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Study reports low risk for COVID-19 in Emergency Medical Service personnel exposed to aerosol-generating procedures

The U.S. Centers for Disease Control and Prevention (CDC) reports that emergency medical service personnel exposed to aerosol-generating procedures (AGP) on COVID-19 patients are generally at low risk of infection. The findings, published in CDC’s Emerging Infectious Diseases, support clinical strategies that maintain established and evidence-based practices for emergency conditions.

13 Jul 2021

Patient characteristics including demographic factors and comorbidities can accurately predict the outcome of COVID-19 infection severity

New machine learning models incorporating COVID-19 infection data show that patient demography is a key predictor of infection outcome.

13 Jul 2021

Review details clinical signs of SARS-CoV-2 infection in domestic and wild cats

Now, a new systematic review has been published in the journal Animals that focuses on the clinical symptoms in felines diagnosed with SARS-CoV-2 worldwide.

13 Jul 2021

Natural compound 'pheophorbide a' demonstrates robust antiviral activity against SARS-CoV-2 in vitro

A team of scientists from France has recently demonstrated photosensitive antiviral activity of the natural compound pheophorbide a (Pba) against a broad range of enveloped viruses, including coronaviruses.

12 Jul 2021

Real-world evidence SARS-CoV-2 mRNA vaccines work and help prevent worst outcomes

Researchers in the United States have conducted a study demonstrating the real-world effectiveness of the Pfizer-BioNTech BNT162b2 and Moderna mRNA-1273 vaccines at preventing hospitalizations due to coronavirus disease 2019 (COVID-19).

12 Jul 2021

Study sheds light on immune processes involved in long COVID

Researchers in the United States have provided important insights into the immune processes that may be associated with post-acute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection – also referred to as long COVID (coronavirus disease 2019).

12 Jul 2021

Nose drops of modified 'friendly' bacteria offer protection against meningitis

A world-first trial has shown that nose drops of modified 'friendly' bacteria protect against meningitis.

12 Jul 2021

New research examines the elimination of the B.1.362 + L452R variant in Israel

Is it possible to completely get rid of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants? New research led by Neta S. Zuckerman of Sheba Medical Center in Israel suggests it’s possible. Their report details the upsurge of a B.1.362 variant harboring the L452R mutation that eventually disappeared due to vaccination efforts and the presence of more robust variants.

12 Jul 2021

Millions of COVID-19 cases went undetected in the first six months of the pandemic, finds study

A new report published in the journal Science Translational Medicine estimates that potentially 16.8 million Americans were infected but not officially diagnosed with SARS-CoV-2 by July 2020. In addition, the results suggest there were nearly five undetected coronavirus cases for every diagnosed coronavirus infection in the first six months of the pandemic.

12 Jul 2021

Chemicals found in common household products increase asthma risk

Commonly-used household products should carry a warning that they increase the risk of asthma, according to a new evidence review.

12 Jul 2021

Review of scientific evidence supports zoonotic origin for SARS-CoV-2 with zero biological evidence for laboratory leak scenario

Recently, an international team of biologists, led by professors from the University of Sydney and the University of Edinburgh, critically reviewed currently available scientific evidence that may throw some light on the origin of the virus that causes COVID-19.

12 Jul 2021

Scientists identify novel entry receptors for SARS-CoV-2

Scientists from the Northeastern University, China, and University of Michigan, USA, have recently identified five potential entry receptors for SARS-CoV-2. These receptors specifically express in SARS-CoV-2-infected cells and have a high binding affinity for the viral spike protein.

12 Jul 2021

mRNA-based COVID-19 vaccine CV07050101 demonstrates limited immunogenicity in non-human primates

Scientists from the US and Germany have recently evaluated the efficacy of an mRNA-based COVID-19 vaccine candidate, CV07050101, in inducing humoral and cellular immune responses in non-human primates. The study reveals that prime-boost immunization with the vaccine candidate induces only limited immunity against SARS-CoV-2.

