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The importance of using the American Heart Association-recommended technique for blood pressure measurement

A modified cross-over design to compare methods of taking blood pressure readings.

19 Sep 2023

Ohio State University launches first-in-world clinical trial of heart failure device

The Ohio State University Wexner Medical Center on Wednesday randomized the first patient in the world in a clinical trial evaluating the effectiveness of a device designed to alleviate heart failure symptoms.

4 Sep 2023

$11.7M from Department of Defense to fund research on discovering a treatment for hydrocephalus

Researchers at the School of Science at IUPUI will lead two grants totaling $11.7 million from the U.S. Department of Defense to fund research on discovering a drug treatment for hydrocephalus, a condition commonly associated with complications from traumatic brain injury that causes cerebrospinal fluid to accumulate in the brain.

15 Jun 2023

Novel molecular mechanism responsible for common form of acquired hydrocephalus discovered

Mass General researchers have discovered a novel molecular mechanism responsible for the most common forms of acquired hydrocephalus, potentially opening the door to the first-ever nonsurgical treatment for a life-threatening disease that affects about a million Americans.

8 Mar 2023

Review: Latest findings in the spina bifida-related care of many comorbidities

Open spina bifida (SB), a neural tube defect (NTD), also known as myelomeningocele, remains the most complex congenital abnormality of the central nervous system compatible with long term survival.

21 Feb 2023

FUSCLEAN technology enables preventive cleaning of catheters and valves in patients with hydrocephaly

Researchers at the University of Seville and University Hospital Virgen del Rocío have published the results of the first successful test of a new technology created to prevent obstructions in catheters and valves (shunts) implanted in the brain of patients with hydrocephalus.

12 Oct 2022

Consumption of highly refined fiber may increase liver cancer risk in some people

Many people commonly consume fiber-enriched foods to promote weight loss and prevent chronic diseases such as diabetes and cancer.

26 Sep 2022

Researchers implement standardized shunt infection prevention bundle within the adult population

Researchers at the University of Calgary, Alberta, Canada, investigated theimplementation of a standardized shunt infection prevention bundle, a set of evidence-based practices termed the Calgary Adult Shunt Infection Prevention Protocol (CASIPP) to prevent ventriculoperitoneal (VP) shunt infections within an adult hydrocephalus patient population. The initial implementation of the CASIPP resulted in infection reduction, and then the rate of infections was dramatically reduced after the preoperative skin antiseptic was replaced with 2% chlorhexidine gluconate in 70% isopropyl alcohol.

3 Aug 2022

Multi-center trial shows promising results for implant-free interatrial shunt device to treat heart failure patients

Results from early clinical evaluation of the Alleviant System to treat heart failure patients with preserved and reduced ejection fraction (HFpEF and HFrEF) was presented today as late-breaking clinical research at the Society for Cardiovascular Angiography & Interventions (SCAI) 2022 Scientific Sessions.

20 May 2022

Patients with COVID-19 pneumonitis and moderate to severe ARDS treated with sildenafil

A new study published in the British Journal of Anaesthesia aimed to determine whether sildenafil could improve gaseous exchange in patients with COVID-19 ARDS with pulmonary hypertension, RV dysfunction, or both.

17 May 2022

Study shows safety, feasibility of intranasal milk therapy for infants with intraventricular hemorrhage

A new study demonstrates that intranasal human milk is a safe and feasible intervention for intraventricular hemorrhage, a serious cause of morbidity in preterm infants.

22 Apr 2022

Better understanding of hydrocephalus could lead to improved treatments

Hydrocephalus, or "water on the brain," occurs when the cerebral ventricles-; four interconnected cavities of the brain that are filled with cerebrospinal fluid-; become enlarged, but its cause is unknown in many cases.

18 Apr 2022

Researchers aim to study the underlying pathophysiology of diastolic heart failure

Of the estimated five million patients in the U.S. diagnosed with heart failure annually, nearly half will have heart failure with preserved ejection fraction (HFpEF). Also known as diastolic heart failure, HFpEF occurs when the heart's lower left chamber loses its ability to relax and fill up with enough blood in between in each heartbeat.

23 Mar 2022

Patients undergoing neurosurgical operations with concomitant COVID-19 infection have higher rates of perioperative complications

This unique paper compares neurosurgical patients with COVID-19 for perioperative complications to those without COVID-19.

31 Jan 2022

Model simulations show no need for DEX dose adjustments in COVID-19 patients with liver disease

A recent study sed PBPK modeling to demonstrate the use of DEX PKs for the treatment of COVID-19 in patients with liver impairment.

17 Nov 2021

World-renowned expert to lead pediatric cardiology division at Washington University School of Medicine

Andrew C. Glatz, MD, an internationally recognized expert in pediatric interventional cardiology, has been selected to lead the Division of Pediatric Cardiology in the Department of Pediatrics at Washington University School of Medicine in St. Louis.

30 Oct 2021

Researchers receive $14 million grant to study the effectiveness of hydrocephalus treatment

Patients diagnosed with idiopathic normal pressure hydrocephalus (iNPH), a type of brain swelling most commonly seen in older adults — and for which the underlying cause is unknown — are typically treated by surgically installing a shunt (drain) to remove the excess fluid associated with the condition.

26 Aug 2021

Deletion of an embryonic gene in liver cells completely wipes out bile ducts of newborn mice

Scientists from the University of Pittsburgh School of Medicine described a new phenomenon in which the deletion of a single gene involved in liver embryogenesis completely wipes out bile ducts of newborn mice.

6 Jul 2021

Atrial fenestration during atrioventricular septal defect repair is linked to higher mortality rate

A new study, presented today at the AATS 101st Annual Meeting, shows an association between decreased survival at five years and leaving an atrial communication at biventricular repair of unbalanced AVSD after adjusting for other known risk factors.

3 May 2021

FDA permits marketing of new device to protect athletes from harmful effects of head impacts

Today, the U.S. Food and Drug Administration authorized marketing of a new device intended to be worn around the neck of athletes aged 13 years and older during sports activities to aid in the protection of the brain from the effects associated with repetitive sub-concussive head impacts.

26 Feb 2021