Rheumatology News and Research

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Rheumatology is a sub-specialty in internal medicine and pediatrics, devoted to the diagnosis and therapy of rheumatic diseases. Rheumatologists mainly deal with clinical problems involving joints, soft tissues and allied conditions of connective tissues.

All patients with rheumatic disorders recommended to receive pneumococcal vaccine

Patients with rheumatoid arthritis, lupus, and other rheumatic conditions are more at risk for complications and death from pneumonia, meningitis, and other bacterial infections, yet most have not been vaccinated against infection.

29 Dec 2022

Study could pave the way for new drug to treat hand osteoarthritis

A new study, published in Science Translational Medicine by researchers at the University of Oxford has identified that Talarozole, a drug that is known to increase retinoic acid, was able to prevent osteoarthritis (OA) in disease models.

22 Dec 2022

Lupus Research Alliance announces recipients of the 2022 Distinguished Innovator Award focused on studying T cells in lupus

The Lupus Research Alliance (LRA) proudly announces the two outstanding recipients of the 2022 Distinguished Innovator Award (DIA): Hongbo Chi, PhD, and Joseph Craft, MD.

16 Dec 2022

Study finds a novel therapeutic target for prevention and treatment of gout

Many Americans think of gout as a disease from a bygone era, akin to rickets or scurvy. The condition commonly afflicted the rich and royal, including American historical figures such as Benjamin Franklin and Thomas Jefferson.

14 Dec 2022

Research extends the powerful tool of immunotherapy to autoimmune diseases

The cancer therapy known as CAR-T has revolutionized treatment of some blood cancers since it was introduced in 2017. The therapy uses genetically altered immune cells to home in on cancer cells and destroy them.

6 Dec 2022

Trial assesses the impact of two immunomodulators in reducing CV risk among rheumatoid arthritis patients

People with rheumatoid arthritis are at increased risk of cardiovascular (CV) disease, with studies indicating an approximate 50 percent increase in risk of CV events such as heart attack and stroke.

5 Dec 2022

Glycan signatures in rheumatic diseases and their associated functional implications

A new paper examines the understanding of glycosylation in an array of rheumatic diseases and indicates the potential for therapeutic interventions using the same mechanism.

28 Nov 2022

New mathematical model can predict SARS-CoV-2 incidence using wastewater-based epidemiology

Cetaqua and the BIOCOM-UPC research group develop a mathematical model to predict SARS-CoV-2 incidence in Catalonia using wastewater-based epidemiology.

24 Nov 2022

Study explores link between dynamic changes in metabolic syndrome and risk of gout

In a study published in Arthritis & Rheumatology that included nearly 1.3 million men aged 20–39 years who participated in three serial health check-ups at two-year intervals, men with metabolic syndrome (MetS) and those who developed MetS-;especially those with the MetS components of elevated triglycerides and abdominal obesity-;had higher risks of developing gout.

23 Nov 2022

New EULAR recommendations for screening and treating infections in AIIRD patients

It is already known that people who are immunocompromised are more prone to infections. Chronic and opportunistic infections are often found in people with an AIIRD, and may be linked to some of the immunosuppressive and immunomodulatory treatments used to treat these rheumatic diseases.

22 Nov 2022

Interdisciplinary guidelines for treatment of children with arthritis of the jaw

Interdisciplinary guidelines to optimize the treatment of childhood arthritis at global level. So far, there no uniform guidelines have existed for the treatment of arthritis of the jaw, a potentially debilitating consequence of juvenile arthritis.

20 Nov 2022

Researchers are developing calculator that weighs risk and benefit of taking osteoporosis drugs

Osteoporosis is a major, worsening public health problem and bisphosphonates which help restore a healthier balance of bone production and resorption, have been a relatively inexpensive, successful treatment, particularly for those at highest risk for fractures.

16 Nov 2022

PALS program effective in ensuring diverse representation in lupus clinical trials

The Lupus Research Alliance and its affiliate Lupus Therapeutics presented data at ACR Convergence 2022 with results showing the effectiveness of a pilot peer education program called the Patient Advocates for Lupus Studies (PALS), in increasing knowledge, perception, and willingness among people with Systemic Lupus Erythematosus (SLE) to participate in clinical trials.

