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Cognitive outcomes in survivors of childhood cancers have been largely understudied

In a new study led by Yale Cancer Center, researchers report many survivors of childhood cancers receive systemic therapies associated with cognitive effects and chronic health conditions that may impact long-term cognitive outcomes with downstream effects on education, employment, and income.

23 Apr 2021

New method helps map the specialized diversity and spatial location of cells within a tissue or tumor

Not all cancer cells within a tumor are created equal; nor do all immune cells (or all liver or brain cells) in your body have the same job. Much of their function depends on their location.

23 Apr 2021

C-Path opens access to D-RSC database to accelerate therapy development for DMD

Critical Path Institute announced today that it will open access to the Duchenne Regulatory Science Consortium (D-RSC) database to qualified researchers, through its Rare Disease Cures Accelerator, Data and Analytics Platform.

22 Apr 2021

Clinical trial examines metabolic effects of natural compound NMN in people

A natural compound previously demonstrated to counteract aspects of aging and improve metabolic health in mice has clinically relevant effects in people, according to new research at Washington University School of Medicine in St. Louis.

22 Apr 2021

Increased use of tourniquets has improved patient survival in Los Angeles County

Uncontrolled bleeding continues to be one of the most common causes of preventable death from a traumatic injury.

22 Apr 2021

Changing the treatment paradigm for ‘cold’ tumors

Not all cancerous tumors are created equal. Some tumors, known as "hot" tumors, show signs of inflammation, which means they are infiltrated with T cells working to fight the cancer. Those tumors are easier to treat, as immunotherapy drugs can then amp up the immune response.

22 Apr 2021

Experimental drug reverses key symptoms of Alzheimer's disease in mice

Researchers at Albert Einstein College of Medicine have designed an experimental drug that reversed key symptoms of Alzheimer's disease in mice.

22 Apr 2021

Race, neighborhood poverty, insurance associated with higher mortality in people under 40 with cancer

Being Black or Hispanic, living in high-poverty neighborhoods, and having Medicaid or no insurance coverage are associated with higher mortality in men and women under 40 with cancer, a review by UT Southwestern Medical Center researchers found.

22 Apr 2021

Research data may provide new treatment options for hormone-dependent breast cancer

Notch proteins are key regulators of growth and differentiation of both normal and cancer cells. Researchers in Turku, Finland, have now demonstrated that the activities of distinct Notch family members are modified differently by phosphorylation.

22 Apr 2021

Study identifies risk factors for delirium among hospitalized patients in Zambia

Severity of illness, history of stroke, and being divorced or widowed were independently predictive of delirium in hospitalized patients in Zambia, according to a study published in PLOS ONE.

22 Apr 2021

FDA approves immunotherapy for treating patients with dMMR endometrial cancer

Today, the U.S. Food and Drug Administration granted accelerated approval to Jemperli (dostarlimab) for treating patients with recurrent or advanced endometrial cancer that has progressed on or following prior treatment with a platinum-containing chemotherapy and whose cancers have a specific genetic feature known as dMMR (which contain abnormalities that affect the proper repair of DNA inside the cell), as determined by an FDA-approved test.

22 Apr 2021

FDA approves clinical trials to test the safety of cancer-detection technology

The U.S. Food and Drug Administration has approved human clinical trials to test the safety of cancer-detection technology developed at Case Western Reserve University: a tumor-targeting contrast agent that accurately detects aggressive prostate cancer in a magnetic resonance imaging (MRI) scan.

22 Apr 2021

Drugs can help prevent progression of cardiac hypertrophy in hemodialysis patients

Patients with chronic kidney dysfunction frequently develop thickening of the heart muscle, so-called left ventricular hypertrophy. This is particularly pronounced in patients who are in the late stage of renal dysfunction, that is to say those requiring renal replacement therapy such as hemodialysis.

22 Apr 2021

NCCS starts clinical trial to examine the use of TCM in countering cancer-related symptoms

The National Cancer Centre Singapore has started a clinical trial to examine the use of Traditional Chinese Medicine in countering cancer-related symptoms or side effects of cancer treatment to improve cancer survivors' quality of life.

22 Apr 2021

Mental health disorders increased sharply among Americans during first 9 months of COVID-19 pandemic

Confirming anecdotal evidence that the spread of the coronavirus has strained Americans' mental health, Boston College researchers found reports of anxiety increased to 50 percent and depression to 44 percent by November, 2020 - rates six times higher than 2019 - according to a new report in the journal Translational Behavioral Medicine.

22 Apr 2021

UTHSC researchers receive $1.99 million to advance understanding of diabetes pathophysiology

The National Institute of Diabetes and Digestive and Kidney Diseases recently awarded a team of UTHSC researchers $1.99 million for their work to advance understanding of the pathophysiology of prediabetes, diabetes, and related complications.

22 Apr 2021

Impact of proposed law would increase regulatory oversight of certain diagnostic tests

Legislation currently under consideration in the U.S. Congress would increase regulatory oversight of certain diagnostic tests, and a new study by researchers at Massachusetts General Hospital (MGH) and colleagues from several other institutions demonstrates that its potential impact will depend on key details in the bill's final language.

22 Apr 2021

Medical Condition News

Cognitive outcomes in survivors of childhood cancers have been largely understudied

New method helps map the specialized diversity and spatial location of cells within a tissue or tumor

C-Path opens access to D-RSC database to accelerate therapy development for DMD

Clinical trial examines metabolic effects of natural compound NMN in people

Increased use of tourniquets has improved patient survival in Los Angeles County

Changing the treatment paradigm for ‘cold’ tumors

Experimental drug reverses key symptoms of Alzheimer's disease in mice

Race, neighborhood poverty, insurance associated with higher mortality in people under 40 with cancer

Research data may provide new treatment options for hormone-dependent breast cancer

Study identifies risk factors for delirium among hospitalized patients in Zambia

FDA approves immunotherapy for treating patients with dMMR endometrial cancer

FDA approves clinical trials to test the safety of cancer-detection technology

Drugs can help prevent progression of cardiac hypertrophy in hemodialysis patients

NCCS starts clinical trial to examine the use of TCM in countering cancer-related symptoms

Mental health disorders increased sharply among Americans during first 9 months of COVID-19 pandemic

UTHSC researchers receive $1.99 million to advance understanding of diabetes pathophysiology

Impact of proposed law would increase regulatory oversight of certain diagnostic tests

Researchers examine if a naturally occurring protein can be used to prevent sight loss from glaucoma

Study describes “cocktail party effect” in people with hearing loss

People with multiple sclerosis experience subtle language impairments, study shows

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

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