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Henry Ford Health cardiologists perform new coronary bypass procedure that replicates an old operation

Henry Ford Health Interventional cardiologists William O'Neill, M.D., and Khaldoon Alaswad, M.D., took a page out of the medical history books by performing a new coronary bypass procedure replicated from one not used in decades to treat a patient living with crippling angina - a severe symptom of coronary artery disease.

15 May 2023

Does birth setting impact birth outcome?

In the USA, the vast majority of mothers deliver in hospitals, with less than 2% giving birth in birth centers or at home. However, few systematic attempts have been made to understand how the latter trend impacts maternal health. A new research paper published in the American Journal of Obstetrics and Gynecology uses available data to conclude that hospital births provide better perinatal outcomes in all cases, with increased benefits in high-risk pregnancies.

14 May 2023

New study finds elevated inflammatory cytokines and lymphocytes linked to rare cases of myocarditis after COVID-19 vaccination

Researchers investigated a cohort of patients who developed myocarditis after SARS-CoV-2 mRNA vaccination.

10 May 2023

Researchers develop gene-edited stem cells to reduce arrhythmias in heart attack patients

In a recent study published in the journal Cell Stem Cell, researchers hypothesized that pacemaker-like activity of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) resulted in engraftment arrhythmias (EAs), which hampers the clinical use of cell-based therapy using hPSC-CMs for treatment of myocardial infarction (MI).

2 May 2023

Drugs targeting FXR1 may treat vascular proliferative diseases

Vascular diseases, including myocardial infarction, stroke, renal failure, and peripheral vascular disease, continue to account for one third of all mortality in the United States, Europe, and the developing world (World Health Organization, 2021).

2 May 2023

Understanding post-COVID interstitial lung disease: Causes, treatment options

After being hospitalized for three months with COVID-19 and double pneumonia in 2020, Houston police officer Hito Bazan awoke one morning to discover that he couldn't talk, eat, walk, or most importantly, breathe. Bazan was diagnosed with interstitial lung disease (ILD) known as pulmonary fibrosis (PF).

27 Apr 2023

As US life expectancy falls, experts cite the health impacts of incarceration

After spending 38 years in the Alabama prison system, one of the most violent and crowded in the nation, Larry Jordan felt lucky to live long enough to regain his freedom.

27 Apr 2023

Study reveals ERK signaling as a crucial molecular switch between scarring and regeneration

Why do some animals regenerate lost tissues after injury while others don't? Researchers from the lab of Kerstin Bartscherer (Osnabrück University and formerly Hubrecht Institute) and Ashley Seifert (University of Kentucky) studied spiny mice, which have a remarkable regenerative capacity, to answer this question.

26 Apr 2023

Novel cell signaling pathway could be targeted against aggressive pancreatic cancers

Researchers at the Johns Hopkins Kimmel Cancer Center identified a novel cell signaling pathway that potentially could be targeted in therapy for patients with aggressive pancreatic cancers.

24 Apr 2023

Mice study reveals a way to turn back the clock after heart attack

A recent study using mice has revealed a way to turn back the clock after heart attack. The researchers behind the work used RNAs to instruct cells in an injured heart to eliminate scar tissue and recreate cardiac muscle, allowing the heart to function like new again.

19 Apr 2023

People with Down syndrome are living longer, but the health system still treats many as kids

It took Samantha Lesmeister's family four months to find a medical professional who could see that she was struggling with something more than her Down syndrome.

17 Apr 2023

UW researchers engineer stem cells that do not generate dangerous arrhythmias

Researchers at the University of Washington School of Medicine in Seattle have engineered stem cells that do not generate dangerous arrhythmias, a complication that has to date thwarted efforts to develop stem-cell therapies for injured hearts.

7 Apr 2023

New treatment for fibrous dysplasia shows promising results in NIH clinical trial

A clinical trial at the National Institutes of Health found that a medication, denosumab, significantly reduced abnormal bone turnover in adults with fibrous dysplasia, a rare disease marked by weak and misshapen bones.

4 Apr 2023

NIH scientists discover an autoinflammatory disease caused by mutations in the LYN gene

Scientists have identified an autoinflammatory disease caused by mutations in the LYN gene, an important regulator of immune responses in health and disease.

28 Mar 2023

Psychological therapy can help provide better quality of life for women with endometriosis

Nearly 10% of Danish women suffer from endometriosis, which can cause serious pelvic pain.

23 Mar 2023

Researchers discover how a single mechanosensitive protein induces fibrosis

Researchers from Kyushu University have found how a single mechanosensitive protein induces the process that thickens and scars tissue, known as fibrosis. The protein, called VGLL3, was shown to contribute to fibrosis in multiple organs.

22 Mar 2023

Animal studies show potential of new drug to curb painful hyperinflammation from osteoarthritis

A team of researchers at the Keck School of Medicine of USC have found a drug with the potential for curbing painful hyperinflammation from osteoarthritis, according to results of an animal study.

22 Mar 2023

All-female gynecologic oncology team treating women at Hackensack University Medical Center

When Linda Muller was diagnosed with serous cell endometrial cancer in 2016, she and her husband George turned to the all-female gynecologic oncology team at John Theurer Cancer Center at Hackensack University Medical Center for her care -; a decision that the couple credits with Linda's complete recovery and continued good health seven years later.

16 Mar 2023

New biomimetic model helps study wound healing in burn and laceration wounds

Burn wounds are notoriously prone to bacterial infection and typically lead to a larger amount of scar tissue than laceration wounds.

15 Mar 2023

New project to validate a novel hydrogel for preventing scar tissue formation after heart attack

The European Union has awarded a European Consortium €4.5 million for the ELR-Scar project to validate a novel hydrogel biomaterial that will prevent scar tissue from forming in the heart following a heart attack.

10 Mar 2023