14 Nov 2022

Mast cells in synovial tissue may explain why women report worse osteoarthritis pain than men

Investigators at Hospital for Special Surgery (HSS) have discovered that at the time of total knee replacement, women have significantly increased levels of immune cells called mast cells in synovial tissue surrounding the knee joint than men.

14 Nov 2022

Study assesses musculoskeletal health needs of underserved patients

To improve the health of a community, the first step is to identify its most pressing needs. To that end, in 2022 Hospital for Special Surgery (HSS) implemented a community-based participatory research (CBPR) approach to assess musculoskeletal health needs, identify health disparities and support the development of initiatives to address unmet needs.

14 Nov 2022

Study highlights the success of lupus peer support group that transitioned to virtual format during pandemic

A study at Hospital for Special Surgery highlights the success of a lupus peer support and education group that transitioned to a virtual format during the pandemic.

14 Nov 2022

Oral deucravacitinib shows promise in patients with active lupus

Tyrosine kinases are enzymes that play central roles in signaling by cytokines involved in the pathogenesis of autoimmune diseases, including lupus.

14 Nov 2022

First placebo-controlled long-term trial of anifrolumab shows positive results in patients with lupus

Type I interferon (IFN) is a powerful immune activator that is present at high levels in the majority of patients with lupus, an autoimmune disease. In Arthritis & Rheumatology, researchers report positive results from the first placebo-controlled long-term trial of anifrolumab-;a human monoclonal antibody that targets the type I IFN receptor-;in patients with lupus.

14 Nov 2022

Genicular nerve blocks provide short term pain relief for patients with knee osteoarthritis

Results from a recent clinical trial published by Wiley in Arthritis & Rheumatology demonstrate that patients with knee osteoarthritis experience short term pain relief from genicular nerve blocks-;or locally injected anesthetics that block nerves around the knee joint.

13 Nov 2022

Updated EULAR recommendations on the use of DMARDs for people with RA

Since their first publication in 2010, the EULAR recommendations for the use of disease-modifying anti-rheumatic treatments (DMARDs) in people with RA have become a most important publication in the field, and their updates are relied upon by many healthcare professionals, professional organizations and other stakeholders to offer an up-to-date and robust analysis on an optimal approach to the application of available treatment options in clinical practice.

11 Nov 2022

Rheumatology News and Research

Further Reading

All patients with rheumatic disorders recommended to receive pneumococcal vaccine

Study could pave the way for new drug to treat hand osteoarthritis

Lupus Research Alliance announces recipients of the 2022 Distinguished Innovator Award focused on studying T cells in lupus

Study finds a novel therapeutic target for prevention and treatment of gout

Research extends the powerful tool of immunotherapy to autoimmune diseases

Trial assesses the impact of two immunomodulators in reducing CV risk among rheumatoid arthritis patients

Glycan signatures in rheumatic diseases and their associated functional implications

New mathematical model can predict SARS-CoV-2 incidence using wastewater-based epidemiology

Study explores link between dynamic changes in metabolic syndrome and risk of gout

New EULAR recommendations for screening and treating infections in AIIRD patients

Interdisciplinary guidelines for treatment of children with arthritis of the jaw

Researchers are developing calculator that weighs risk and benefit of taking osteoporosis drugs

PALS program effective in ensuring diverse representation in lupus clinical trials

Mast cells in synovial tissue may explain why women report worse osteoarthritis pain than men

Study assesses musculoskeletal health needs of underserved patients

Study highlights the success of lupus peer support group that transitioned to virtual format during pandemic

Oral deucravacitinib shows promise in patients with active lupus

First placebo-controlled long-term trial of anifrolumab shows positive results in patients with lupus

Genicular nerve blocks provide short term pain relief for patients with knee osteoarthritis

Updated EULAR recommendations on the use of DMARDs for people with RA

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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