Somatostatin News and Research

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Inhibitory interneurons play a crucial role in fear memory expression and recall

Memory, a fundamental tool for our survival, is closely linked with how we encode, recall, and respond to external stimuli.

8 Nov 2023

Hormones and high blood pressure: Study reveals endocrine culprits and targeted treatments

Researchers delve into endocrine causes of hypertension (HTN), revealing key culprits like primary aldosteronism and Cushing's syndrome. The study also evaluates the efficacy of various treatments, offering valuable insights for tackling this widespread health issue.

15 Oct 2023

Loss of brain interneurons linked to cognitive deficits in aging

Normal aging is usually associated with a decline in memory, although it is unclear what factors play a role.

28 Sep 2023

Binge drinking during adolescence leads to long-lasting brain changes, research suggests

Heavy alcohol consumption may cause permanent dysregulation of neurons, or brain cells, in adolescents, according to a new study in mice.

9 Jun 2023

Targeting stem cells from the human stomach for treating diabetes

Stem cells from the human stomach can be converted into cells that secrete insulin in response to rising blood sugar levels, offering a promising approach to treating diabetes, according to a preclinical study from researchers at Weill Cornell Medicine.

25 May 2023

Study opens new possibilities of tailoring radiopharmaceutical treatment to neuroendocrine cancer patients

A simple blood draw can provide physicians with valuable information that can determine if peptide receptor radionuclide therapy (PRRT) is likely to be effective in a patient with neuroendocrine cancer.

7 Apr 2023

New strategies to beat rare tumors of the adrenal gland

Only one in 100,000 people suffer from a pheochromocytoma, a tumor of the adrenal gland. If the tumor has already metastasized, a radioactive compound can be used to detect malignant cells that have spread to other parts of the body, and to irradiate them from the inside.

9 Feb 2023

Study provides insight into how sleep and wakefulness regulate inhibitory synapses

Using a mouse model, researchers have discovered a new daily rhythm in a type of synapse that dampens brain activity.

1 Nov 2022

Brain changes can be studied in very early stages of neurodegenerative diseases

Many changes take place in the brain long before symptoms appear. This has been shown in mice in two studies of prion diseases in which the brain gradually deteriorates.

10 Oct 2022

uPAR may be a promising target for therapy in patients with neuroendocrine neoplasms

A novel PET radiotracer can accurately assess the presence of a biomarker that indicates the level of tumor aggressiveness in neuroendocrine neoplasms (NENs).

28 Sep 2022

Study reveals cellular underpinnings of motor memory acquisition and consolidation

When you are first learning how to ride a bicycle or play a musical instrument, your physical movements are uncoordinated at best.

14 Sep 2022

How a key brain network responds to seasonal shifts in day length

A recent paper examined the difference in neuronal communication in the hypothalamic network that regulates physiological function in response to the photoperiod.

8 Sep 2022

Somatostatin neurons' properties are specialized in different subregions of the cortex, finds study

The brain's cerebral cortex is made up of distinct regions involved in myriad processes, from sensory perception to cognitive functions like memory, attention, and decision-making. University of Pittsburgh neuroscience researchers have found that the properties of one neuron subtype-;somatostatin neurons-;are specialized in different subregions of the cortex.

6 Sep 2022

Researchers evaluate the brain circuits involved in social defeat stress-induced sleep in mice

The stress surrounding being defeated by another mouse activates mouse midbrain cells, promoting sleep and reducing anxiety, according to a new study.

30 Jun 2022

Deep-water cone snails produce a potentially painkilling compound, study reports

Scientists already know that the venom of cone snails, which prowl the ocean floor for a fish dinner, contains compounds that can be adapted as pharmaceuticals to treat chronic pain, diabetes and other human maladies.

24 Mar 2022

Mini-stomach organoids could be used to study how SARS-CoV-2 infection affects children

The team, led from Great Ormond Street Hospital (GOSH), UCL Great Ormond Street Institute of Child Health (UCL GOS ICH) and the Istituto Zooprofilattico Sperimentale delle Venezie (Legnaro, Italy), have built on recent advances to grow 'mini-organs' in a laboratory, known as organoids.

2 Dec 2021

Somatostatin News and Research

Inhibitory interneurons play a crucial role in fear memory expression and recall

Hormones and high blood pressure: Study reveals endocrine culprits and targeted treatments

Loss of brain interneurons linked to cognitive deficits in aging

Binge drinking during adolescence leads to long-lasting brain changes, research suggests

Targeting stem cells from the human stomach for treating diabetes

Study opens new possibilities of tailoring radiopharmaceutical treatment to neuroendocrine cancer patients

New strategies to beat rare tumors of the adrenal gland

Study provides insight into how sleep and wakefulness regulate inhibitory synapses

Brain changes can be studied in very early stages of neurodegenerative diseases

uPAR may be a promising target for therapy in patients with neuroendocrine neoplasms

Study reveals cellular underpinnings of motor memory acquisition and consolidation

How a key brain network responds to seasonal shifts in day length

Somatostatin neurons' properties are specialized in different subregions of the cortex, finds study

Researchers evaluate the brain circuits involved in social defeat stress-induced sleep in mice

Deep-water cone snails produce a potentially painkilling compound, study reports

Mini-stomach organoids could be used to study how SARS-CoV-2 infection affects children

Study proves safety and effectiveness of novel radionuclide therapy for neuroendocrine neoplasms

UVA researchers identify an unknown trigger for epilepsy seizures

Scientists find clues to how a specific synapse type regulates anxiety-like behavior

PRRT technology may offer new treatment approaches for neuroendocrine tumors

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