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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Study compares library preparation and sequencing platforms for single-cell RNA-sequencing

Researchers from University of Southern Denmark, Wellcome Sanger Institute and BGI, today published a study in the journal Genome Biology comparing the library preparation and sequencing platforms for single-cell RNA-sequencing.

9 Apr 2019

UTMB receives grant to combat highly-lethal hemorrhagic fever viruses

The University of Texas Medical Branch at Galveston, Profectus Biosciences, Vanderbilt University Medical Center, Mapp Biopharmaceutical and Genevant Sciences Corp. have been awarded up to $35 million to advance the development of rapid-acting vaccines and broad-spectrum treatments of the highly-lethal hemorrhagic fever viruses Ebola and Marburg.

9 Apr 2019

FDA approves two-drug complete regimen for previously untreated HIV-infected adults

The U.S. Food and Drug Administration today approved Dovato (dolutegravir and lamivudine), as a complete regimen for the treatment of human immunodeficiency virus type 1 (HIV-1) infection in adults with no antiretroviral treatment history and with no known or suspected substitutions associated with resistance to the individual components of Dovato.

9 Apr 2019

Study of pregnant women with lupus identifies early indicators of pregnancy complications

A study of pregnant women with systemic lupus erythematosus has identified early changes in the RNA molecules present in the blood that could be used to determine the likelihood of them developing preeclampsia.

8 Apr 2019

New clinical trials to investigate combination immunotherapy for treating advanced cancers

City of Hope physician-scientists recently opened two clinical trials to investigate a combination of cytokines and immunotherapy that may be able to transform nearly-impossible-to-treat cancer into a disease that can be corralled into remission.

8 Apr 2019

A gene regulatory multi-tool plays key role in unjamming the genome after DNA damage

A protein complex that is involved in nearly every step in the regulatory control of gene expression in cells has now been shown also to play a key role in clearing potential traffic jams in the production of RNA.

5 Apr 2019

UMSOM's Institute for Genome Sciences receives $17.5 million grant for infectious disease research

The Institute for Genome Sciences at the University of Maryland School of Medicine was awarded $17.5 million from the National Institute of Allergy and Infectious Diseases to fund the IGS Genome Center for Infectious Diseases for another five years.

5 Apr 2019

Research unravels possible factor for female bias in lupus

The autoimmune disease lupus, which can cause fatigue, a facial rash, and joint pain, strikes females far more often than males. Eight-five percent of people with lupus are female, and their second X chromosome seems partly to blame.

5 Apr 2019

Study finds cellular protein as a 'gas pump attendant' of cancer development

The cells which make up our body vary significantly. A liver cell does not look like a muscle cell and each has a unique function. This is because liver cells produce the proteins that characterize them, and muscle cells do the same.

1 Apr 2019

Potential drug targets cause of adult-onset muscular dystrophy

People diagnosed with myotonic dystrophy type 1 have difficulty unclenching muscles due to a genetic defect that generates toxic material within their cells.

1 Apr 2019

Designer organelles in living mammalian cells can build synthetic proteins

A research team led by biophysical chemist Professor Edward Lemke has engineered a designer organelle in a living mammalian cell in a new complex biological translation process. The created membraneless organelle can build proteins from natural and synthetic amino acids carrying new functionalities.

30 Mar 2019

Cellular mechanism that connects smoking during pregnancy and baby’s obesity risk identified

Using foreskin tissue from newborn circumcisions, a group of researchers have identified a potential cellular mechanism that connects a mother's smoking while pregnant with an increased risk of offspring obesity later in life.

30 Mar 2019

Pediatric Cell Atlas needed for better understanding of children’s health and illnesses

Research efforts to comprehensively map adult human cells are in progress. But in a Perspective publishing March 28 in the journal Developmental Cell, researchers argue that there is a need to map children’s cells with the same level of granularity.

29 Mar 2019

Single lineage of stem cells contributes to lifelong hippocampal neurogenesis in mice

Scientists once thought that mammals entered adulthood with all of the neurons they would ever have, but studies from the 60s found that new neurons are generated in certain parts of the adult brain and pioneering studies from the 90s helped identify their origins and function.

29 Mar 2019

Walnut consumption could change gene expression in pathologically-confirmed breast cancers

New research from Marshall University links walnut consumption as a contributing factor that could suppress growth and survival of breast cancers.

29 Mar 2019

Promising new way to thwart tricky Mtb pathogen

Tuberculosis, an ancient and notoriously difficult disease to treat, has killed millions through the course of human history; and the antibiotics that have been used to fight the disease in recent history are becoming less and less effective.

29 Mar 2019

UTM researchers uncover 'master pacemaker' for biological clocks

What makes a biological clock tick? According to a new study from U of T Mississauga, the surprising answer lies with a gene typically associated with stem and cancer cells.

28 Mar 2019

Low-dose radiation therapy may increase uptake of therapeutic nanoparticles by brain tumors

A new study led by Massachusetts General Hospital (MGH) investigators finds that radiation therapy may increase the uptake of therapeutic nanoparticles by glioblastomas, raising the possibility of using both growth-factor-targeted and immune-system-based therapies against the deadly brain tumor.

28 Mar 2019

Garvan researchers develop more accurate method to diagnose cancer subtypes

Developed by researchers at the Garvan Institute of Medical Research, this potential diagnostic method screens a cancer sample for 'fusion genes', estimated to be linked to one in five cancers, and may provide a more accurate snapshot of rearranged DNA found in cancer.

28 Mar 2019

C-Path and Japan's PMDA join forces on first-of-its-kind biomarker project

Critical Path Institute announced today that a formal consultation between its Predictive Safety Testing Consortium and Japan's Pharmaceuticals and Medical Devices Agency has resulted in an agreement on a first-of-its-kind approach to compare the levels of eight novel urinary kidney safety biomarkers in healthy Japanese volunteers to data collected on these same biomarkers in healthy Western volunteers in a bridging study.

27 Mar 2019

RNA News and Research

Further Reading

Study compares library preparation and sequencing platforms for single-cell RNA-sequencing

UTMB receives grant to combat highly-lethal hemorrhagic fever viruses

FDA approves two-drug complete regimen for previously untreated HIV-infected adults

Study of pregnant women with lupus identifies early indicators of pregnancy complications

New clinical trials to investigate combination immunotherapy for treating advanced cancers

A gene regulatory multi-tool plays key role in unjamming the genome after DNA damage

UMSOM's Institute for Genome Sciences receives $17.5 million grant for infectious disease research

Research unravels possible factor for female bias in lupus

Study finds cellular protein as a 'gas pump attendant' of cancer development

Potential drug targets cause of adult-onset muscular dystrophy

Designer organelles in living mammalian cells can build synthetic proteins

Cellular mechanism that connects smoking during pregnancy and baby’s obesity risk identified

Pediatric Cell Atlas needed for better understanding of children’s health and illnesses

Single lineage of stem cells contributes to lifelong hippocampal neurogenesis in mice

Walnut consumption could change gene expression in pathologically-confirmed breast cancers

Promising new way to thwart tricky Mtb pathogen

UTM researchers uncover 'master pacemaker' for biological clocks

Low-dose radiation therapy may increase uptake of therapeutic nanoparticles by brain tumors

Garvan researchers develop more accurate method to diagnose cancer subtypes

C-Path and Japan's PMDA join forces on first-of-its-kind biomarker project

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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