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Novel antibody-drug conjugate shows 29% response rate in rare blood cancer

Early study data shows a 29% overall response rate, the favorable safety profile in blastic plasmacytoid dendritic cell neoplasm (BPDCN)

8 Dec 2020

Degenerative process can be reversed by practicing regular aerobic exercise, shows study

Adipose tissue is not just a simple reservoir of energy for periods of food scarcity. It contributes significantly to regulation of the metabolism, releasing various molecules into the bloodstream, including microRNAs that modulate the expression of key genes in different parts of the organism, including the liver, pancreas, and muscles.

8 Dec 2020

Study compares effects of two omega-3s in older adults with obesity and chronic inflammation

The omega-3 fatty acids EPA and DHA work differently against chronic inflammation, according to the results of a small randomized study, suggesting each has its own important role to play in regulating the immune system.

8 Dec 2020

Higher degrees of necrosis are inked to poor survival in brain cancer patients

White blood cells are part of many immune system responses in the human body. New research shows that a specific type of those cells may cause brain cancer tissues to die – but that's not good news, according to researchers at Penn State College of Medicine and Penn State Cancer Institute.

8 Dec 2020

Phase I/IIA open-label study presents encouraging results on hard-to-treat AML subtypes

Novel menin-KMT2A inhibitor appears to be safe and well-tolerated. FLT3 inhibitor plus low-dose chemotherapy shows promising efficacy and safety. Results represent encouraging news on hard-to-treat AML subtypes.

7 Dec 2020

Study reveals low detection of SARS-CoV-2 on environmental surfaces across oncology settings

Researchers from Rutgers Cancer Institute of New Jersey, the state's only National Cancer Institute-designated Comprehensive Cancer Center, evaluated the frequency of SARS-CoV-2, the virus that causes COVID-19, on various environmental surfaces in outpatient and inpatient hematology/oncology settings located within Rutgers Cancer Institute and Robert Wood Johnson University Hospital, an RWJBarnabas Health facility.

7 Dec 2020

Study highlights previously unknown mechanisms involved in myeloma resistance

A group of researchers led by Maximillian Merz, MD, Assistant Professor of Oncology with the Myeloma team at Roswell Park Comprehensive Cancer Center, conducted the first prospective clinical trial investigating spatial heterogeneity in patients with either relapsed/refractory or newly diagnosed multiple myeloma.

7 Dec 2020

Researchers evaluate safety of novel therapy for patients with non-Hodgkin lymphoma

Roswell Park Comprehensive Cancer Center's Francisco J. Hernandez-Ilizaliturri, MD, along with a team of researchers from other institutions, has been investigating a novel therapy for patients with relapsed or refractory B-cell non-Hodgkin lymphoma.

7 Dec 2020

New article highlights health disparities, social determinants of health

The December issue of The American Journal of Gastroenterology is now available and features new clinical research across a wide range of gastroenterology and hepatology topics, including health disparities, colorectal cancer, cirrhosis, pediatric gastroenterology, the environmental impact of endoscopy, and more.

7 Dec 2020

Patients with atopic dermatitis more likely to have autoimmune diseases

In a recent study published in the British Journal of Dermatology, individuals with atopic dermatitis, or eczema, were more likely to also have various autoimmune diseases, especially those involving the skin, the gastrointestinal tract, or the connective tissue.

7 Dec 2020

Study: Caplacizumab not cost effective for treating thrombotic thrombocytopenic purpura

In a new study by Yale Cancer Center researchers, the drug caplacizumab is shown not to be cost-effective in treating thrombotic thrombocytopenic purpura (TTP) when added to the standard-of-care.

7 Dec 2020

Researchers analyze outcomes in patients with primary central nervous system lymphoma

Primary central nervous system lymphoma (PCNSL) is a type of cancer that develops in the brain and or spinal cord.

