With the Xevo MRT Mass Spectrometer, users in both academia and industry may consistently produce outstanding science. This cutting-edge QTof provides sub-ppm mass accuracy and 100K FWHM resolution at 100 Hz for reliable identification and increased lab productivity.
Thanks to multi-reflecting time-of-flight (MRT) technology, mass resolution is stable throughout a wide m/z range, regardless of scan speed, even at the fastest acquisition rates. This technology is perfect for large cohort studies in biological research because it guarantees outstanding data quality for scientific interpretation.
A new level of assurance is unlocked by the Xevo MRT Mass Spectrometer, which gives every lab access to an analytical powerhouse.
Overview
Unlocking a new level of confidence by bringing an analytical powerhouse to every lab. Image Credit: Waters Corporation
Flexible system layout to fit your lab. Image Credit: Waters Corporation
- Regardless of acquisition rate, acquire at maximum sensitivity and resolution to guarantee that users can resolve analytes in intricate matrices for thorough scientific interpretation
- Investigate further at biologically significant concentrations with great mass accuracy
- Reduce time to result by combining state-of-the-art technology in a versatile benchtop platform with industry-leading chemistry, separations, and cutting-edge, pertinent informatics
- Provide superior experimental results and resolve the most difficult issues with remarkable system robustness and repeatability
- High resolution and speed can be attained without sacrificing analytical effectiveness
High-end technology to meet your most challenging analytical problems. Image Credit: Waters Corporation
Exceptional science for every lab, scientist, problem, question, and sample… solved. Image Credit: Waters Corporation
High resolution and speed without compromise
A representative triglyceride lipid at m/z 874 is provided at scan rates of 1, 5, 10 and 20 Hz, for which we can see that the mass resolution is maintained across all scan rates in the region of 80,000. Image Credit: Waters Corporation
The Xevo MRT Mass Spectrometer delivers an outstanding combination of 100,000 FWHM high mass resolving power and mass accuracy of less than 500 ppb, maintaining these capabilities regardless of acquisition rates, up to 100 Hz. Maximum performance boosts statistical power and results confidence when matched to throughput levels, which are important for intricate and difficult analyses.
Even at the fastest acquisition rates for MS and MS/MS data, multi-reflecting time-of-flight ensures confident identification of analytes across various samples and matrices, making it the perfect solution for metabolite profiling and discovery. This is in contrast to other high-resolution MS systems, which provide mass resolution consistent over a broad mass range independent of scan speed.
Driving efficiency through workflows
The waters_connect platform provides flexible data processing options, either using third-party applications via the waters_connect API or conversion of data sets to mzML file format. #https://mzio.io/#mzmine; §http://prime.psc.riken.jp/compms/msdial/main.html; and XCMS(TM) is a trademark of The Scripps Research Institute. Image Credit: Waters Corporation
Dedicated workflows that combine the outstanding data quality of the Xevo MRT Mass Spectrometer with column chemistries, separations, and informatics can help users make significant scientific discoveries more quickly. The waters_connect platform gives users the ability to handle and report data however they see fit.
With their industry-leading metabolomic, lipidomic, and metabolite identification software packages, MARS, Lipostar2, and MassMetaSite, respectively, Waters has teamed with Mass AnalyticaTM. Users can import the data into the appropriate software program for statistical analysis and analyte identification using the waters_connect Application Programming Interface (API) or the mzML* file format.
Every lab can seamlessly integrate technology and informatics with the help of the DATA Convert application within the waters_connect platform, which allows users to convert and export mzML file formats.
Unlocking a new level of confidence
The Xevo MRT Mass Spectrometer schematic. Image Credit: Waters Corporation
Waters has taken the state-of-the-art technology first introduced in the SELECT SERIES MRT and scaled the raw power and resolution at speed into a small, adaptable benchtop platform to tackle users' difficulties.
The Xevo MRT Mass Spectrometer was designed to address the most difficult challenges by integrating cutting-edge technology onto a tabletop platform. With its dual gain analog-to-digital converter, the innovative collection technology ensures remarkable quality data with consistent resilience and repeatability over a wide dynamic range.
For the best MS/MS performance, the MRT mass analyzer's 4 m flight path with 8 reflections in total can reach up to 100,000 FWHM resolution at scan speeds as high as 100 Hz.
It is time to produce outstanding science on a daily basis.