Smallpox News and Research

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Smallpox is a highly contagious disease caused by the variola virus, a member of the Orthopox virus family. It is one of the most devastating diseases known to humanity, with a mortality rate as high as 30%. In 1967, the World Health Organization embarked upon an intensified vaccination campaign to eliminate smallpox, which culminated in the successful eradication of the disease globally by 1980.

By the mid-1980s, there were only two known repositories of variola virus: the Institute of Virus Preparations in Russia, and the US CDC. The events in the US in September and October 2001 highlighted the risk that the variola virus might be used as an agent of bioterrorism. Governments around the world are taking precautionary measures to be ready to deal with a potential smallpox outbreak.

Further Reading

False positive monkeypox tests in low-risk patients with no exposures

False positive monkeypox tests in low-risk patients with no exposures

13 Sep 2022
Are antibodies induced by historic smallpox vaccination cross-reactive with the monkeypox virus?

Are antibodies induced by historic smallpox vaccination cross-reactive with the monkeypox virus?

12 Sep 2022
CDC report shows people with monkeypox have higher than expected rates of HIV and STIs

CDC report shows people with monkeypox have higher than expected rates of HIV and STIs

12 Sep 2022
Monkeypox in the WHO European region: epidemiological features, disease severity, and the impact of smallpox vaccination

Monkeypox in the WHO European region: epidemiological features, disease severity, and the impact of smallpox vaccination

12 Sep 2022
Dissecting vaccinia virus and monkeypox virus-specific T cell responses in humans

Dissecting vaccinia virus and monkeypox virus-specific T cell responses in humans

12 Sep 2022
The prevalence and spectrum of neurological and psychiatric presentations of human monkeypox infection

The prevalence and spectrum of neurological and psychiatric presentations of human monkeypox infection

12 Sep 2022
A new monkeypox vaccine is needed to prevent global transmission

A new monkeypox vaccine is needed to prevent global transmission

11 Sep 2022
ACTG announces the initiation of trial evaluating the safety and efficacy of monkeypox treatment

ACTG announces the initiation of trial evaluating the safety and efficacy of monkeypox treatment

9 Sep 2022
Phase 3 clinical trial commences to evaluate antiviral for monkeypox

Phase 3 clinical trial commences to evaluate antiviral for monkeypox

9 Sep 2022
Clinical trial begins evaluating alternative strategies to administer the JYNNEOS monkeypox vaccine

Clinical trial begins evaluating alternative strategies to administer the JYNNEOS monkeypox vaccine

8 Sep 2022
Researchers review the epidemiology, clinical character, treatment, and prevention of human monkeypox

Researchers review the epidemiology, clinical character, treatment, and prevention of human monkeypox

8 Sep 2022
Study indicates that HIV-infected and uninfected patients have similar monkeypox illness outcomes

Study indicates that HIV-infected and uninfected patients have similar monkeypox illness outcomes

7 Sep 2022
The virology, epidemiology, transmission, clinical manifestations, diagnosis, management, and prevention strategies associated with monkeypox

The virology, epidemiology, transmission, clinical manifestations, diagnosis, management, and prevention strategies associated with monkeypox

6 Sep 2022
The existing molecular variance levels in haplotypes of the interferon-alpha-beta receptor gene in Orthopoxviruses

The existing molecular variance levels in haplotypes of the interferon-alpha-beta receptor gene in Orthopoxviruses

6 Sep 2022
Neurological manifestations associated with monkeypox infection

Neurological manifestations associated with monkeypox infection

5 Sep 2022
Impact of vaccinia virus-based vaccines on the 2022 monkeypox virus outbreak

Impact of vaccinia virus-based vaccines on the 2022 monkeypox virus outbreak

5 Sep 2022
Monkeypox infection causing acute myocarditis - case report

Monkeypox infection causing acute myocarditis - case report

5 Sep 2022
Case study shows potential to develop myocarditis following monkeypox infection

Case study shows potential to develop myocarditis following monkeypox infection

2 Sep 2022
Researchers study the long-term consequences of Finland’s first vaccine mandate against smallpox

Researchers study the long-term consequences of Finland’s first vaccine mandate against smallpox

2 Sep 2022
Globalization and cessation of smallpox vaccination are influencing monkeypox spread

Globalization and cessation of smallpox vaccination are influencing monkeypox spread

1 Sep 2022

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