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Sartorius releases the 6th edition of its popular live-cell analysis handbook

Sartorius, a leader in new technologies for real-time, live-cell imaging and analysis, has released the 6th edition of its popular Live-Cell Analysis Handbook.

From Sartorius 10 Oct 2022

Silver nanoparticle and polyurethane composite provides potential coating options to limit fomite transmission of SARS-CoV-2

In a new study, researchers synthesized and evaluated a silver and polyurethane nanocomposite surface coating material that exhibits antiviral activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

7 Oct 2022

Neonatal mice-based model established that allows for the transmission of clinical SARS-CoV-2 isolates

Researchers established a neonatal mice model that enabled SARS-CoV-2 transmission.

7 Oct 2022

Mouthwashes inhibit the infectivity of SARS-CoV-2 variants

SARS-CoV-2, the virus that causes COVID-19, is an airborne disease transmitted via aerosols, which are spread from the oral and nasal cavities-;the mouth and the nose.

6 Oct 2022

Yeast display used to generate SARS-CoV-2 RBD-specific nanobodies

Researchers engineered biparatopic nanobodies against SARS-CoV-2.

5 Oct 2022

Structural analysis of monkeypox virus H1 dual phosphatase as a pan-poxvirus target

In a new study, researchers determined the 1.8-Å resolution crystal structure of the H1 dual specific phosphatase (DSP) of monkeypox virus (MPXV) that is crucial for viral replication, making it an attractive antiviral target.

5 Oct 2022

How COVID-19 affects the female reproductive system

A new review in the Biology of Reproduction journal analyzed the relationship between the immune system and the female reproductive system while focusing on the effects of COVID-19-associated immune responses on the reproductive system. The study searched PubMed to identify peer-reviewed literature in English up to May 2022 and finally included 83 studies.

3 Oct 2022

Broadly neutralizing antibodies are the blueprint for variant-proof, pansarbecovirus vaccines

A recent Nature Reviews Immunology study has summarized the efficacy of neutralizing antibodies that target four main regions of the spike (S) protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), namely, the receptor-binding domain (RBD) in the S1 subunit, the fusion peptide region in the S2 subunit, the stem helix region, and the N-terminal domain.

2 Oct 2022

Duration of infectiousness, predictors of ongoing individual infectiousness, and diagnostic tests for acute SARS-CoV-2 infection

Researchers explored SARS-CoV-2 variants of concern/interest (VOC/VOI) kinetics and variations among non-hospitalized acute COVID-19 patients.

29 Sep 2022

Can the gut be an alternative route for SARS-CoV-2 entry?

Researchers reviewed the gut pathophysiology of SARS-CoV-2 infection.

28 Sep 2022

Association of self-reported chronic fatigue and retinal microcirculation in post-COVID-19 syndrome patients

Researchers investigated the potential association between self-reported chronic fatigue and retinal microcirculation among post-COVID-19 syndrome patients.

27 Sep 2022

Rational treatment strategies for SARS-CoV-2 derived from human pluripotent stem cells models

In a recent study posted to the bioRxiv* preprint server, researchers in Australia explored the molecular mechanisms of the pulmonary and cardiac complications caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection using human stem-cell-derived cardiac and lung cells.

27 Sep 2022

Researchers uncover a new way the immune system detects coronavirus infection

In a recent study posted to bioRxiv*, researchers in the United States demonstrated that the main protease (Mpro) of coronaviruses (CoVs) activates host inflammasome responses.

27 Sep 2022

LncDACH1 may be a potential therapeutic target for pulmonary fibrosis

This new article publication from Acta Pharmaceutica Sinica B, discusses how LncRNA DACH1 protects against pulmonary fibrosis by binding to SRSF1 to suppress CTNNB1 accumulation.

26 Sep 2022

All SARS-CoV-2 variants blocked by a simple peptide with nanomolar neutralizing efficacy

In a recent study published in the journal PNAS, researchers from Finland and the United States reported a novel heptad repeat 2 (HR2) peptide that inhibited severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) without any chemical modifications.

21 Sep 2022

Study finds telomeres can set damage thresholds for cancer cells above which they cannot continue to divide

A recent study hypothesized that ALT might compromise telomere integrity if not restricted appropriately.

21 Sep 2022

O-linked sialoglycans affect SARS-CoV-2 spike cleavage

In a recent study posted to the bioRxiv* preprint server, researchers from Spain, the United Kingdom, and the United States used chemical tools to uncover the molecular details of glycan-mediated modulation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) processing.

19 Sep 2022

Study reveals pan-antiviral properties of PDC-109 bovine seminal plasma protein

In a new study, researchers explored the antiviral activity of the bovine seminal plasma protein PDC-109 against various mammalian viruses, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

15 Sep 2022

Research shows a complex relationship between vaping and SARS-CoV-2 infection

In a recent study posted to the bioRxiv* pre-print server, researchers at the University of California, Riverside investigated the effects of electronic cigarette (EC) use as a risk factor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

14 Sep 2022

Small molecule inhibitor found to be effective against SARS-CoV-2 variants

In a new study, researchers developed RK-33, a small molecule inhibitor of DDX3, and evaluated its efficacy against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs).

12 Sep 2022

Serine News and Research

Sartorius releases the 6th edition of its popular live-cell analysis handbook

Silver nanoparticle and polyurethane composite provides potential coating options to limit fomite transmission of SARS-CoV-2

Neonatal mice-based model established that allows for the transmission of clinical SARS-CoV-2 isolates

Mouthwashes inhibit the infectivity of SARS-CoV-2 variants

Yeast display used to generate SARS-CoV-2 RBD-specific nanobodies

Structural analysis of monkeypox virus H1 dual phosphatase as a pan-poxvirus target

How COVID-19 affects the female reproductive system

Broadly neutralizing antibodies are the blueprint for variant-proof, pansarbecovirus vaccines

Duration of infectiousness, predictors of ongoing individual infectiousness, and diagnostic tests for acute SARS-CoV-2 infection

Can the gut be an alternative route for SARS-CoV-2 entry?

Association of self-reported chronic fatigue and retinal microcirculation in post-COVID-19 syndrome patients

Rational treatment strategies for SARS-CoV-2 derived from human pluripotent stem cells models

Researchers uncover a new way the immune system detects coronavirus infection

LncDACH1 may be a potential therapeutic target for pulmonary fibrosis

All SARS-CoV-2 variants blocked by a simple peptide with nanomolar neutralizing efficacy

Study finds telomeres can set damage thresholds for cancer cells above which they cannot continue to divide

O-linked sialoglycans affect SARS-CoV-2 spike cleavage

Study reveals pan-antiviral properties of PDC-109 bovine seminal plasma protein

Research shows a complex relationship between vaping and SARS-CoV-2 infection

Small molecule inhibitor found to be effective against SARS-CoV-2 variants

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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