Histology & Microscopy

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Intellicule secures $217,941 SBIR Phase I grant to develop biomolecular modeling software

Intellicule, a software company whose solutions determine the 3D structures of biomolecules imaged with cryogenic-electron microscopy (cryo-EM), has received a $217,941 Small Business Innovation Research (SBIR) Phase I grant from the National Institutes of Health.

8 Dec 2025

New atomic structure reveals how NBCn1 transporter protein aids breast cancer cell survival

UCLA scientists have characterized the structure and function of a key survival protein in breast cancer cells that helps explain how these tumors resist environmental stress and thrive in acidic, low-oxygen environments that would normally be toxic to healthy cells.

5 Dec 2025

Study shines light on how P2X4 receptor can be inhibited

A study carried out by the University of Bonn and the University Hospital Bonn throws light on how an important receptor can be inhibited.

5 Dec 2025

Researchers capture high-resolution footage of flu viruses entering human cells

For the first time, researchers have observed live and in high resolution how influenza viruses infect living cells. This was possible thanks to a new microscopy technique, which could now help to develop antiviral therapies in a more targeted manner.

4 Dec 2025

Stem cells reshape in response to electrical signals, study reveals

Scientists in Melbourne have discovered how tiny electrical pulses can steer stem cells as they grow, opening the door to new improved ways of creating new tissues, organs, nerves and bones.

3 Dec 2025

Breakthrough platform reveals the choreography of mammalian transcription

Life's instructions are written in DNA, but it is the enzyme RNA polymerase II (Pol II) that reads the script, transcribing RNA in eukaryotic cells and eventually giving rise to proteins.

27 Nov 2025

Researchers capture a ribozyme in motion for the first time

RNA is a central biological macromolecule, now widely harnessed in medicine and nanotechnology. Like proteins, RNA function often depends on its precise three-dimensional structure.

27 Nov 2025

New imaging protocol captures mouse brain cell connections in precise detail

An international team of researchers led by the Francis Crick Institute, working with the Paul Scherrer Institute, have developed a new imaging protocol to capture mouse brain cell connections in precise detail.

27 Nov 2025

Researchers uncover how a key transcription factor reads DNA in human cells

With a new study in the journal Cell, researchers at Stanford University and Stockholm University have contributed to increased knowledge about gene regulation in human cells.

26 Nov 2025

New imaging method reveals nanodomains inside ALS-linked protein droplets

Inside the cell reside many tiny assembly factories and warehouses that gather together all of the proteins and RNAs-which carry out instructions from our DNA-that a living being needs.

26 Nov 2025

Researchers use "zap-and-freeze" technique to watch hard-to-see brain cell communications

Researchers at Johns Hopkins Medicine say they have used a "zap-and-freeze" technology to watch hard-to-see brain cell communications in living brain tissue from mice and humans.

25 Nov 2025

New insights into ribosome collisions and stress response

LMU researchers uncover the mechanism by which ribosomes raise alarms in the cell.

24 Nov 2025

Right-handed helical motion of malaria parasites revealed

With victims numbering in the millions, malaria is an infectious disease caused by the bite of a mosquito carrying the malaria parasite.

24 Nov 2025

Cryo-EM reveals how proteins are protected during synthesis

Proteins are often called the building blocks of cells, but even those building blocks need to be built. One of the most important steps in the process of building proteins is glycosylation, when sugar molecules (glycans) are attached to the maturing protein.

19 Nov 2025

Automated system relies on imaging droplets of biofluids for disease diagnosis

Not long ago, the idea of diagnosing a disease with a droplet of blood was considered a pipe dream. Today, this technology could soon become a reality.

19 Nov 2025

Generative AI tool enhances accuracy in detecting abnormal blood cells

An AI tool that can analyze abnormalities in the shape and form of blood cells, and with greater accuracy and reliability than human experts, could change the way conditions such as leukemia are diagnosed.

19 Nov 2025

Hiiragi group and Prevedel group collaborate with Prospective Instruments to pioneer intravital multiphoton microscopy for early embryo research

Prof. Takashi Hiiragi (Hubrecht Institute), Dr. Robert Prevedel (European Molecular Biology Laboratory), and Dr. Lukas Krainer (Prospective Instruments) have launched an interdisciplinary collaboration to develop a novel intravital microscopy platform for studying mammalian embryo implantation.

13 Nov 2025

New insights into how endoplasmic reticulum and lysosomes coordinate protein production

Janelia researchers have uncovered a novel way that two of the structures inside cells-the endoplasmic reticulum (ER) and lysosomes-coordinate the production of proteins, highlighting how interactions between organelles are important for regulating cellular processes.

11 Nov 2025

Researchers identify a previously unknown cellular mechanism crucial to coronavirus replication

The discovery could serve as a starting point for antiviral strategies. A research team at Ruhr University Bochum, Germany, has identified a previously unknown cellular mechanism crucial to the replication of coronaviruses: c-Jun N-terminal kinase (JNK) is activated during infection with human coronavirus HCoV-229E and mediates the phosphorylation of the viral nucleocapsid (N) protein, an integral step in the virus cycle.

7 Nov 2025

New AI-assisted atlas can help visualize the human brain in unprecedented detail

A new AI-assisted brain atlas that can help visualize the human brain in unprecedented detail has been developed by UCL researchers, in a major step forward for neuroscience and neuroimaging.

5 Nov 2025

Histology & Microscopy

Intellicule secures $217,941 SBIR Phase I grant to develop biomolecular modeling software

New atomic structure reveals how NBCn1 transporter protein aids breast cancer cell survival

Study shines light on how P2X4 receptor can be inhibited

Researchers capture high-resolution footage of flu viruses entering human cells

Stem cells reshape in response to electrical signals, study reveals

Breakthrough platform reveals the choreography of mammalian transcription

Researchers capture a ribozyme in motion for the first time

New imaging protocol captures mouse brain cell connections in precise detail

Researchers uncover how a key transcription factor reads DNA in human cells

New imaging method reveals nanodomains inside ALS-linked protein droplets

Researchers use "zap-and-freeze" technique to watch hard-to-see brain cell communications

New insights into ribosome collisions and stress response

Right-handed helical motion of malaria parasites revealed

Cryo-EM reveals how proteins are protected during synthesis

Automated system relies on imaging droplets of biofluids for disease diagnosis

Generative AI tool enhances accuracy in detecting abnormal blood cells

Hiiragi group and Prevedel group collaborate with Prospective Instruments to pioneer intravital multiphoton microscopy for early embryo research

New insights into how endoplasmic reticulum and lysosomes coordinate protein production

Researchers identify a previously unknown cellular mechanism crucial to coronavirus replication

New AI-assisted atlas can help visualize the human brain in unprecedented detail

Bioprocess Efficiency with Cell Density Monitoring

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

Extending the reach of Amperia™

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