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Novel technology enhances potency and breadth of vaccine-induced responses through antigen presentation

Novel EABR technology enhances potency and breadth of vaccine-induced responses through antigen presentation.

30 May 2023

How do the outcomes of viral coinfections vary across host species?

In a recent study published in the journal PLOS Pathogens, researchers investigated the outcomes of coinfections of two viruses — Drosophila C Virus (DCV) and Cricket Paralysis Virus (CrPV) in 25 inbred lines of Drosophila melanogaster and 47 other host species belonging to the Drosophilidae family.

26 May 2023

New review unravels phthalates’ role in heart disease

Researchers review existing data on the impact of phthalate exposure on cardiovascular health.

25 May 2023

T-cell-inducing mRNA COVID-19 vaccine improves effectiveness

Researchers develop a lipid nanoparticle-formulated mRNA-based antigen encoding three SARS-CoV-2 peptides derived from non-structural proteins.

25 May 2023

COVID-19 'bites the apple': Abdominal obesity ignites cytokine storm

Abdominal obesity increases the risk of severe COVID-19 and mortality due to heightened inflammatory responses, according to a study on Japanese patients and a murine COVID-19 model. Blocking inflammatory cytokines and preventing obesity may improve survival rates.

24 May 2023

The adaptive immunity of human endemic viruses

Researchers studied the evolution of the ability of viruses to evade the neutralizing antibodies.

24 May 2023

Is COVID-19 booster vaccination in early pregnancy associated with an increased risk of spontaneous abortion?

Researchers studied the relationship between COVID-19 booster vaccination and spontaneous abortion.

24 May 2023

Surviving without glucose: uridine-derived ribose as an alternative energy source

Researchers attempted to identify new genes and molecular pathways that might supply energy when the availability of glucose or other nutrients is limited.

22 May 2023

Breast milk shields newborns: COVID-19 antibodies and microbiota from vaccinated mothers provide dual defense

Research paper discusses the differences in microbiota between high and low IgA subjects after the second dose of the COVID-19 vaccine. The study found that certain microbial features in breast milk can predict levels of anti-SARS-CoV-2 antibodies in breast milk one week post-second dose.

21 May 2023

Synthetic delivery vector STxB induces mucosal immunity against viral antigens

Research describes the development of a synthetic delivery vector called STxB for mucosal vaccination. It induces mucosal immunity, including resident memory CD8+ T cells and IgA antibodies, against antigens derived from mucosal viruses when administered intranasally in mice.

21 May 2023

COVID's latest twist: New XBB variant gains strength through recombination, outsmarting immunity and amplifying fusogenicity

Research discusses the emergence of a highly diversified SARS-CoV-2 Omicron subvariant called XBB, which is spreading rapidly around the world. XBB emerged through the recombination of two cocirculating BA.2 lineages, BJ.1 and BM.1.1.1, during the summer of 2022.

18 May 2023

Food preservative nisin: A gut game changer that safely alters microbiome composition

Nisin, a powerful bacteriocin, influences the gut microbiota and its functionality by modulating the abundance of specific bacterial groups and altering short-chain fatty acid synthesis.

18 May 2023

How the gut microbiome supports iron uptake by intestinal regulatory T-cells

Research paper discusses the relationship between iron deficiencies and immune tolerance in patients with inflammatory bowel disease. The study shows that high cellular iron levels fostered by pentanoate, a short-chain fatty acid produced by intestinal microbiota, are necessary for the homeostasis of regulatory T cells in the intestine, and iron deficiencies in Treg can result in lethal autoimmune disease.

17 May 2023

Democratizing RNA sequencing: A breakthrough in cost and efficiency

CSEM has supported the Lausanne-based start-up Alithea Genomics in developing a technology capable of processing hundreds of ribonucleic acid (RNA) samples in a single tube, which translates to a significant reduction in reagents and manual effort in the overall workflow.

From CSEM 17 May 2023

Researchers discover key epigenetic alteration associated with clinical course of liver cancer

Researchers at the Josep Carreras Leukaemia Research Institute, led by Dr. Manel Esteller, have discovered a key epigenetic alteration that anticipates the clinical course of liver cancer.

16 May 2023

Can beer intake improve heart health following oxidative injury?

Researchers examined the impact of antioxidants found in fermented beverages on tissue transcriptomics.

16 May 2023

The discovery of a novel orthonairovirus from Dermacentor silvarum ticks near the China–North Korea border

Researchers isolated a novel virus of the Orthonairovirus genus.

16 May 2023

Obesity undermines COVID-19 vaccines

Researchers examine the impact of obesity on COVID-19 outcomes and the effectiveness of vaccines in individuals with obesity. Using data from Scotland, the study explores the relationship between body mass index (BMI) and hospitalization/mortality due to COVID-19.

15 May 2023

Non-coding genetic molecules may hold promise for warning of esophageal cancer

Irregularities in the body's genetic coding to make proteins are linked to cancerous tumors. But most genetic material contains elements whose function isn't clear.

15 May 2023

Novel ingestible device enables non-invasive profiling of the gut microbiome, proteome, and metabolome

Researchers developed an ingestible device to collect samples from the human intestine.

12 May 2023

Ribonucleic Acid News and Research

Novel technology enhances potency and breadth of vaccine-induced responses through antigen presentation

How do the outcomes of viral coinfections vary across host species?

New review unravels phthalates’ role in heart disease

T-cell-inducing mRNA COVID-19 vaccine improves effectiveness

COVID-19 'bites the apple': Abdominal obesity ignites cytokine storm

The adaptive immunity of human endemic viruses

Is COVID-19 booster vaccination in early pregnancy associated with an increased risk of spontaneous abortion?

Surviving without glucose: uridine-derived ribose as an alternative energy source

Breast milk shields newborns: COVID-19 antibodies and microbiota from vaccinated mothers provide dual defense

Synthetic delivery vector STxB induces mucosal immunity against viral antigens

COVID's latest twist: New XBB variant gains strength through recombination, outsmarting immunity and amplifying fusogenicity

Food preservative nisin: A gut game changer that safely alters microbiome composition

How the gut microbiome supports iron uptake by intestinal regulatory T-cells

Democratizing RNA sequencing: A breakthrough in cost and efficiency

Researchers discover key epigenetic alteration associated with clinical course of liver cancer

Can beer intake improve heart health following oxidative injury?

The discovery of a novel orthonairovirus from Dermacentor silvarum ticks near the China–North Korea border

Obesity undermines COVID-19 vaccines

Non-coding genetic molecules may hold promise for warning of esophageal cancer

Novel ingestible device enables non-invasive profiling of the gut microbiome, proteome, and metabolome

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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