Monoclonal Antibodies for Rituximab, Cetuximab and Adalimumab Molecules

About the Anti-Rituximab Antibodies

  • Source
    • The source of the mouse monoclonal antibody is a hybridoma that has been produced from the fusion of SP2/0 myeloma and B-lymphocytes that were previously obtained from a mouse immunized with Rituximab F(ab’)2
  • Isotype
    • IgG1/kappa
  • Specificity
    • Specifically recognizes Rituximab
    • No cross reactivity with other humanized antibodies occurs
  • Purity
    • >95% (as determined by SDS-PAGE)
  • Formulation
    • This antibody has been lyophilized from 0.22 µm filtered solution in 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, with a total pH of 7.5.
    • Trehalose is typically added as a protectant prior to lyophilization
  • Reconstitution
    • It is recommended that users refer to the Certificate of Analysis for information regarding reconstitution protocol
  • Storage
    • For long-term storage, it is recommended that this product is stored at its lyophilized state at -20 °C or lower
    • Avoid repeated freeze-thaw cycles
    • No activity loss was observed after storage in the following conditions:
      • 4-8 °C for 12 months in its lyophilized state
      • -70 °C for 3 years under sterile conditions following reconstitution.

About the Anti-Cetuximab Antibodies

  • Source
    • The source of the mouse monoclonal antibody is a hybridoma that has been produced from the fusion of SP2/0 myeloma and B-lymphocytes that were previously obtained from a mouse immunized with Cetuximab F(ab’)2
  • Isotype
    • IgG1/kappa
  • Specificity
    • Specifically recognizes Cetuximab
    • No cross reactivity with other humanized antibodies occurs
  • Purity
    • >95% as determined by SDS-PAGE
  • Formulation
    • This antibody has been lyophilized from 0.22 µm filtered solution in 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, with a total pH of 7.5
    • Trehalose is typically added as a protectant prior to lyophilization
  • Reconstitution
    • It is recommended that users refer to the Certificate of Analysis for information regarding reconstitution protocol
  • Storage
    • For long-term storage, it is recommended that this product is stored at its lyophilized state at -20 °C or lower
    • Avoid repeated freeze-thaw cycles
    • No activity loss was observed after storage in the following conditions:
      • 4-8 °C for 12 months in its lyophilized state
      • -70 °C for 3 years under sterile conditions following reconstitution

About the Anti-Adalimumab Antibodies

  • Source
    • The source of the mouse monoclonal antibody is a hybridoma that has been produced from the fusion of SP2/0 myeloma and B-lymphocytes that were previously obtained from a mouse immunized with Adalimumab F(ab’)2
  • Isotype
    • IgG1/kappa
  • Specificity
    • Specifically recognizes Adalimumab
    • No cross-reactivity with other humanized antibodies occurs
  • Purity
    • >95% as determined by SDS-PAGE
  • Formulation
    • This antibody has been lyophilized from 0.22 µm filtered solution in 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, with a total pH of 7.5
    • Trehalose is typically added as a protectant prior to lyophilization
  • Reconstitution
    • It is recommended that users refer to the Certificate of Analysis for information regarding reconstitution protocol
  • Storage
    • For long-term storage, it is recommended that this product is stored at its lyophilized state at -20 °C or lower
    • Avoid repeated freeze-thaw cycles
    • No activity loss was observed after storage in the following conditions:
      • 4-8 °C for 12 months in its lyophilized state
      • -70 °C for 3 years under sterile conditions following reconstitution.