Smallpox News and Research

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Smallpox is a highly contagious disease caused by the variola virus, a member of the Orthopox virus family. It is one of the most devastating diseases known to humanity, with a mortality rate as high as 30%. In 1967, the World Health Organization embarked upon an intensified vaccination campaign to eliminate smallpox, which culminated in the successful eradication of the disease globally by 1980.

By the mid-1980s, there were only two known repositories of variola virus: the Institute of Virus Preparations in Russia, and the US CDC. The events in the US in September and October 2001 highlighted the risk that the variola virus might be used as an agent of bioterrorism. Governments around the world are taking precautionary measures to be ready to deal with a potential smallpox outbreak.
Study highlights the efficacy of MVA-BN booster vaccination in inducing durable B cell memory responses against monkeypox

Study highlights the efficacy of MVA-BN booster vaccination in inducing durable B cell memory responses against monkeypox

The kinetics of T cell response, the inflammatory profile, and the pox-specific T cell induction in monkeypox infection

The kinetics of T cell response, the inflammatory profile, and the pox-specific T cell induction in monkeypox infection

Transmission of monkeypox virus atypical and unique in 2022

Transmission of monkeypox virus atypical and unique in 2022

What is the effectiveness of tecovirimat for treatment of monkeypox?

What is the effectiveness of tecovirimat for treatment of monkeypox?

The maternal and perinatal outcomes of pregnancies complicated by monkeypox infection

The maternal and perinatal outcomes of pregnancies complicated by monkeypox infection

False positive monkeypox tests in low-risk patients with no exposures

False positive monkeypox tests in low-risk patients with no exposures

Are antibodies induced by historic smallpox vaccination cross-reactive with the monkeypox virus?

Are antibodies induced by historic smallpox vaccination cross-reactive with the monkeypox virus?

CDC report shows people with monkeypox have higher than expected rates of HIV and STIs

CDC report shows people with monkeypox have higher than expected rates of HIV and STIs

Monkeypox in the WHO European region: epidemiological features, disease severity, and the impact of smallpox vaccination

Monkeypox in the WHO European region: epidemiological features, disease severity, and the impact of smallpox vaccination

Dissecting vaccinia virus and monkeypox virus-specific T cell responses in humans

Dissecting vaccinia virus and monkeypox virus-specific T cell responses in humans

The prevalence and spectrum of neurological and psychiatric presentations of human monkeypox infection

The prevalence and spectrum of neurological and psychiatric presentations of human monkeypox infection

A new monkeypox vaccine is needed to prevent global transmission

A new monkeypox vaccine is needed to prevent global transmission

ACTG announces the initiation of trial evaluating the safety and efficacy of monkeypox treatment

ACTG announces the initiation of trial evaluating the safety and efficacy of monkeypox treatment

Phase 3 clinical trial commences to evaluate antiviral for monkeypox

Phase 3 clinical trial commences to evaluate antiviral for monkeypox

Clinical trial begins evaluating alternative strategies to administer the JYNNEOS monkeypox vaccine

Clinical trial begins evaluating alternative strategies to administer the JYNNEOS monkeypox vaccine

Researchers review the epidemiology, clinical character, treatment, and prevention of human monkeypox

Researchers review the epidemiology, clinical character, treatment, and prevention of human monkeypox

Study indicates that HIV-infected and uninfected patients have similar monkeypox illness outcomes

Study indicates that HIV-infected and uninfected patients have similar monkeypox illness outcomes

The virology, epidemiology, transmission, clinical manifestations, diagnosis, management, and prevention strategies associated with monkeypox

The virology, epidemiology, transmission, clinical manifestations, diagnosis, management, and prevention strategies associated with monkeypox

The existing molecular variance levels in haplotypes of the interferon-alpha-beta receptor gene in Orthopoxviruses

The existing molecular variance levels in haplotypes of the interferon-alpha-beta receptor gene in Orthopoxviruses

Neurological manifestations associated with monkeypox infection

Neurological manifestations associated with monkeypox infection

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