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Virginia Tech researchers develop new drug design framework to fight COVID-19

As the COVID-19 pandemic scattered and isolated people, researchers across Virginia Tech connected for a data-driven collaboration seeking improved drugs to fight the disease and potentially many other illnesses.

19 Oct 2023

AI-powered patient triage platform predicts COVID-19 severity and length of hospitalization

A team of researchers from Yale University and other institutions globally has developed an innovative patient triage platform powered by artificial intelligence (AI) that the researchers say is capable of predicting patient disease severity and length of hospitalization during a viral outbreak.

29 Aug 2023

Differences in immune responses to IL-6 inhibition therapy between male and female COVID-19 patients

Researchers investigated whether anti‑interleukin 6 monoclonal antibodies were related to heterogenous treatment effects between male and female COVID-19 patients.

24 Aug 2023

Proxalutamide shows promise as potential COVID-19 treatment

At the outset of the COVID pandemic, men appeared to suffer higher rates of severe illness and death, leading researchers to suspect a link between androgen receptors-;which bind to hormones like testosterone--and SARS-CoV-2 viral infection.

18 Aug 2023

Potential of COVID-19 convalescent plasma for future monoclonal antibodies against severe SARS-CoV-2 inflammation

Researchers report that convalescent plasma treatment is most effective in treating hospitalized COVID-19 patients.

17 Aug 2023

Intranasal inoculation study sheds light on nasal and systemic immune responses to SARS-CoV-2

Study reveals the events accompanying the COVID-19 infection cascade in the nasal mucosa and free circulation

1 Aug 2023

Unveiling the key defender: PLSCR1 identified as a potent anti-SARS-CoV-2 factor in COVID-19 immunity

Researchers identified the anti-SARS-CoV-2 function of phospholipid scramblase 1 (PLSCR1).

14 Jul 2023

IL-9 identified as contributor to viral spread and airway inflammation in COVID-19

Researchers used a K18-hACE2 transgenic (ACE2.Tg) mouse model to demonstrate that interleukin-9 (IL-9).

13 Jul 2023

Two anti-inflammatory drugs reduce deaths in severe COVID-19 patients

Two anti-inflammatory drugs, abatacept and infliximab, reduced deaths among patients hospitalized with severe COVID-19, according to a national study led by Washington University School of Medicine in St. Louis. William G. Powderly, MD, (right) who led the large clinical trial, discusses patient conditions with Maanasi Samant, MD, in the intensive care unit at Barnes-Jewish Hospital, one of the major trial sites, during the COVID-19 pandemic.

10 Jul 2023

Prior exposure to air pollutants and black carbon load predicts outcomes in hospitalized COVID-19 patients

Researchers investigated whether black carbon particles in the blood increased COVID-19 severity.

23 Jun 2023

Molecular insights into long COVID: serum proteome reveals dominant signaling pathways

Researchers examined the serum proteome of unvaccinated adults who had PASC.

15 Jun 2023

Using heart and lung stem cells to better understand how COVID-19 impacts different organs

Researchers have used heart and lung stem cells infected with the virus that causes COVID-19 to better understand how the disease impacts different organs, paving the way for more targeted treatments.

13 Jun 2023

When COVID meets Candida: exploring the alarming surge of C. auris in Israel

CDC reports an outbreak involving Candida auris (C. auris) in Israel.

13 Jun 2023

Common diabetes drug prevents the development of long COVID, study finds

In a new study published in The Lancet Infectious Diseases, University of Minnesota researchers found that metformin, a drug commonly used to treat diabetes, prevents the development of long COVID.

9 Jun 2023

Nanoparticles take aim at COVID-19 with lysosome-targeted delivery

Researchers discuss the use of endo-lysosome-targeted nanoparticles for delivering antiviral therapy to treat coronavirus infections.

15 May 2023

Anticoronavirals: the development of COVID-19 therapies and the challenges that remain

Researchers highlighted the pace of development of COVID-19 therapies during the pandemic and the challenges that hinder the widespread availability of anticoronavirals.

8 May 2023

Does stress increase biological age?

Researchers evaluated stress-induced biological age (BA) changes among mice and humans.

4 May 2023

The Wonder of DNA: Reflections from Dr. Francis Collins on the 20th Anniversary of the Human Genome Project

To highlight how far the field of genetics has come, we spoke with Dr. Francis Collins, the leader of the Human Genome Project about his incredible career in genetics.

25 Apr 2023

Early use of dexamethasone associated with reduced mortality in hospitalized COVID-19 requiring breathing support

In a recent study published in the journal JAMA Network Open, researchers examined the clinical use of dexamethasone for hospitalized patients with coronavirus disease 2019 (COVID-19) respiratory illness and explored the heterogeneity of treatment outcomes across different subgroups.

19 Apr 2023

An extremely rare case report of rebound multi-system inflammatory syndrome in children

Researchers described the case report of an infant boy experiencing rebound MIS-C.

12 Apr 2023