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Targeting RNA splicing can activate antiviral immune pathways in triple negative breast cancers

Researchers at Baylor College of Medicine have discovered how therapeutics targeting RNA splicing can activate antiviral immune pathways in triple negative breast cancers (TNBC) to trigger tumor cell death and signal the body's immune response.

15 Jan 2021

Newly discovered biochemical pathway can protect cells from ferroptosis

The hallmarks of cancer include rapid cell-reproduction and metabolic activity. But these processes also lead to increased cellular stress and oxidation, and the risk of cell death.

15 Jan 2021

iTHRIV announces recipients of health research pilot projects

The Clinical and Translational Science Award (CTSA) hub partnership between Virginia Tech, the University of Virginia, Carilion Clinic, and Inova Health System has awarded $200,000 in funding to five research projects through the Pilot Translational and Clinical Studies Program. Multi-institutional teams of scientists, physicians, and engineers will study Parkinson's disease, celiac disease, pediatric heart transplant, pediatric telemedicine, and epilepsy.

15 Jan 2021

New study can help determine effectiveness of chemotherapy in patients with bladder cancer

In patients with bladder cancer, chemotherapy effectiveness is partially determined by the body's immune system response to the malignancy. This is the conclusion of research conducted by a team of scientists from Charité - Universitätsmedizin Berlin and the Berlin Institute of Health.

15 Jan 2021

Study offers a differentiated patient-specific solution in minimal residual disease testing

Exact Sciences Corp. today announced that it has acquired a worldwide exclusive license to the proprietary TARDIS technology from the Translational Genomics Research Institute (TGen), an affiliate of City of Hope.

15 Jan 2021

Certain oral pathogens are more prevalent in esophageal cancer patients

Researchers led by Tokyo Medical and Dental University (TMDU) find that certain oral pathogens are more prevalent in esophageal cancer patients, and could be used as a novel diagnostic tool.

14 Jan 2021

Specific brain neurons could provide a target for treating sleep-related disorders

We laugh when we see Homer Simpson falling asleep while driving, while in church, and while even operating the nuclear reactor. In reality though, narcolepsy, cataplexy, and rapid eye movement (REM) sleep behavior disorder are all serious sleep-related illnesses.

14 Jan 2021

New cellular pathway limits growth and spread of brain tumors

Researchers at McGill University have identified a new cellular pathway that limits the growth and spread of brain tumors by controlling the recycling of cell surface receptor proteins.

14 Jan 2021

Study compares the odds of major depression classification based on SCID, CIDI, and MINI

Three previous meta-analyses reported that, compared to the Structured Clinical Interview for the DSM (SCID), alternative reference standards, primarily the Composite International Diagnostic Interview (CIDI) and the Mini International Neuropsychiatric Interview (MINI), tended to misclassify major depression status, when controlling for depression symptom severity. However, there was an important lack of precision in the results.

14 Jan 2021

Researchers demonstrate great potential for blood test to detect, monitor Alzheimer's disease

In three recent publications in Molecular Psychiatry, Brain and JAMA Neurology researchers from the University of Gothenburg provide convincing evidence that an in-house developed blood test for Alzheimer's disease can detect the disease early and track its course, which has major implications for a potential use in clinical practice and treatment trials.

14 Jan 2021

UH researcher working to identify potential new therapeutic targets for kidney disease

Among the primary forms of kidney disease, focal segmental glomerulosclerosis (FSGS) is the most common and is marked by high circulating levels of the suPAR protein (soluble urokinase-type plasminogen activator receptor).

13 Jan 2021

MIND and Mediterranean diets correlated with later onset of Parkinson's disease

A new study from UBC researchers suggests a strong correlation between following the MIND and Mediterranean diets and later onset of Parkinson's disease (PD).

13 Jan 2021

Researchers receive $5.1 million to expand clinical trial of drug to prevent ARDS in COVID-19 patients

Researchers evaluating whether an investigational oral drug, vadadustat, can help prevent acute respiratory distress s to expand the Phase II clinical trial at The University of Texas Health Science Center at HoustonQ.

13 Jan 2021

Study reveals cardiac protein as a new target for different types of heart disease

Like a failing fuel pump that causes a loss of engine power in a car, a diseased heart can take a serious toll on the body's performance. For some patients, tasks like walking up a flight of stairs or walking across a room eventually turn into exhausting endeavors.

13 Jan 2021

Researchers explore link between work addiction risk and health-related outcomes

Workaholism or work addiction risk is a growing public health concern that can lead to many negative mental and physical health outcomes such as depression, anxiety or sleep disorder.

13 Jan 2021

Drug found to be safe and effective for treating patients with obesity and type 2 diabetes

A new study confirms that treatment with Bimagrumab, an antibody that blocks activin type II receptors and stimulates skeletal muscle growth, is safe and effective for treating excess adiposity and metabolic disturbances of adult patients with obesity and type 2 diabetes.

13 Jan 2021

Scientists identify key enzyme as driver of autoimmune blistering diseases

The Granzyme B (GzmB) enzyme, which accumulates in certain tissues as we age, has been identified as a driver of itchy and sometimes life-threatening autoimmune conditions known as pemphigoid diseases (PDs), which cause blistering and skin erosion below the skin's surface.

13 Jan 2021

Medical Condition News

Targeting RNA splicing can activate antiviral immune pathways in triple negative breast cancers

Newly discovered biochemical pathway can protect cells from ferroptosis

iTHRIV announces recipients of health research pilot projects

New study can help determine effectiveness of chemotherapy in patients with bladder cancer

Study offers a differentiated patient-specific solution in minimal residual disease testing

Certain oral pathogens are more prevalent in esophageal cancer patients

Specific brain neurons could provide a target for treating sleep-related disorders

New cellular pathway limits growth and spread of brain tumors

Study compares the odds of major depression classification based on SCID, CIDI, and MINI

Researchers demonstrate great potential for blood test to detect, monitor Alzheimer's disease

UH researcher working to identify potential new therapeutic targets for kidney disease

MIND and Mediterranean diets correlated with later onset of Parkinson's disease

Researchers receive $5.1 million to expand clinical trial of drug to prevent ARDS in COVID-19 patients

Study reveals cardiac protein as a new target for different types of heart disease

Researchers explore link between work addiction risk and health-related outcomes

Drug found to be safe and effective for treating patients with obesity and type 2 diabetes

Scientists identify key enzyme as driver of autoimmune blistering diseases

COVID-19 survivors can show persistent symptoms six months after recovery, study finds

Researchers use urine test to identify and verify a patient's type of asthma

Recurring glioblastomas with very few mutations are far more vulnerable to immunotherapies

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

Obesity, GLP-1s, and metabolic care

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