Monoclonal Antibodies for Rituximab, Cetuximab and Adalimumab Molecules

About the Anti-Rituximab Antibodies

• Source
  • The source of the mouse monoclonal antibody is a hybridoma that has been produced from the fusion of SP2/0 myeloma and B-lymphocytes that were previously obtained from a mouse immunized with Rituximab F(ab’)₂
• Isotype
  • IgG1/kappa
• Specificity
  • Specifically recognizes Rituximab
  • No cross reactivity with other humanized antibodies occurs
• Purity
  • >95% (as determined by SDS-PAGE)
• Formulation
  • This antibody has been lyophilized from 0.22 µm filtered solution in 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, with a total pH of 7.5.
  • Trehalose is typically added as a protectant prior to lyophilization
• Reconstitution
  • It is recommended that users refer to the Certificate of Analysis for information regarding reconstitution protocol
• Storage
  • For long-term storage, it is recommended that this product is stored at its lyophilized state at -20 °C or lower
  • Avoid repeated freeze-thaw cycles
  • No activity loss was observed after storage in the following conditions:
    • 4-8 °C for 12 months in its lyophilized state
    • -70 °C for 3 years under sterile conditions following reconstitution.

About the Anti-Cetuximab Antibodies

• Source
  • The source of the mouse monoclonal antibody is a hybridoma that has been produced from the fusion of SP2/0 myeloma and B-lymphocytes that were previously obtained from a mouse immunized with Cetuximab F(ab’)₂
• Isotype
  • IgG1/kappa
• Specificity
  • Specifically recognizes Cetuximab
  • No cross reactivity with other humanized antibodies occurs
• Purity
  • >95% as determined by SDS-PAGE
• Formulation
  • This antibody has been lyophilized from 0.22 µm filtered solution in 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, with a total pH of 7.5
  • Trehalose is typically added as a protectant prior to lyophilization
• Reconstitution
  • It is recommended that users refer to the Certificate of Analysis for information regarding reconstitution protocol
• Storage
  • For long-term storage, it is recommended that this product is stored at its lyophilized state at -20 °C or lower
  • Avoid repeated freeze-thaw cycles
  • No activity loss was observed after storage in the following conditions:
    • 4-8 °C for 12 months in its lyophilized state
    • -70 °C for 3 years under sterile conditions following reconstitution

About the Anti-Adalimumab Antibodies

• Source
  • The source of the mouse monoclonal antibody is a hybridoma that has been produced from the fusion of SP2/0 myeloma and B-lymphocytes that were previously obtained from a mouse immunized with Adalimumab F(ab’)₂
• Isotype
  • IgG1/kappa
• Specificity
  • Specifically recognizes Adalimumab
  • No cross-reactivity with other humanized antibodies occurs
• Purity
  • >95% as determined by SDS-PAGE
• Formulation
  • This antibody has been lyophilized from 0.22 µm filtered solution in 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, with a total pH of 7.5
  • Trehalose is typically added as a protectant prior to lyophilization
• Reconstitution
  • It is recommended that users refer to the Certificate of Analysis for information regarding reconstitution protocol
• Storage
  • For long-term storage, it is recommended that this product is stored at its lyophilized state at -20 °C or lower
  • Avoid repeated freeze-thaw cycles
  • No activity loss was observed after storage in the following conditions:
    • 4-8 °C for 12 months in its lyophilized state
    • -70 °C for 3 years under sterile conditions following reconstitution.