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BNT162b2 booster vaccination induces robust humoral and cellular immune responses

Scientists evaluate the humoral and cellular immune responses in individuals who have received a third booster dose of mRNA-based COVID-19 vaccine.

17 Mar 2022

Mortality among hospitalized Iranian COVID-19 patients during Alpha and Delta waves

Scientists analyze the death proportion and risk of death among COVID-19 hospitalized patients over time and during different waves of the pandemic.

17 Mar 2022

Novel screening method detects new N501T SARS-CoV-2 variant

Researchers develop two SARS-CoV-2 Mutation Discrimination assays that have been designed to detect 501 and 484 mutations on the spike protein.

17 Mar 2022

Excessive neuropeptide secretion in the lungs can lead to fluid buildup and poor oxygenation

COVID-19 has put a spotlight on the pulmonary and nervous systems, but there is still much to learn about how they interact. Researchers at University of California San Diego School of Medicine recently explored this relationship in the context of a childhood lung disease, but their findings may also apply to COVID-19 symptoms.

17 Mar 2022

Hispanic/Latino youth with food insecurity have worse cardiometabolic profiles, study shows

Hispanic/Latino youths with limited access to nutritionally adequate food – and especially those whose parents were foreign-born -- had worse cardiometabolic profiles than their "food secure" counterparts, according to a study published in Pediatrics.

17 Mar 2022

Omicron SARS-CoV-2 variant is more stable than its ancestral strain on smooth and porous surfaces

Researchers showed that the SARS-CoV-2 Omicron variant of concern is more stable on smooth and porous surfaces compared to its five ancestral strains.

17 Mar 2022

Evaluating vesicular stomatitis virus-based COVID-19 vaccines against SARS-CoV-2 variants in hamsters

Researchers assessed the efficacy of vesicular stomatitis virus-based coronavirus disease 2019 vaccines in Syrian golden hamsters.

17 Mar 2022

Study reports thiopurines inhibit the replication of the betacoronaviruses HCoV-OC43 and SARS-CoV-2

Researchers demonstrated that the thiopurines block coronaviruses spike protein assembly and integration into progeny virions.

17 Mar 2022

Narrative review reports two important mediators in SARS-CoV-2-induced ischemic stroke recovery

Researchers explored neuroinflammation and COVID-19-induced ischemic stroke recovery.

17 Mar 2022

Study finds co-infected individuals carrying two distinct lineages of SARS-CoV-2 in Argentina

Researchers used molecular surveillance to identify cases of co-infection with SARS-CoV-2 variants of concern Delta and Omicron reported in Argentina during December 2021 and January 2022.

17 Mar 2022

Study reports reduced disease severity in Syrian hamsters during re-infection with SARS-CoV-2 Delta variant

Researchers studied the immune responses in Syrian hamsters re-infected with SARS-CoV-2 Delta and B.1 variants three months after the primary infection.

17 Mar 2022

Researchers evaluate predictors for mortality in hospitalized COVID-19 patients

Researchers identified independent factors associated with early and late deaths in hospitalized COVID-19 patients.

17 Mar 2022

Biomarkers to identify SARS-CoV-2 patients requiring invasive mechanical ventilation

Researchers evaluated biomarkers that could help identify COVID-19 patients needing invasive mechanical ventilation.

17 Mar 2022

Novel mathematical model could predict the evolutionary trend of SARS-CoV-2

Researchers used a novel mathematical model to simulate SARS-CoV-2 dynamics inside the host.

17 Mar 2022

Novel fusion inhibitor blocks SARS-CoV-2 spike-mediated cell-cell fusion

Researchers constructed a novel fusion inhibitor−based recombinant protein, referred to as 5−Helix, to block SARS-CoV-2 spike-mediated cell-cell fusion.

17 Mar 2022

Impact of B-cell depletion therapy on hospitalized COVID-19 patients

Researchers assessed the clinical outcomes in patients hospitalized with SARS-CoV-2 infections who were previously treated with B-cell depletion therapy.

17 Mar 2022

Study finds serum antibody levels after BNT162b2 booster dropped significantly but remained higher than after the second dose

A recent study assessed the reduction in antibody titers observed after the third dose of SARS-CoV-2 BNT162b2 vaccine in adults.

17 Mar 2022

The immunogenicity of homologous and heterologous boosters in adults who received inactivated COVID-19 vaccine six months prior

Researchers compared the efficacy of booster doses of heterologous intramuscular and aerosolized adenovirus-vectored vaccine, a recombinant protein-based ZF2001 vaccine, and homologous CoronaVac vaccines.

17 Mar 2022

Study suggests single nucleotide polymorphism in interferon receptor impacts COVID-19 outcomes

Researchers reported the association of a single nucleotide polymorphism rs9984273 in the interferon-alpha/beta receptor gene with outcomes of acute respiratory distress syndrome and COVID-19.

17 Mar 2022

Researchers develop extraction-free saliva RT-LAMP assay for workplace surveillance of SARS-CoV-2

Researchers developed a saliva-based, extraction-free reverse transcription loop-mediated isothermal amplification workflow for SARS-CoV-2 detection.

17 Mar 2022

Syndrome News and Research

BNT162b2 booster vaccination induces robust humoral and cellular immune responses

Mortality among hospitalized Iranian COVID-19 patients during Alpha and Delta waves

Novel screening method detects new N501T SARS-CoV-2 variant

Excessive neuropeptide secretion in the lungs can lead to fluid buildup and poor oxygenation

Hispanic/Latino youth with food insecurity have worse cardiometabolic profiles, study shows

Omicron SARS-CoV-2 variant is more stable than its ancestral strain on smooth and porous surfaces

Evaluating vesicular stomatitis virus-based COVID-19 vaccines against SARS-CoV-2 variants in hamsters

Study reports thiopurines inhibit the replication of the betacoronaviruses HCoV-OC43 and SARS-CoV-2

Narrative review reports two important mediators in SARS-CoV-2-induced ischemic stroke recovery

Study finds co-infected individuals carrying two distinct lineages of SARS-CoV-2 in Argentina

Study reports reduced disease severity in Syrian hamsters during re-infection with SARS-CoV-2 Delta variant

Researchers evaluate predictors for mortality in hospitalized COVID-19 patients

Biomarkers to identify SARS-CoV-2 patients requiring invasive mechanical ventilation

Novel mathematical model could predict the evolutionary trend of SARS-CoV-2

Novel fusion inhibitor blocks SARS-CoV-2 spike-mediated cell-cell fusion

Impact of B-cell depletion therapy on hospitalized COVID-19 patients

Study finds serum antibody levels after BNT162b2 booster dropped significantly but remained higher than after the second dose

The immunogenicity of homologous and heterologous boosters in adults who received inactivated COVID-19 vaccine six months prior

Study suggests single nucleotide polymorphism in interferon receptor impacts COVID-19 outcomes

Researchers develop extraction-free saliva RT-LAMP assay for workplace surveillance of SARS-CoV-2

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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