Tumor Necrosis Factor News and Research

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β-damascone can function as an efficient modulator of dendritic cell-mediated functions

Dendritic cells (DCs) are important players of the immune system with important functions such as the identification of infectious pathogens, production of cytokines (chemical signalers of the immune system), presentation of antigens to activate T-cells, and more.

10 Feb 2023

Casein-based diet found to protect diabetic mice against autoimmunity

Researchers studied diet-commensal microbial interactions in autoimmunity.

10 Feb 2023

Recent findings on T-cell immunity induced by SARS-CoV-2 infection and vaccination in immunocompromised individuals

Researchers discussed studies that explored T-cell immunity induced by SARS-CoV-2 infection and COVID-19 vaccination in cancer patients, individuals with HIV, and recipients of solid organ transplants.

8 Feb 2023

Study shows activation of pulmonary macrophages by SARS-CoV-2 spike glycoprotein

In a recent study published in the International Journal of Molecular Sciences, researchers investigated the effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) glycoprotein on human lung macrophage (HLM) activation and angiotensin-converting enzyme 2 (ACE2) and transmembrane serine protease 2 (TMPRSS2) expression in human lung macrophages.

7 Feb 2023

Diet, microbial metabolites, and cytokine levels correlate with depression and anxiety symptoms in obese individuals

Researchers determine the association between diet, microbe-derived metabolites, and cytokine levels with anxiety and depression among obese adults.

6 Feb 2023

Cardiovascular risk in psoriasis, the association between psoriatic inflammation and atherosclerosis, and the cardiovascular-risk-reducing effects of biologics

Researchers explored the impact of biological interventions in reducing cardiovascular risk among psoriasis patients.

6 Feb 2023

A machine-learning approach to identify asthma subtypes based on molecular signatures

Researchers determine whether protein expression in nasal fluid samples could assist in the diagnosis of severe asthma subtypes.

31 Jan 2023

Repression of endothelial TLR3 is a potential mechanism of SARS-CoV-2 infection-associated lung vascular remodeling

Researchers investigated whether endothelial TLR3 insufficiency contributes to lung vascular remodeling induced by SARS-CoV-2.

30 Jan 2023

Disruption of the blood-brain barrier due to long COVID

Researchers explored the destruction of the blood-brain barrier (BBB) due to cognitive impairment associated with long coronavirus disease (COVID).

27 Jan 2023

Sex-specific patterns of cytokine activation in the hippocampus post-immunological challenge

Researchers evaluated sex-based differences among cytokine and chemokine networks in the hippocampus after systemic immunological challenge.

25 Jan 2023

Phase I trial results from AdaptVac's COVID capsid virus-like particle vaccine

In a recent study published in The Lancet Microbe journal, researchers described the effectiveness of a modular capsid virus-like coronavirus disease 2019 (COVID-19) vaccination.

22 Jan 2023

Immunological interactions between asthma, obesity, and the microbiota

This study summarizes the mechanisms associated with obesity-aggravated asthma.

18 Jan 2023

What factors are associated with successful dietary weight loss interventions?

A new study explored the factors governing the success of long- and short-term weight loss interventions.

18 Jan 2023

What are the major findings of long COVID research?

Researchers explored existing literature on long coronavirus disease (COVID). They highlighted key immunological findings, similarities with other diseases, symptoms, and associated pathophysiological mechanisms, and diagnostic and therapeutic options, including COVID-19 vaccinations.

17 Jan 2023

Preclinical study shows the therapeutic value of kinetin against SARS-CoV-2

Researchers investigated the ability of kinetin (N6-furfurylaminopurine, MB-905) to inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) proliferation in vitro.

17 Jan 2023

Researchers report that vectored expression of a high-affinity ACE2 microbody protein establishes a high degree of protection from SARS-CoV-2

Researchers evaluated the use of receptor decoys for SARS-CoV-2 based on soluble forms of ACE2 for immunological prophylaxis and management of COVID-19 through the use of AAV vectors.

16 Jan 2023

Tumor Necrosis Factor News and Research

β-damascone can function as an efficient modulator of dendritic cell-mediated functions

Casein-based diet found to protect diabetic mice against autoimmunity

Recent findings on T-cell immunity induced by SARS-CoV-2 infection and vaccination in immunocompromised individuals

Study shows activation of pulmonary macrophages by SARS-CoV-2 spike glycoprotein

Diet, microbial metabolites, and cytokine levels correlate with depression and anxiety symptoms in obese individuals

Cardiovascular risk in psoriasis, the association between psoriatic inflammation and atherosclerosis, and the cardiovascular-risk-reducing effects of biologics

A machine-learning approach to identify asthma subtypes based on molecular signatures

Repression of endothelial TLR3 is a potential mechanism of SARS-CoV-2 infection-associated lung vascular remodeling

Disruption of the blood-brain barrier due to long COVID

Sex-specific patterns of cytokine activation in the hippocampus post-immunological challenge

Phase I trial results from AdaptVac's COVID capsid virus-like particle vaccine

Immunological interactions between asthma, obesity, and the microbiota

What factors are associated with successful dietary weight loss interventions?

What are the major findings of long COVID research?

Preclinical study shows the therapeutic value of kinetin against SARS-CoV-2

Researchers report that vectored expression of a high-affinity ACE2 microbody protein establishes a high degree of protection from SARS-CoV-2

Silencing the immune evasion gene enhances cancer cells' susceptibility to immunotherapy

Mediterranean diet reduces dietary inflammation scores after six months

Review shows metformin usage to be associated with better COVID-19 outcomes

Free spike proteins in the blood appear to play a role in myocarditis post-COVID mRNA vaccine

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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