SPR Validated Fc Receptor Proteins

Key Features of Fc Receptor Proteins

High Purity

ACROBiosystems’ production team performs both SDS-PAGE and HPLC analyses to the Fc receptors to ensure that their product exhibits the highest level of purity. Users should recognize that it is essential to use a monomeric Fc receptor, as this type of receptor represents its natural state.

The formation of oligomers during the production of Fc receptors can result in an artificially-enhanced binding interaction as a result of the avidity effect. To avoid this type of effect from occurring, ACROBiosystems has established strict internal control standards that determine the monomer purity using HPLC testing. ACROBiosystems only releases batches that meet all monomer purity requirements.

Bioactivity Validated by SPR

The binding affinity between two molecules can be determined using various methods. However, evaluating the Fc receptor interaction is typically achieved by SPR.

This method preference can be attributed to the fact that traditional ELISA techniques are not appropriate for low-affinity receptors (such as CD16 and CD32). The ACROBiosystems’ Quality Control (QC) team utilizes the Biacore platform to test all Fc receptors against reference antibodies.

High Batch-to-Batch Consistency

ACROBiosystems routinely applies rigorous quality control measures to ensure that all Fc receptors exhibit consistent performance rates. Any batch variation among tested samples is negligible.

Product List

Molecule Sign Species Tag
FcRn (FCGRT & B2M) FCM-H5286 Human C-6×His | C-Strep II
Human C-6×His | C-Strep II
Human C-Avi & C-6×His | C-Strep II
FCM-C5284 Cynomolgus / Rhesus macaque C-10×His | C-Strep II
Cynomolgus / Rhesus macaque C-Avi & C-10×His | C-Strep II
FCM-M52W2 Mouse C-10×His | C-Twin-Strep
Mouse C-Avi & C-10×His | C-Twin-Strep
FCM-R5287 Rat C-6×His | C-Strep II
Rat C-Avi & C-10×His | C-Strep II
Bovine C-10×His & C-Avi | Native
Feline C-10×His & C-Avi | Native
FCM-P5280 Porcine C-6×His | C-Strep II
Fc gamma RIIIA / CD16a (F176) CDA-H5220 Human C-10xHis
Human C-Avi & C-10xHis
Fc gamma RIIIA / CD16a (V176) CD8-H52H4 Human C-10xHis
Human C-Avi & C-10xHis
CDB-H5227 Human C-10xHis
Human C-10xHis & C-Avi
CDB-H5222 Human C-10xHis
Human C-10xHis & C-Avi
Fc gamma RIII / CD16 FC6-C52H9 Cynomolgus C-10xHis
Cynomolgus C-10xHis & C-Avi
CDA-M52H8 Mouse C-10xHis
Fc gamma RIIA / CD32a (H167) CD1-H5223 Human C-9xHis
Human C-Avi & C-10×His
Fc gamma RIIA / CD32a (R167) CDA-H5221 Human C-9xHis
Human C-Avi & C-10×His
Fc gamma RIIB / CD32b CDB-H5228 Human C-8xHis
Human C-Avi & C-10×His
CDB-M52H7 Mouse C-10xHis
Fc gamma RI / CD64 FCA-H52H2 Human C-10xHis
  C-10xHis & C-Avi
CD4-M5227 Mouse C-10xHis
CD23 CD3-H5249 Human N-10xHis
Human N-10xHis & N-Avi

Other Equipment by this Supplier

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