Tumor Necrosis Factor News and Research

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Scientists rewire mouse stem cells to fight inflammation caused by arthritis

Using new gene-editing technology, researchers have rewired mouse stem cells to fight inflammation caused by arthritis and other chronic conditions.

28 Apr 2017

‘Geneva signature’ evaluates safety and immunogenicity of promising anti-Ebola virus vaccine

An international team based at Geneva University Hospitals and at the University of Geneva, Switzerland, has succeeded in defining a "signature" composed of a small number of inflammatory markers that can be monitored in order to understand how a promising anti-Ebola virus vaccine stimulates the immune system.

19 Apr 2017

Researchers develop prognostic tool that predicts risk of kidney failure in diabetes patients

Researchers from Joslin Diabetes Center have developed a prognostic tool that accurately predicts the risk of end stage renal disease (ESRD) in patients with both type 1 and type 2 diabetes.

18 Apr 2017

Gut microbes cause age-associated inflammation and premature death, mice study shows

Gut microbes cause age-associated inflammation and premature death in mice, McMaster University researchers have found. The study could lead to new strategies to improve intestinal health and immune function in older adults.

12 Apr 2017

Tumor necrosis factor may help control blood pressure, study suggests

Investigators at the Ted Rogers Centre for Heart Research have discovered a surprising new role for tumor necrosis factor (TNF): namely, that it is a major regulator of small blood vessel function, the key determinant of blood pressure. The study is published online today in Nature Communications.

6 Apr 2017

Study provides new understanding of molecular mechanisms of HPV-induced tumors

The incidence of human papillomavirus (HPV)-associated (HPV+) head and neck squamous cell carcinoma (HNSCC) of the oropharynx has dramatically increased over the last decade and is now more frequently diagnosed than uterine cervical cancer in the United States.

31 Mar 2017

Research helps elucidate mechanisms behind low-level laser therapy in treating neuropathic pain

Low-level laser therapy has been shown by recent studies to be a non-invasive and effective alternative for treating neuropathic pain, a chronic condition caused by nerve damage, spinal cord injury or diseases such as diabetes.

28 Mar 2017

Scientists identify molecules that may be key to drug resistance in estrogen-driven breast cancers

Three-quarters of all breast cancer tumors are driven by the hormone estrogen. These tumors are frequently treated with drugs to suppress estrogen receptor activity, but unfortunately, at least half of patients do not respond to these treatments, leaving them with drug-resistant tumors and few options.

20 Mar 2017

Researchers develop new assay for measuring underlying autoimmunity in rheumatoid arthritis patients

Current treatments for rheumatoid arthritis relieve the inflammation that leads to joint destruction, but the immunologic defect that triggers the inflammation persists to cause relapses, according to research conducted at NYU Langone Medical Center and the University of Pittsburgh.

24 Feb 2017

Researchers reveal how inflammatory responses block fat cell conversion

Scientists at the University of Bonn have shown in mice that excess pounds can simply be melted away by converting unwanted white fat cells into energy-consuming brown slimming cells.

3 Jan 2017

New research offers valuable insight for developing more effective drugs to treat IBD

Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the intestine that includes Crohn's disease and ulcerative colitis.

22 Dec 2016

Scientists identify cell-surface receptor for progranulin

Progranulin is produced and secreted by most cells in the body. From skin to immune cells, brain to bone marrow cells, progranulin plays a key role in maintaining normal cellular function.

30 Nov 2016

Karolinska Institute biologist receives 2016 Naomi Berrie Award for excellence in diabetes research

Columbia University has awarded the 2016 Naomi Berrie Award for Outstanding Achievement in Diabetes Research to Peter Arner, MD, PhD, a Distinguished Professor in the Department of Medicine at the Karolinska Institute, whose studies on the turnover of fat tissue in the human body has revealed processes that contribute to obesity and diabetes.

23 Nov 2016

Arthritis drug induces response and remission in patients with Crohn's disease, study finds

Researchers at University of California San Diego School of Medicine have shown that ustekinumab, a human antibody used to treat arthritis, significantly induces response and remission in patients with moderate to severe Crohn's disease.

17 Nov 2016

UAB researchers show how aging and excess dietary fat lead to heart failure

In mouse experiments, University of Alabama at Birmingham researchers have shown how aging and excess dietary fat create signals that lead to heart failure after a heart attack.

17 Nov 2016

Preconsumption of red wine can prevent short-term vascular injury caused by smoking

Drinking red wine is widely regarded as protective against cardiovascular disease. A new report in The American Journal of Medicine found that a glass or two of red wine before lighting up a cigarette can counteract some of the short-term negative effects of smoking on blood vessels.

15 Nov 2016

Tumor Necrosis Factor News and Research

Scientists rewire mouse stem cells to fight inflammation caused by arthritis

‘Geneva signature’ evaluates safety and immunogenicity of promising anti-Ebola virus vaccine

Researchers develop prognostic tool that predicts risk of kidney failure in diabetes patients

Gut microbes cause age-associated inflammation and premature death, mice study shows

Tumor necrosis factor may help control blood pressure, study suggests

Study provides new understanding of molecular mechanisms of HPV-induced tumors

Research helps elucidate mechanisms behind low-level laser therapy in treating neuropathic pain

Scientists identify molecules that may be key to drug resistance in estrogen-driven breast cancers

Researchers develop new assay for measuring underlying autoimmunity in rheumatoid arthritis patients

Researchers reveal how inflammatory responses block fat cell conversion

New research offers valuable insight for developing more effective drugs to treat IBD

Scientists identify cell-surface receptor for progranulin

Karolinska Institute biologist receives 2016 Naomi Berrie Award for excellence in diabetes research

Arthritis drug induces response and remission in patients with Crohn's disease, study finds

UAB researchers show how aging and excess dietary fat lead to heart failure

Preconsumption of red wine can prevent short-term vascular injury caused by smoking

Virginia Tech and CytImmune Sciences develop more effective and less toxic cancer treatment

Status uncertainty may be risk factor for acute diseases, study shows

New study raises serious safety concerns in clinical use of caspase inhibitors for liver injury

Novartis gets three FDA approvals for expanded use of biologic drug to treat rare autoinflammatory diseases

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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