RNA News and Research

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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Research shows long non-coding RNAs regulate circadian clocks

Researchers at UT Southwestern Medical Center have found a new way that internal body clocks are regulated by a type of molecule known as long non-coding RNA.

19 Aug 2014

Researchers identify microRNAs that differentiate male and female fruit flies

Men and women differ in plenty of obvious ways, and scientists have long known that genetic differences buried deep within our DNA underlie these distinctions. In the past, most research has focused on understanding how the genes that encode proteins act as sex determinants.

19 Aug 2014

Globavir plans to seek approval, launch novel drug for treatment of Ebola infection

Globavir Biosciences, Inc., a biotechnology company developing therapeutics to treat infectious diseases, has announced intentions to develop its lead drug candidate, GBV006, for the treatment of the current Ebola Virus outbreak in West Africa. Globavir will seek approval for the use of GBV006, a combination of Food and Drug Administration approved drugs, through an established compassionate use regulatory pathway.

19 Aug 2014

Researchers reveal how early changes in DNA methylation involved in Alzheimer's disease

A new study led by researchers at Brigham and Women's Hospital (BWH) and Rush University Medical Center, reveals how early changes in brain DNA methylation are involved in Alzheimer's disease.

18 Aug 2014

Researchers now have a clear picture of bacterial immune system

Bacteria's ability to destroy viruses has long puzzled scientists, but researchers at the Johns Hopkins Bloomberg School of Public Health say they now have a clear picture of the bacterial immune system and say its unique shape is likely why bacteria can so quickly recognize and destroy their assailants.

15 Aug 2014

Research offers promise for personalized RNA combination therapies to treat lung cancer

Small RNA molecules, including microRNAs (miRNAs) and small interfering RNAs (siRNAs), offer tremendous potential for new therapeutic agents to inhibit cancer cell growth. However, delivering these small RNAs to solid tumors remains a significant challenge, as the RNAs must target the correct cells and avoid being broken down by enzymes in the body.

15 Aug 2014

New therapeutic strategy to combat common genetic risk factor for ALS, FTD

A team of researchers at Mayo Clinic and The Scripps Research Institute in Florida have developed a new therapeutic strategy to combat the most common genetic risk factor for the neurodegenerative disorders amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease) and frontotemporal dementia (FTD).

15 Aug 2014

HDAC inhibitors may also be effective against kidney stones

Anyone who has suffered from kidney stones is keenly aware of the lack of drugs to treat the condition, which often causes excruciating pain.

15 Aug 2014

Researchers find method to repair gene mutation causing autoimmune deficiency disease

Researchers at Karolinska Institutet in Sweden have found a method to repair the gene mutation causing agammaglobulinemia, an autoimmune deficiency disease that almost exclusively affects boys and in which the body lacks the ability to produce immunoglobulins (gamma globulin).

14 Aug 2014

Combination of NASBA and real-time qPCR detects aspergillosis with 100% accuracy

The fungal infection invasive aspergillosis (IA) can be life threatening, especially in patients whose immune systems are weakened by chemotherapy or immunosuppressive drugs. Despite the critical need for early detection, IA remains difficult to diagnose.

14 Aug 2014

Leica Biosystems, ACD co-market RNAscope LS ISH assays and BOND RX instrument

Leica Biosystems and Advanced Cell Diagnostics, Inc. (ACD) have announced the co-marketing of ACD's RNAscope® LS ISH assays with Leica Biosystems' BOND RX research staining platform.

From Advanced Cell Diagnostics 13 Aug 2014

Findings may lead to better ways for preventing gum disease, diabetes and Crohn's disease

Bacteria inside your mouth drastically change how they act when you're diseased, according to research using supercomputers at the Texas Advanced Computing Center.

13 Aug 2014

Identifying epigenetic markers in cancer cells could improve patient treatment

Scientists have known for decades that cancer can be caused by genetic mutations, but more recently they have discovered that chemical modifications of a gene can also contribute to cancer.

13 Aug 2014

New approach to knocking out parasite's genes

Plasmodium falciparum, the parasite that causes malaria, has proven notoriously resistant to scientists' efforts to study its genetics.

12 Aug 2014

Researchers discover how immunosensory system attacks viruses on a molecular level

Our immunosensory system detects virus such as influenza via specific characteristics of viral ribonucleic acid. Previously, it was unclear how the immune system prevents viruses from simply donning molecular camouflage in order to escape detection.

11 Aug 2014

GW researcher awarded grant to develop a model system to study PN infection

According to a recent World Health Organization report of the leading causes of death worldwide, one-third of all deaths are due to infectious and parasitic diseases. There are currently no vaccines for parasitic nematode (PN), or worm infections in humans, and development of new drugs and vaccines will stall until researchers have a better understanding of PN biology.

11 Aug 2014

ISO 13485:2003 certification for Advanced Cell Diagnostics

Advanced Cell Diagnostics, Inc. (ACD), a global technology and market leader in in situ nucleic acid detection for life science research and clinical diagnostics, has been granted ISO 13485:2003 certification, an international quality standard for medical devices, paving a path for ACD to launch its CE marked diagnostic tests in Europe.

From Advanced Cell Diagnostics 11 Aug 2014

Researchers discover cardiac molecule that could provide key to treating, preventing heart failure

Researchers have discovered a previously unknown cardiac molecule that could provide a key to treating, and preventing, heart failure.

11 Aug 2014

Isoform: New protein offers novel therapeutic approach for patients with DMD

Scientists have discovered a new form of dystrophin, a protein critical to normal muscle function, and identified the genetic mechanism responsible for its production.

11 Aug 2014

Scientists analyze genetic characteristics of cancers using multiple genomic technology platforms

New research partly led by UC San Francisco-affiliated scientists suggests that one in 10 cancer patients would be more accurately diagnosed if their tumors were defined by cellular and molecular criteria rather than by the tissues in which they originated, and that this information, in turn, could lead to more appropriate treatments.

8 Aug 2014

RNA News and Research

Further Reading

Research shows long non-coding RNAs regulate circadian clocks

Researchers identify microRNAs that differentiate male and female fruit flies

Globavir plans to seek approval, launch novel drug for treatment of Ebola infection

Researchers reveal how early changes in DNA methylation involved in Alzheimer's disease

Researchers now have a clear picture of bacterial immune system

Research offers promise for personalized RNA combination therapies to treat lung cancer

New therapeutic strategy to combat common genetic risk factor for ALS, FTD

HDAC inhibitors may also be effective against kidney stones

Researchers find method to repair gene mutation causing autoimmune deficiency disease

Combination of NASBA and real-time qPCR detects aspergillosis with 100% accuracy

Leica Biosystems, ACD co-market RNAscope LS ISH assays and BOND RX instrument

Findings may lead to better ways for preventing gum disease, diabetes and Crohn's disease

Identifying epigenetic markers in cancer cells could improve patient treatment

New approach to knocking out parasite's genes

Researchers discover how immunosensory system attacks viruses on a molecular level

GW researcher awarded grant to develop a model system to study PN infection

ISO 13485:2003 certification for Advanced Cell Diagnostics

Researchers discover cardiac molecule that could provide key to treating, preventing heart failure

Isoform: New protein offers novel therapeutic approach for patients with DMD

Scientists analyze genetic characteristics of cancers using multiple genomic technology platforms

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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