Histology & Microscopy

RSS

Cryo-electron microscopy offers an unprecedented view of gene transcription

The enzyme RNA polymerase (RNAP) carries out transcription, copying DNA into RNA. It's the first step in gene expression, and a process fundamental to all life.

30 Apr 2026

Cryo-expansion microscopy reveals three-dimensional organization of killer T cells

Cytotoxic T lymphocytes are the body's specialized "killer" cells, precisely eliminating infected or cancerous cells.

29 Apr 2026

Detailed images reveal DNA repair mechanism in cancer-related proteins

Scientists have captured the most detailed structural images to date of a specific type of protein's DNA repair process, a finding that could reveal ways to inhibit the effects of BRCA1 and BRCA2 mutations that heighten the risk for breast, ovarian and other cancers.

28 Apr 2026

New cytometer measures cell stiffness to improve disease diagnosis

Researchers from Brown University and their collaborators have developed a new way to measure the properties of cells - an important development, they say, because accurate measurements of changes in cell elasticity can be used to better understand diseases, diagnose patient symptoms and provide more accurate prognoses.

25 Apr 2026

Epigenome proteins shape dynamic gene expression beyond simple on-off

A new study finds the proteins responsible for controlling which genes are expressed in a genome do more than simply turn a gene on or off.

21 Apr 2026

New imager separates UV and infrared light to find cancerous nodes

Researchers have developed a compact camera that captures ultraviolet, near-infrared and visible images using a single chip. Inspired by the multiwavelength vision capability of the mantis shrimp, the camera could help surgeons identify lymph nodes connected to a tumor and assess whether cancer has spread to them, making cancer surgery safer and less invasive.

17 Apr 2026

New imaging technique captures ultrafast microscopic processes with unprecedented detail

Researchers have developed a new imaging technique that captures more information about ultrafast processes in the microscopic world than was previously possible.

10 Apr 2026

Dynamic binding of linker histone H1 shapes flexible chromatin organization

DNA inside the nucleus is not packed as a rigid regular fiber-linker histone H1 dynamically binds and loosely "glues" nucleosomes together, creating a dynamic, fluid organization that can still support essential genome functions.

9 Apr 2026

Study reveals bile as reservoir for microplastics in humans

Plastic pollution has become one of the defining environmental issues of modern life, and microplastics are now known to enter the body through food, drink, and air.

6 Apr 2026

Deep UV microscopy enables label-free T cell characterization

A team of researchers at the Georgia Institute of Technology and Emory University has developed a deep-ultraviolet (UV) microscopy method that can rapidly assess T cell viability, activation state, and subtype-all without the need for fluorescent labels or cell destruction.

3 Apr 2026

Study reveals pearling mechanism behind mitochondrial DNA spacing

Mitochondria are often described as the cell's power plants, because they generate energy. To help them achieve this, mitochondria carry their own small genome called mitochondrial DNA (mtDNA).

2 Apr 2026

Lab gloves may inflate microplastics measurements in research studies

Nitrile and latex gloves that scientists wear while they are measuring microplastics may lead to a potential overestimation of the tiny pollutants, according to a University of Michigan study.

28 Mar 2026

New AI system maps gene expression across the whole body

Understanding gene expression within the body has been a boon for 21st century biology and therapeutics, but most discoveries that use these technologies only focus on one organ or one small area of tissue.

27 Mar 2026

NAC complex initiates early protein folding in human cells

In the earliest phase of creating human proteins, the protein complex NAC performs an essential task by starting the first steps towards folding proteins into their correct three-dimensional structures.

23 Mar 2026

Fluorescent imaging enables real-time observation of Toxoplasma gondii's growth

It infects nearly one-third of the global population, yet its microscopic size makes the Toxoplasma gondii parasite difficult for scientists to study.

23 Mar 2026

New approach tracks metabolic fingerprints of tuberculosis-infected human cells

Researchers from King's College London and the University of Surrey have developed a new technique to measure the content of individual human cells infected with bacteria that model tuberculosis – and it is already revealing biological changes that conventional analysis would miss.

18 Mar 2026