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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Cervical microbiome may influence HPV infection more than previously thought

Infections with a Human Papillomavirus cause 99 percent of cervical cancer cases, and the disease's first sign is often the appearance of precancerous lesions on a woman's cervix. But bacteria may play an important role, too.

19 Feb 2019

Unique gene therapy approach paves new way to tackle rare, inherited diseases

Nonsense mutations are single-letter errors in the genetic code that prematurely halt the production of critical proteins. These unfinished proteins are unable to function normally, and nonsense mutations cause 10-15 percent of all inherited genetic diseases, including Duchenne muscular dystrophy, spinal muscular atrophy, cystic fibrosis and polycystic kidney disease.

19 Feb 2019

Researchers create new map of the brain's own immune system

A team of researchers under the direction of the Medical Center - University of Freiburg has created an entirely new map of the brain's own immune system in humans and mice.

19 Feb 2019

Specialized lung cells appear in the developing fetus much earlier than previously thought

Specialized lung cells appear in the developing fetus much earlier than scientists previously thought. A new animal study reports how cells that become alveoli, the tiny compartments in which gas exchange occurs in the lung, begin their specialized roles very early in prenatal life.

19 Feb 2019

Fetal signaling pathways may offer future opportunities to treat lung damage

Specialized lung cells appear in the developing fetus much earlier than scientists previously thought. A new animal study published this week in the Proceedings of the National Academy of Sciences reports how cells that become alveoli, the tiny compartments in which gas exchange occurs in the lung, begin their specialized roles very early in prenatal life.

18 Feb 2019

New protocol can help identify febrile infants at low risk for serious bacterial infections

A national research team led by UC Davis Health clinicians and researchers from the University of Michigan, Nationwide Children's Hospital and Columbia University, has derived and validated a new protocol for emergency departments that can determine which infant patients with fevers, age 60 days or younger, are at low risk of significant bacterial infections.

18 Feb 2019

New method for improved visualization of single-cell RNA- sequencing data

Like going from a pinhole camera to a Polaroid, a significant mathematical update to the formula for a popular bioinformatics data visualization method will allow researchers to develop snapshots of single-cell gene expression not only several times faster but also at much higher-resolution.

15 Feb 2019

Novel approach uses small amounts of tissue to quantify PD-L1 expression levels in tumors

Immune checkpoint inhibitors, such as the anti-PD-1 antibody pembrolizumab, have become important tools for managing non-small-cell lung cancer.

14 Feb 2019

Promega launches Maxwell RSC miRNA Plasma and Serum Kit

Promega Maxwell RSC miRNA plasma and serum kit, introduced this week, provides quick, automated miRNA purification for oncology and translational researchers.

From Promega Corporation 13 Feb 2019

NIH scientists zero in on genes associated with AMD

National Eye Institute scientists led a collaborative study and zeroed in on genes associated with age-related macular degeneration, a leading cause of vision loss and blindness among people age 65 and older.

12 Feb 2019

Research sheds light on how motor enzyme can promote genome integrity

Approximately one per cent of each organism's genome encodes helicases. Helicases are mostly known as motor enzymes that can unwrap double-stranded DNA by use of energy.

11 Feb 2019

Scientists develop novel way with genome sequences to study widespread form of malaria

Scientists at the Institute of Genome Sciences at the University of Maryland School of Medicine have developed a novel way with genome sequences to study and better understand transmission, treat and ultimately eradicate Plasmodium vivax, the most widespread form of malaria. P. vivax is a single-celled transmitted by mosquitoes.

11 Feb 2019

Bariatric surgery changes the way our body senses food

How bariatric surgery helps people with obesity and diabetes is related to changes in the way the gut senses food and nutrients after the operation, researchers report February 5 in the journal Cell Reports.

8 Feb 2019

IDT supports innovative synthetic biology start-ups with grant program

Integrated DNA Technologies’ Synthetic Biology Start-up Grant Program has once again benefited innovative start-ups in their missions to impact sustainable manufacturing, human health, and/or humanitarian causes.

From Integrated DNA Technologies 8 Feb 2019

RNAs are involved in protein aggregation and neurodegenerative diseases, research reveals

New research reveals RNAs, which are crucial for cells to produce proteins, are also involved in protein aggregation, where proteins do not fold properly and 'clump' together into aggregates. If cells cannot clear these away, they become toxic and prevent cells working properly.

8 Feb 2019

New DNA-based nanomachines can be used for gene therapy of cancer

Scientists from ITMO in collaboration with their international colleagues proposed new DNA-based nanomachines that can be used for gene therapy of cancer.

8 Feb 2019

Study shows precision medicines could aid more breast cancer patients via RNA-targeting

When women or men receive the worrisome diagnosis of breast cancer, that news comes with an important piece of information, namely, whether their cancer is HER2-positive or HER2-negative.

8 Feb 2019

New research on viral biology could lead to efficient vaccines against leishmaniasis

New research from McGill University has found that a virus infecting the Leishmania parasite spreads by exploiting a mechanism used for cell-to-cell communication, a discovery that could pave the way to new vaccines against infections that cause severe disfiguration.

8 Feb 2019

Binge drinking in adolescence causes lasting changes in emotional center of brain

Binge drinking in adolescence has been shown to have lasting effects on the wiring of the brain and is associated with increased risk for psychological problems and alcohol use disorder later in life.

7 Feb 2019

New acute porphyria treatment shows promising results in clinical study

Acute porphyria is a group of uncommon diseases that can cause severe, potentially life-threatening attacks of abdominal pain, nausea, vomiting and paralysis. Liver transplantation is currently the only effective treatment available for the most seriously afflicted patients.

7 Feb 2019

RNA News and Research

Further Reading

Cervical microbiome may influence HPV infection more than previously thought

Unique gene therapy approach paves new way to tackle rare, inherited diseases

Researchers create new map of the brain's own immune system

Specialized lung cells appear in the developing fetus much earlier than previously thought

Fetal signaling pathways may offer future opportunities to treat lung damage

New protocol can help identify febrile infants at low risk for serious bacterial infections

New method for improved visualization of single-cell RNA- sequencing data

Novel approach uses small amounts of tissue to quantify PD-L1 expression levels in tumors

Promega launches Maxwell RSC miRNA Plasma and Serum Kit

NIH scientists zero in on genes associated with AMD

Research sheds light on how motor enzyme can promote genome integrity

Scientists develop novel way with genome sequences to study widespread form of malaria

Bariatric surgery changes the way our body senses food

IDT supports innovative synthetic biology start-ups with grant program

RNAs are involved in protein aggregation and neurodegenerative diseases, research reveals

New DNA-based nanomachines can be used for gene therapy of cancer

Study shows precision medicines could aid more breast cancer patients via RNA-targeting

New research on viral biology could lead to efficient vaccines against leishmaniasis

Binge drinking in adolescence causes lasting changes in emotional center of brain

New acute porphyria treatment shows promising results in clinical study

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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