7 Dec 2020

Chemotherapy combined with blinatumomab increases survival for patients with Ph-negative B-ALL

A study led by The University of Texas MD Anderson Cancer Center showed that first-line treatment with a regimen of chemotherapy combined with the monoclonal antibody blinatumomab resulted in increased survival and achieved a high rate of measurable residual disease (MRD) negativity for patients who were newly diagnosed with a high-risk form of acute lymphoblastic leukemia (ALL) known as Philadelphia chromosome-negative B-cell ALL (Ph-negative B-ALL).

7 Dec 2020

Study finds CAR T cell therapy as effective as first-line treatment for high-risk large B-cell lymphoma

A study led by researchers at The University of Texas MD Anderson Cancer Center found that axi-cel, an autologous anti-CD19 chimeric antigen receptor (CAR) T cell therapy, is a safe and effective first-line therapy for patients with high-risk large B-cell lymphoma (LBCL), a group with an urgent need for new and effective treatments.

7 Dec 2020

COVID-19 crisis increases burden of dementia caregivers

Caregivers of people with dementia and milder forms of neurocognitive disorder bear a heavy burden.

7 Dec 2020

Researchers develop potential non-drug, non-surgical, long-acting therapy for glaucoma

Researchers have developed a potential new treatment for the eye disease glaucoma that could replace daily eye drops and surgery with a twice-a-year injection to control the buildup of pressure in the eye.

7 Dec 2020

Testing for tumor DNA can help predict risk of relapse after transplant in DLBCL patients

Many patients with diffuse large B-cell lymphoma (DLBCL) can be cured by a transplant using their own blood-forming stem cells, but as many as half eventually relapse.

7 Dec 2020

Kessler Foundation receives COVID-19 crisis funding to support spinal cord injury community

Kessler Foundation received a $10,000 grant from the Craig H. Neilsen Foundation's crisis funding to support the spinal cord injury (SCI) community and critical research amid the COVID-19 pandemic.

7 Dec 2020

Henry Ford and United Outstanding Physicians join hands to enhance cancer care

Henry Ford Cancer Institute and United Outstanding Physicians, a physician organization comprising nearly 1,000 independent private practice physicians across Southeast Michigan, have come together to enhance cancer care and make navigating the cancer journey easier for their patients.

7 Dec 2020

Research uncovers novel anti-craving mechanism to treat cocaine relapse

Cocaine continues to be one of the most commonly abused illicit drugs in the United States. Pre-clinical literature suggests that targeting glucagon-like peptide-1 receptors (GLP-1Rs) in the brain may represent a novel approach to treating cocaine use disorder.

7 Dec 2020

Medical Condition News

Novel antibody-drug conjugate shows 29% response rate in rare blood cancer

Degenerative process can be reversed by practicing regular aerobic exercise, shows study

Study compares effects of two omega-3s in older adults with obesity and chronic inflammation

Higher degrees of necrosis are inked to poor survival in brain cancer patients

Phase I/IIA open-label study presents encouraging results on hard-to-treat AML subtypes

Study reveals low detection of SARS-CoV-2 on environmental surfaces across oncology settings

Study highlights previously unknown mechanisms involved in myeloma resistance

Researchers evaluate safety of novel therapy for patients with non-Hodgkin lymphoma

New article highlights health disparities, social determinants of health

Patients with atopic dermatitis more likely to have autoimmune diseases

Study: Caplacizumab not cost effective for treating thrombotic thrombocytopenic purpura

Researchers analyze outcomes in patients with primary central nervous system lymphoma

Chemotherapy combined with blinatumomab increases survival for patients with Ph-negative B-ALL

Study finds CAR T cell therapy as effective as first-line treatment for high-risk large B-cell lymphoma

COVID-19 crisis increases burden of dementia caregivers

Researchers develop potential non-drug, non-surgical, long-acting therapy for glaucoma

Testing for tumor DNA can help predict risk of relapse after transplant in DLBCL patients

Kessler Foundation receives COVID-19 crisis funding to support spinal cord injury community

Henry Ford and United Outstanding Physicians join hands to enhance cancer care

Research uncovers novel anti-craving mechanism to treat cocaine relapse

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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