12 Jul 2021

Composition and structure of nasopharyngeal microbiome relate to COVID-19 disease severity

Breathing treatments are provided to hospitalized COVID-19 patients. In this study, the researchers examined the community composition in relation to three attributes - COVID-19 status, breathing assistance, and antibiotic use. This study is published in the journal, Applied Microbiology.

12 Jul 2021

What is behind the inconsistent results of COVID-19 clinical trials?

“Most clinical studies of antiviral drugs for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) have failed to observe a statistically significant effect, which may be due to poor designs of clinical trials.”

12 Jul 2021

SARS-CoV-2 mRNA vaccine efficacy reduced in patients with CD20-B-cell depleting treatment history

Researchers from Switzerland recently investigated humoral and cell-mediated immune responses to mRNA-based vaccines in patients undergoing treatment with CD20-B-cell depleting agents for autoimmune diseases, transplantation, or malignancy.

12 Jul 2021

Socioeconomic inequities and structural racism are neglected pieces of SARS-CoV-2 transmission networks

A recent perspective article published in the prestigious journal Science highlights how the use of network-driven strategies for adequately informing rapidly emergent epidemic responses is not only evidence-based but also an equitable way forward for the current coronavirus disease (COVID-19) pandemic and future respiratory pandemics.

12 Jul 2021

Accelerating the design of minibinder therapeutics resilient to SARS-CoV-2 mutations

Multivalent protein-based minibinders hold great promise as potential prophylactic and treatment agents, as they can retain their activity against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern. This was revealed in a recent tour-de-force research study currently available on the bioRxiv* preprint server while the article undergoes the peer review process.

11 Jul 2021

Pfizer aims to implement boosters and a new vaccine based on SARS-CoV-2 Delta variant

The drugmaker Pfizer, one of the companies behind the Pfizer-BioNTech vaccine, or BNT162b2, awaits the green light to develop a COVID-19 booster shot that can protect against emerging variants. Pfizer’s COVID-19 vaccine has been shown to be 95% effective in an ongoing large-scale clinical trial against the original SARS-CoV-2 strain.

11 Jul 2021

Pfizer-BioNTech’s COVID-19 vaccine effective and safe for use among cancer patients

Researchers in Israel have conducted a study showing that the use of Pfizer-BioNTech’s coronavirus disease 2019 (COVID-19) vaccine appears to be safe and effective among patients with cancer.

11 Jul 2021

Respiratory News and Research

Study reports low risk for COVID-19 in Emergency Medical Service personnel exposed to aerosol-generating procedures

Patient characteristics including demographic factors and comorbidities can accurately predict the outcome of COVID-19 infection severity

Review details clinical signs of SARS-CoV-2 infection in domestic and wild cats

Natural compound 'pheophorbide a' demonstrates robust antiviral activity against SARS-CoV-2 in vitro

Real-world evidence SARS-CoV-2 mRNA vaccines work and help prevent worst outcomes

Study sheds light on immune processes involved in long COVID

Nose drops of modified 'friendly' bacteria offer protection against meningitis

New research examines the elimination of the B.1.362 + L452R variant in Israel

Millions of COVID-19 cases went undetected in the first six months of the pandemic, finds study

Chemicals found in common household products increase asthma risk

Review of scientific evidence supports zoonotic origin for SARS-CoV-2 with zero biological evidence for laboratory leak scenario

Scientists identify novel entry receptors for SARS-CoV-2

mRNA-based COVID-19 vaccine CV07050101 demonstrates limited immunogenicity in non-human primates

Composition and structure of nasopharyngeal microbiome relate to COVID-19 disease severity

What is behind the inconsistent results of COVID-19 clinical trials?

SARS-CoV-2 mRNA vaccine efficacy reduced in patients with CD20-B-cell depleting treatment history

Socioeconomic inequities and structural racism are neglected pieces of SARS-CoV-2 transmission networks

Accelerating the design of minibinder therapeutics resilient to SARS-CoV-2 mutations

Pfizer aims to implement boosters and a new vaccine based on SARS-CoV-2 Delta variant

Pfizer-BioNTech’s COVID-19 vaccine effective and safe for use among cancer patients

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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