged as a result of accelerated cell senescence.

27 Nov 2017