Histology & Microscopy

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Avalanching nanoparticles may advance real-time bioimaging of cell's organelles and proteins

Since the earliest microscopes, scientists have been on a quest to build instruments with finer and finer resolution to image a cell's proteins - the tiny machines that keep cells, and us, running.

14 Jan 2021

New fluorescence microscopy technique produces nanoscale 3D images of living cells

A new fluorescence microscopy technique has produced the world's first nanoscale 3D images of molecules in a whole, living cell, researchers at KTH Royal Institute of Technology reported.

12 Jan 2021

Researchers develop improved process for large-scale electron microscopy to visualize small structures

How are networks of neurons connected to make functional circuits? This has been a long-standing question in neuroscience. To answer this fundamental question, researchers from Boston Children's Hospital and Harvard Medical School developed a new way to study these circuits and in the process learn more about the connections between them.

12 Jan 2021

Researchers demonstrate SARS-CoV-2 infection in human lung bronchioalveolar tissue model

Development of an in vitro human-derived tissue model for studying virus infection and disease progression in the alveolar cells of the lungs responsible for oxygen and carbon dioxide exchange with the blood might enable the study of possible therapies for acute respiratory distress syndrome (ARDS) triggered by SARS-CoV-2.

11 Jan 2021

Glycylation essential to keep sperm swimming in a straight line, shows study

One essential component of each eukaryotic cell is the cytoskeleton. Microtubules, tiny tubes consisting of a protein called tubulin, are part of this skeleton of cells.

7 Jan 2021

Comprehensive review details the evolution of surgical microscopes

A clear view of anatomical structures is vital for the success of surgery--especially in microsurgery where narrow anatomical cavities or proximity to vulnerable organs and tissues can pose significant risks to patient health.

5 Jan 2021

Novel imaging method reveals in vivo localization of antibiotics in infected lung tissues

Researchers at the Francis Crick Institute and the University of Western Australia have developed a new imaging method to see where antibiotics have reached bacteria within tissues.

5 Jan 2021

Self-learning algorithms can help analyze biological image data

Imaging techniques enable a detailed look inside an organism. But interpreting the data is time-consuming and requires a great deal of experience.

28 Dec 2020

Gene-regulating snippet of RNA may contribute to breast cancer metastasis

Cold Spring Harbor Laboratory (CSHL) scientists have discovered a gene-regulating snippet of RNA that may contribute to the spread of many breast cancers.

22 Dec 2020

Stem cells in the brain divide over months to create new nerve cells

For the first time, scientists at the University of Zurich have been able to observe stem cells in the adult mouse brain that divide over the course of several months to create new nerve cells. The study shows that brain stem cells are active over a long period, and thus provides new insights for stem cell research.

21 Dec 2020

Novel microcopy methods used to study tiny traction forces during T-cell activation

Highly complicated processes constantly take place in our body to keep pathogens in check: The T-cells of our immune system are busy searching for antigens - suspicious molecules that fit exactly into certain receptors of the T-cells like a key into a lock.

21 Dec 2020

Research reveals development stages of plaques in Alzheimer's disease

One cannot simply look inside someone else’s head. This makes it difficult to understand what is happening in the brains of people with dementia. A new method offers insights.

21 Dec 2020

New microscope could allow surgeons to inspect tumor margins within minutes

When surgeons remove cancer, one of the first questions is, "Did they get it all?" Researchers from Rice University and the University of Texas MD Anderson Cancer Center have created a new microscope that can quickly and inexpensively image large tissue sections, potentially during surgery, to find the answer.

18 Dec 2020

Penn State engineers find link between nitric oxide expressing neurons and arterial dilation

Neurons control blood flow in tiny vessels in the brain, but researchers know little about this relationship.

16 Dec 2020

Researchers study the mechanisms of skin aging

The ageing process is most apparent on the skin. In the newly opened "SKINMAGINE" (Multimodal Imaging of Aging and Senescence of the Skin) Christian Doppler Laboratory, dermatologists from MedUni Vienna have joined forces with biotechnologists from the University of Natural Resources and Applied Life Sciences Vienna and chemists from Vienna University of Technology, as well as the company Chanel, to study the interaction of metabolism, cellular communication and cellular quality control in skin ageing accelerated by environmental stress.

16 Dec 2020

New consortium aims to understand principles underlying the formation of coronaviruses

The University of California, Riverside, is the recipient of a 2021 UC Multicampus Research Programs and Initiatives, or MRPI, award allowing the campus to put together a UC Coronavirus Assembly Research Consortium.

9 Dec 2020

Research illuminates regulatory mechanism of ubiquitin-proteasome system in DNA damage repair

An international research team has clarified the regulatory mechanism of the ubiquitin-proteasome system in recognizing and repairing DNA that has been damaged by ultraviolet (UV) light.

8 Dec 2020

CRISPR-based test could provide rapid, low-cost testing to help control COVID-19 spread

Imagine swabbing your nostrils, putting the swab in a device, and getting a read-out on your phone in 15 to 30 minutes that tells you if you are infected with the COVID-19 virus.

5 Dec 2020

Expansion microscopy allows imaging of cell membranes in super resolution

For the first time ever, expansion microscopy allows the imaging of even the finest details of cell membranes. This offers new insights into bacterial and viral infection processes.

2 Dec 2020

Researchers reveal how SARS-CoV-2 reaches the brain

Using post-mortem tissue samples, a team of researchers from Charité - Universitätsmedizin Berlin have studied the mechanisms by which the novel coronavirus can reach the brains of patients with COVID-19, and how the immune system responds to the virus once it does.

30 Nov 2020

Histology & Microscopy

Avalanching nanoparticles may advance real-time bioimaging of cell's organelles and proteins

New fluorescence microscopy technique produces nanoscale 3D images of living cells

Researchers develop improved process for large-scale electron microscopy to visualize small structures

Researchers demonstrate SARS-CoV-2 infection in human lung bronchioalveolar tissue model

Glycylation essential to keep sperm swimming in a straight line, shows study

Comprehensive review details the evolution of surgical microscopes

Novel imaging method reveals in vivo localization of antibiotics in infected lung tissues

Self-learning algorithms can help analyze biological image data

Gene-regulating snippet of RNA may contribute to breast cancer metastasis

Stem cells in the brain divide over months to create new nerve cells

Novel microcopy methods used to study tiny traction forces during T-cell activation

Research reveals development stages of plaques in Alzheimer's disease

New microscope could allow surgeons to inspect tumor margins within minutes

Penn State engineers find link between nitric oxide expressing neurons and arterial dilation

Researchers study the mechanisms of skin aging

New consortium aims to understand principles underlying the formation of coronaviruses

Research illuminates regulatory mechanism of ubiquitin-proteasome system in DNA damage repair

CRISPR-based test could provide rapid, low-cost testing to help control COVID-19 spread

Expansion microscopy allows imaging of cell membranes in super resolution

Researchers reveal how SARS-CoV-2 reaches the brain

Could a diet high in carbohydrates increase your risk of heart disease?

What makes viruses infectious?

Disinfectants could be helping bacteria to become resistant

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