Drug Discovery & Pharmaceuticals

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Insilico Medicine's AI-designed drug ISM3412 receives FDA IND approval

Clinical stage artificial intelligence (AI)-driven drug discovery company Insilico Medicine announces that it has received approval from the U.S. Food and Drug Administration for its Investigational New Drug application for ISM3412, a small molecule inhibitor of MAT2A for the potential treatment of MTAP deleted cancers designed with Insilico's generative AI platform.

25 Apr 2024

Innovative malaria prodrug targets liver, enhances efficacy while reducing toxicity, preclinical studies show

Tafenoquine, a prodrug that could fulfill the criteria for a mass eradication campaign.

23 Apr 2024

Top pharmaceutical company evaluates Optimer for precision liver medicine

Optimer delivery vehicle has been shipped to a pharma partner for external evaluation.

From Aptamer Group 22 Apr 2024

AI techniques massively accelerate the search for Parkinson's disease treatments

Researchers have used artificial intelligence techniques to massively accelerate the search for Parkinson's disease treatments.

17 Apr 2024

ELRIG UK and SRG announce partnership to advance life science professionals in drug discovery

The European Laboratory Research & Innovation Group (ELRIG) UK, a not-for-profit, volunteer-led organization for the drug discovery community, today entered into a partnership with SRG, leaders in life science recruitment, to support the advancement of science professionals in their careers.

From ELRIG (UK) Ltd. 17 Apr 2024

MD Anderson and CureVac collaborate on mRNA-based cancer vaccines

The University of Texas MD Anderson Cancer Center and CureVac N.V. today announced a co-development and licensing agreement to develop novel mRNA-based cancer vaccines.

16 Apr 2024

Deciphering the molecular interactions of opioid receptors: Implications for drug design

Drugs that target opioid receptors sometimes have severe side effects. Thousands of people around the world die every day from overdoses involving opioids such as fentanyl.

13 Apr 2024

Insilico Medicine's AI-driven approach yields promising PTPN2/N1 inhibitor for cancer immunotherapy

In recent years, cancer immunotherapy, exemplified by PD-1 and its ligand PD-L1 blockade, has made remarkable advances.

13 Apr 2024

Metrion Biosciences enhances High Throughput Screening services with access to Enamine compound libraries

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From Metrion Biosciences Limited 11 Apr 2024

Researchers create novel drug that can prevent flu-induced lung injury

Infection with the influenza virus leads to lung injury through inflammation over-activation that causes collateral damage to cells required for breathing.

10 Apr 2024

Language model uses powers of semantic representation to design more effective mRNA vaccines

The same class of artificial intelligence that made headlines coding software and passing the bar exam has learned to read a different kind of text -; the genetic code.

5 Apr 2024

Innovative molecular biology technique used to identify targets for Schistosoma mansoni vaccine candidates

Researchers in Brazil have used an innovative technique in molecular biology to identify targets for candidate vaccines against Schistosoma mansoni, the parasite that causes schistosomiasis.

2 Apr 2024

An ActRIIA fusion protein got FDA approved for PAH treatment

On March 26th, the US FDA granted approval for Merck’s WINREVAIR™ (sotatercept-csrk), marking a significant milestone in pulmonary arterial hypertension (PAH) treatment. PAH, characterized by elevated blood pressure in the arteries connecting the heart and lungs, poses a grave risk of heart failure.

From Sino Biological Inc. 28 Mar 2024

Drug Discovery & Pharmaceuticals

Insilico Medicine's AI-designed drug ISM3412 receives FDA IND approval

Innovative malaria prodrug targets liver, enhances efficacy while reducing toxicity, preclinical studies show

Top pharmaceutical company evaluates Optimer for precision liver medicine

AI techniques massively accelerate the search for Parkinson's disease treatments

ELRIG UK and SRG announce partnership to advance life science professionals in drug discovery

MD Anderson and CureVac collaborate on mRNA-based cancer vaccines

Deciphering the molecular interactions of opioid receptors: Implications for drug design

Insilico Medicine's AI-driven approach yields promising PTPN2/N1 inhibitor for cancer immunotherapy

Metrion Biosciences enhances High Throughput Screening services with access to Enamine compound libraries

Researchers create novel drug that can prevent flu-induced lung injury

Language model uses powers of semantic representation to design more effective mRNA vaccines

Innovative molecular biology technique used to identify targets for Schistosoma mansoni vaccine candidates

An ActRIIA fusion protein got FDA approved for PAH treatment

Generative AI revolutionizes antibiotic development against resistant pathogens

AI-based analysis uncovers two plant extracts with potential as GLP-1 agonist weight loss pills

New compound shows promise as a more effective treatment for schistosomiasis

New compound extracted from African catfish skin mucas exhibits powerful antibacterial properties

bioXcelerate launches breakthrough AI tool for faster drug discovery

Generative artificial intelligence model can easily design billions of novel antibiotics

Revolutionizing cysteine-rich peptide production for drug discovery

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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