Histology & Microscopy

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Cryo-electron microscopy reveals how membrane microdomains respond to mechanical stress

Cell membranes play a crucial role in maintaining the integrity and functionality of cells. However, the mechanisms by which they perform these roles are not yet fully understood.

24 Jul 2024

Multiplexed STED nanoscopy technique reduces photobleaching and phototoxicity in live-cell imaging

A new publication from Opto-Electronic Advances; DOI 10.29026/oea.2024.240035 discusses multiplexed stimulated emission depletion nanoscopy for multi-color live-cell long-term imaging.

23 Jul 2024

New microscopy technique unveils dynamic structure of amyloid-beta

Amyloid-beta (A-beta) aggregates are tangles of proteins most notably associated with neurodegenerative diseases like Alzheimer's.

19 Jul 2024

Flu viruses can use a second entry pathway to infect cells

Most influenza viruses enter human or animal cells through specific pathways on the cells' surface. Researchers at the University of Zurich have now discovered that certain human flu viruses and avian flu viruses can also use a second entry pathway, a protein complex of the immune system, to infect cells.

18 Jul 2024

Optical metabolic imaging reveals how Toxoplasma infection changes host cell metabolism

Toxoplasma gondii is a parasite responsible for toxoplasmosis, a lifelong chronic infection prevalent in about 30% of the human population.

12 Jul 2024

Study reveals how DDM1 protein suppresses 'jumping genes' in plants

International joint research led by Akihisa Osakabe and Yoshimasa Takizawa of the University of Tokyo has clarified the molecular mechanisms in thale cresses (Arabidopsis thaliana) by which the DDM1 (Decreased in DNA Methylation 1) protein prevents the transcription of "jumping genes."

11 Jul 2024

Cryo-EM reveals structural dynamics of RNAP-DNA interactions during transcription initiation

Every living cell transcribes DNA into RNA. This process begins when an enzyme called RNA polymerase (RNAP) clamps onto DNA. Within a few hundred milliseconds, the DNA double helix unwinds to form a node known as the transcription bubble, so that one exposed DNA strand can be copied into a complementary RNA strand.

10 Jul 2024

New study reveals how RNA polymerase opens the transcription bubble in real time

Every living cell transcribes DNA into RNA. This process begins when an enzyme called RNA polymerase (RNAP) clamps onto DNA.

3 Jul 2024

High-resolution real-time imaging reveals early developmental processes in quail embryos

Researchers at The University of Queensland have for the first time captured images and video in real time of early embryonic development to understand more about congenital birth defects.

1 Jul 2024

New APIC method eliminates blurriness and distortion in microscopy

For hundreds of years, the clarity and magnification of microscopes were ultimately limited by the physical properties of their optical lenses.

28 Jun 2024

Innovative SRPFM technique enables ultra-sensitive force measurement at nanoscale in fluids

Groundbreaking research has revealed a new way to measure incredibly minute forces at the nanoscale in water, pushing the boundaries of what scientists know about the microscopic world.

24 Jun 2024

Synthetic cell mimics immune response via symmetry breaking

In a feat aimed at understanding how cells move and creating new ways to shuttle drugs through the body, scientists at Johns Hopkins Medicine say they have built a minimal synthetic cell that follows an external chemical cue and demonstrates a governing principle of biology called "symmetry breaking."

12 Jun 2024

Histology & Microscopy

Cryo-electron microscopy reveals how membrane microdomains respond to mechanical stress

Multiplexed STED nanoscopy technique reduces photobleaching and phototoxicity in live-cell imaging

New microscopy technique unveils dynamic structure of amyloid-beta

Flu viruses can use a second entry pathway to infect cells

Optical metabolic imaging reveals how Toxoplasma infection changes host cell metabolism

Study reveals how DDM1 protein suppresses 'jumping genes' in plants

Cryo-EM reveals structural dynamics of RNAP-DNA interactions during transcription initiation

New study reveals how RNA polymerase opens the transcription bubble in real time

High-resolution real-time imaging reveals early developmental processes in quail embryos

New APIC method eliminates blurriness and distortion in microscopy

Innovative SRPFM technique enables ultra-sensitive force measurement at nanoscale in fluids

Synthetic cell mimics immune response via symmetry breaking

Unveiling Pseudomonas aeruginosa's lung invasion tactics with human lung microtissues

Key protein orco crucial for ant olfactory neuron survival and social behavior

Novel CMOS sensor captures fast and subtle neural voltage fluctuations

Advanced imaging reveals hidden differences in T cell activation

Super-resolution microscopy offers high-resolution view of virus replication inside cells

Researchers decode spatial structure of prime editor

New ultrasound method reveals minute vascular structures using contrast agents

Advanced techniques reveal plectasin's velcro-like action against bacteria

E-Cigarettes and Ethanol: A forensic Perspective on Vaping

Understanding Consumer-Consented Data to Optimize Digital Health Programs

The Future is Wearable: Advancing Human Health Through Portable Spectroscopy

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