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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

First images of new gene editing complex which could upgrade CRISPR

Nobel Prize-winning technique used to capture images of a new gene-editing tool that could improve CRISPR-based tools.

19 Dec 2019

A fast, sensitive technique to detect cancer markers brings liquid biopsy closer to clinic

A fast, inexpensive yet sensitive technique to detect cancer markers is bringing researchers closer to a "liquid biopsy" - a test using a small sample of blood or serum to detect cancer, rather than the invasive tissue sampling routinely used for diagnosis.

18 Dec 2019

Suppressing MSUT2 gene may protect people from Alzheimer’s disease

In the wake of recent disappointments over clinical trials targeting amyloid plaque build-up in Alzheimer's disease, researchers are focusing more attention on misfolded tau protein, another culprit in brain diseases that cause dementia.

18 Dec 2019

Study refutes link between increased levels of herpes virus and Alzheimer's disease

Researchers at Baylor College of Medicine report today in the journal Neuron evidence that refutes the link between increased levels of herpes virus and Alzheimer's disease.

18 Dec 2019

Study opens up new treatment possibilities for Wilms' tumor

As an embryo develops, its cells must learn what to do with the thousands of genes they've been equipped with. That's why each cell comes with a detailed gene-expression manual outlining exactly which genes should be switched on, to what extent, and when.

18 Dec 2019

Researchers identify frequent technical bias in data generated by RNA-seq technology

Reproducibility of research data is a major challenge in experimental biology. As data generated by genomic-scale techniques increases in complexity, this concern is becoming more and more worrisome.

18 Dec 2019

Scientists develop computationally inspired method for preclinical study of anxiety

Nearly 40 million people in the U.S. have an anxiety disorder. While treatment options exist, treatment success varies, and many people do not respond to treatment until weeks or months after they begin anti-depressants

18 Dec 2019

Nature’s own gene therapy

A brand-new technique of gene therapy was reported on December 16, 2019, in the journal Nature Biomedical Engineering. The scientists made use of the potential of human cells to produce biological nanoparticles chockful of edited genes, so that they could insert beneficial genes into people suffering from various disease processes.

17 Dec 2019

Using math equations to detect and forecast liver cancer risk

The use of mathematical modeling in the study of biological systems has become a challenging and rewarding field of research as it yields many unknown pieces of information. A new study published online on December 16, 2019, in the journal Proceedings of the National Academy of Science (PNAS).

17 Dec 2019

Researchers identify novel genetic signature with prognostic value for certain breast cancers

Researchers have identified a genetic signature with prognostic value for certain kinds of breast cancer. The discovery also contributes to a better understanding of the molecular mechanisms of pathological angiogenesis, the aberrant proliferation of blood vessels that occurs during cancer and other diseases.

17 Dec 2019

Targeting specific nuclear transport systems may lead to possible therapeutic strategies for cancer

Although less often the focus of cancer research, recent studies have hinted at the possible importance of a type of protein known as nuclear transport receptors.

17 Dec 2019

Researchers identify protein that is key for successful viral DNA uncoating

Viruses have been part of animals and humans for eons. When viruses invade a cell, they can infiltrate the nucleus with their genome and become part of the genome of the infected organism. Viruses transfer their genes between various organisms, as well as between tissues containing well differentiated cells inside a living creature. But how they uncoat their well-packed genes and release them to cause infection is largely unknown.

17 Dec 2019

Genetic mystery of infertility in fruit flies discovered

Researchers have discovered a novel parasitic gene in fruit flies that is responsible for destroying the eggs in the ovaries of their daughters.

17 Dec 2019

New gene therapy has potential to reverse disease processes

Scientists have developed a new gene-therapy technique by transforming human cells into mass producers of tiny nano-sized particles full of genetic material that has the potential to reverse disease processes.

17 Dec 2019

Simple, new test can detect dangerous levels of fluoride in drinking water

Northwestern University synthetic biologists developed a simple, inexpensive new test that can detect dangerous levels of fluoride in drinking water.

16 Dec 2019

Tackling antibiotic resistance head-on with CRISPR

With modern advances in genetic engineering occurring almost every day, the latest discovery concerns antibiotic resistance. Using the powerful gene editor CRISPR, scientists reported the development of a gene-drive system that is 100 times as efficient as other current systems at inactivating a specific bacterial gene responsible for making the bacterium antibiotic-resistant and which is present as multiple copies within the same bacterial cell.

16 Dec 2019

Detection of mouth, throat cancer through saliva testing could become reality

Cancer of the throat and mouth (oropharyngeal cancers, OPC) are common, and are increasing in incidence especially among younger people. However, these are difficult to diagnose as they are not seen either by the patient or during routine medical examinations.

15 Dec 2019

Molecular subtyping of bladder tumors outperformed by standard pathology tests

While trying to develop a comparatively easy, inexpensive way to give physicians and their patients with bladder cancer a better idea of likely outcome and best treatment options, scientists found that sophisticated new subtyping techniques designed to do this provide no better information than long-standing pathology tests.

14 Dec 2019

Horizon Discovery adds predesigned synthetic single guide RNA to its product range

Horizon Discovery Group plc, a global leader in the application of gene editing and gene modulation technologies, today announced the addition of predesigned synthetic single guide RNA (sgRNA) to its product range.

From Revvity 13 Dec 2019

Precision epigenome editing can repair genetic syndrome of intellectual disability

Using a targeted gene epigenome editing approach in the developing mouse brain, Johns Hopkins Medicine researchers reversed one gene mutation that leads to the genetic disorder WAGR syndrome, which causes intellectual disability and obesity in people.

13 Dec 2019

RNA News and Research

Further Reading

First images of new gene editing complex which could upgrade CRISPR

A fast, sensitive technique to detect cancer markers brings liquid biopsy closer to clinic

Suppressing MSUT2 gene may protect people from Alzheimer’s disease

Study refutes link between increased levels of herpes virus and Alzheimer's disease

Study opens up new treatment possibilities for Wilms' tumor

Researchers identify frequent technical bias in data generated by RNA-seq technology

Scientists develop computationally inspired method for preclinical study of anxiety

Nature’s own gene therapy

Using math equations to detect and forecast liver cancer risk

Researchers identify novel genetic signature with prognostic value for certain breast cancers

Targeting specific nuclear transport systems may lead to possible therapeutic strategies for cancer

Researchers identify protein that is key for successful viral DNA uncoating

Genetic mystery of infertility in fruit flies discovered

New gene therapy has potential to reverse disease processes

Simple, new test can detect dangerous levels of fluoride in drinking water

Tackling antibiotic resistance head-on with CRISPR

Detection of mouth, throat cancer through saliva testing could become reality

Molecular subtyping of bladder tumors outperformed by standard pathology tests

Horizon Discovery adds predesigned synthetic single guide RNA to its product range

Precision epigenome editing can repair genetic syndrome of intellectual disability

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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