Measure all 96 wells in just 1 minute using Raman spectroscopy. Non-destructive sampling allows real-time reaction monitoring, while high spectral quality ensures detailed compound characterization.
High-throughput Raman screening (Raman HTS) is a drug discovery technique that enables automated, rapid analysis of 96- to 384-well liquid plates.
Image Credit: HORIBA
No more bulky Raman microscopes for plate reading - enjoy a fully automated workflow featuring a motorized door, dedicated software, and server access. Seamlessly integrate the Raman solutions with the automated liquid handling systems.
Rapid Raman Plate Reader – HTS with Raman will speed up your drug developments!
Video Credit: HORIBA
Why pursue lengthy HPLC analyses when Raman spectra can quickly deliver trends in bioprocess monitoring?
RPR Control Software includes OPC-UA and REST API interfaces, ensuring seamless interoperability with standard pharmaceutical systems.
The patent-pending Rapid Raman reading technology, combined with the integrated Plate Heater, enables real-time reaction monitoring with exceptional speed. Simply program a quick well plate transfer into the PoliSpectra RPR - complete Raman reading takes just 1 to a few minutes per plate. The robotic handler can then promptly return the plate to the liquid handler or dispenser to continue the reactions, all before the plate begins to cool.
The RPR dedicated 96-well plate reader delivers a powerful combination of speed, simplicity, and performance to enhance early formulation development.
Instantly gain insights with real-time reaction trend data.
Features
- Exceptional well-to-well signal reproducibility
- Ultra high-speed performance: scans 96 wells in under 1 minute at 500 ms exposure per well
- Ultra-low crosstalk between wells
- Fully compatible with liquid handling systems for automated sampling
“PoliSpectra RPR is a high-speed, nondestructive, and effective screening tool ready to be integrated into High-Throughput Screening (HTS) Processes in Pharmaceutical Industry.”
Specifications
Laser. Source: HORIBA
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| Laser Wavelength |
Choose from 532 nm and 785 nm |
| Laser power for 532 nm |
up to 150 mW |
| Laser power for 785 nm |
up to 500 mW |
| Laser Power adjustment |
Software controlled |
Scientific camera. Source: HORIBA
| . |
. |
| Deep Cooled Camera |
< -25 °C TE-cooling (from +20 °C ambient) |
| Type of Scientific Sensor |
CCD or sCMOS |
Modular Raman spectrometer. Source: HORIBA
| |
532 Raman Spectrometer |
785 Raman Spectrometer |
| Resolution |
1.7 cm-1/pixel |
1.6 cm-1/pixel |
| Spectral Coverage |
From: 400 cm-1 To: 3150 cm-1 |
From: 200 cm-1 To: 3400 cm-1 |
RPR system specifications. Source: HORIBA
| . |
. |
| Reading Speed |
96 wells in < 1 minute (@532 nm) @ 500 msec exposure time per well |
| Plate Format: |
96 wells (custom wells on request) |
| Self-calibration |
Automatic (on programmable timing) |
| Door |
Motorized for robot compatibility |
| Server Control |
OPC-UA |
| Footprint |
28.2" X 19.2" (71.6 cm x 48.8 cm) |