Therapeutics News and Research

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Bretylium tosylate has unique benefits for patients with acute myocardial infarction

An "old" drug has unique benefits for patients with acute myocardial infarction (AMI; commonly known as heart attack), a finding that may contribute to a new understanding of how heart attacks develop, according to an article in the September/October American Journal of Therapeutics.

10 Nov 2004

New studies demonstrate efficacy of novel Lipoxin analog in laboratory models of Crohn's disease

Berlex announced today that new laboratory results demonstrate that its modified version of the naturally occurring lipoxin molecule exerts potent anti-inflammatory and immunomodulatory effects in Crohn's disease in vivo models and may provide a promising new oral treatment.

9 Nov 2004

Australian trial set to transform nursing home care

Medications trolleys in nursing homes may soon become mobile medical centres. The University of New South Wales has won a $300,000 grant to develop and trial a new point-of-care system that will allow nursing staff to manage medications, check patients’ clinical signs and streamline administration and clinical interaction with patients’ GPs.

8 Nov 2004

U.S. Patent for generating genetically altered antibody producing cell lines

Morphotek announced today the issuance of United States Patent 6,808,894 covering the generation of genetically enhanced antibody producer cell lines.

8 Nov 2004

The first test in humans of a bioartificial kidney

The first test in humans of a bioartificial kidney offers hope of the device's potential to save the lives of people with acute renal failure, researchers at the University of Michigan Health System report.

4 Nov 2004

Gene silencing may provide hope for leukemia sufferers

Ever since the approval of Gleevec in 2001, a cancer-cell-specific drug used to treat chronic myelogenous leukemia (CML), the field of cancer therapeutics has been rushing full speed into the era of so-called "targeted" medicines.

1 Nov 2004

Micro-array technology is revolutionising current drug development

Gene expression micro-array technology is benefiting all phases of the discovery, development and subsequent use of new cancer therapeutics

29 Oct 2004

National Cancer Institute symposium exploring the application of nanotechnology in the diagnosis, treatment and prevention of cancer

The Case Comprehensive Cancer Center, which includes The Cleveland Clinic Taussig Cancer Center and the Ireland Cancer Center at University Hospitals of Cleveland, will sponsor a National Cancer Institute symposium exploring the application of nanotechnology in the diagnosis, treatment and prevention of cancer.

25 Oct 2004

Potential new protein marker for prognosis of breast and ovarian cancer

The researchers matched tumor samples to outcomes in about 100 patients diagnosed with either breast or ovarian cancer and found that a low level of Rab25 protein on a patient's cancer sample was associated with a better clinical outcome in both cancer types.

24 Oct 2004

Benitec receives exclusive rights to use DNA technology pioneered at Stanford University for all RNAi therapeutic uses

Benitec has announced an exclusive licensing deal with Stanford University. Under the license, Benitec receives exclusive rights to use the Minicircle DNA technology pioneered at Stanford University for all RNAi therapeutic uses, with sub-licensing rights.

18 Oct 2004

Researchers have developed a novel drug-antidote pair

In a discovery that could give physicians more control over the actions of medications, researchers at Duke University Medical Center have developed a novel drug pair – a potent anti-coagulant with a matched "antidote."

18 Oct 2004

University of Cambridge executes exclusive patent licences and collaborative research and development agreement with Gene Networks International

The University of Cambridge has entered into two licence agreements with Gene Networks International (GNI), granting exclusive rights to Cambridge's intellectual property related to angiogenesis (the growth of new blood vessels) and inflammation that may have implications in the identification of new drug targets for a range of diseases.

13 Oct 2004

Research shows C. botulinum uses SONO to detect nitric oxide

A deadly bacterium's defense against a mortal molecular enemy illuminates the origins and structure of a vital protein involved in human cell signaling, University of Texas Medical School scientists report in Science Express.

8 Oct 2004

Transatlantic study to help damaged hearts repair themselves

A $6 million, five-year grant from the Parisian Fondation Leduq has set up a transatlantic effort to study ways to help damaged hearts repair themselves, using stem cells from bone marrow, bloodstream, and adult heart tissue.

6 Oct 2004

Prognostic factors influencing survival in patients with brain metastases identified

Allos Therapeutics has announced the presentation of new findings from its Phase 3 clinical trial of the investigational radiation sensitizer Efaproxyn (efaproxiral) in patients with brain metastases.

4 Oct 2004

A revolutionary approach to angiogenesis could make cancer treatment more effective at killing tumours

Dr. Olivier Feron and his team from the University of Louvain Medical School in Brussels have turned the whole concept of targeting tumour blood vessels on its head. Instead of the conventional approach of trying to starve tumour cells of the blood supply they need to grow, they are doing the opposite – opening up the tumour blood supply to allow better access for cancer drugs and more effective radiotherapy.

30 Sep 2004

Lycopene may be able to inhibit the growth of prostate tumours

A study by Dutch and German researchers has provided evidence that lycopene may be able to inhibit the growth of prostate tumours and that its effect may be enhanced if it is combined with vitamin E.

30 Sep 2004

Acne-like rash linked to effectiveness of new targeted cancer treatment – cetuximab

Acne is not a condition that anyone would welcome under normal circumstances, but an international study of a new targeted cancer treatment – cetuximab – has shown that patients who developed an acne-like rash responded better to the treatment than those who did not.

30 Sep 2004

Researchers show gossypol – a drug refined from cottonseed oil is a cancer treatment booster

New research has opened up the prospect that gossypol – a drug refined from cottonseed oil and previously tried and abandoned as a male contraceptive – could boost the effectiveness of treatment for prostate tumours and possibly other common cancers as well.

30 Sep 2004

New funding for Scottish scientists to tackle diseases such as asthma and multiple sclerosis

Scientists at the University of Aberdeen have been awarded £196,166 to help fund pioneering research, which is exploring a method of combating certain conditions and diseases such as asthma and multiple sclerosis.

29 Sep 2004

Therapeutics News and Research

Bretylium tosylate has unique benefits for patients with acute myocardial infarction

New studies demonstrate efficacy of novel Lipoxin analog in laboratory models of Crohn's disease

Australian trial set to transform nursing home care

U.S. Patent for generating genetically altered antibody producing cell lines

The first test in humans of a bioartificial kidney

Gene silencing may provide hope for leukemia sufferers

Micro-array technology is revolutionising current drug development

National Cancer Institute symposium exploring the application of nanotechnology in the diagnosis, treatment and prevention of cancer

Potential new protein marker for prognosis of breast and ovarian cancer

Benitec receives exclusive rights to use DNA technology pioneered at Stanford University for all RNAi therapeutic uses

Researchers have developed a novel drug-antidote pair

University of Cambridge executes exclusive patent licences and collaborative research and development agreement with Gene Networks International

Research shows C. botulinum uses SONO to detect nitric oxide

Transatlantic study to help damaged hearts repair themselves

Prognostic factors influencing survival in patients with brain metastases identified

A revolutionary approach to angiogenesis could make cancer treatment more effective at killing tumours

Lycopene may be able to inhibit the growth of prostate tumours

Acne-like rash linked to effectiveness of new targeted cancer treatment – cetuximab

Researchers show gossypol – a drug refined from cottonseed oil is a cancer treatment booster

New funding for Scottish scientists to tackle diseases such as asthma and multiple sclerosis

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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