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MicroRNA dysregulation has critical impacts on development, inflammation and cancer development

Oncotarget Volume 11, Issue 10 reported that dysregulation of noncoding micro RNA molecules has been associated with immune cell activation in the context of Helicobacter pylori-induced gastric inflammation as well as carcinogenesis, but also with downregulation of mismatch repair genes, and may interfere with immune checkpoint proteins that lead to the overexpression of antigens on gastric tumor cells.

13 Mar 2020

Characterization of DNAm status of MMPs and TIMPs in atheromatous plaques

Oncotarget Volume 11, Issue 10 reported that the statistically associated Cp G sites were analyzed in blood samples from two separate atherothrombotic stroke cohorts, ischemic stroke-cohort 1: 37 atherothrombotic patients and 6 controls, ischemic stroke-cohort 2: 80 atherothrombotic patients and 184 controls.

13 Mar 2020

Tooth-enamel protein discovered in the eyes of people with dry AMD

A protein that normally deposits mineralized calcium in tooth enamel may also be responsible for calcium deposits in the back of the eye in people with dry age-related macular degeneration, according to a study from researchers at the National Eye Institute.

13 Mar 2020

Study: Evidence clearly favors tax on sugary drinks

New Zealand should follow the UK and more than 30 other countries in introducing a tax on sugary drinks to tackle obesity and reduce deaths from chronic diseases, leading researchers say.

13 Mar 2020

Preserving kidney function in patients with diabetic kidney disease

Diabetic kidney disease, which affects between 20 to 40 percent of people with diabetes, is a serious complication that can ultimately lead to end-stage kidney disease--a life-threatening condition that requires either dialysis or kidney transplant.

13 Mar 2020

UK study highlights importance of breathing tests in the assessment of COPD

A UK study of patients participating in low-dose CT lung cancer screening highlights the importance of spirometry (breathing tests) in the assessment of possible chronic obstructive pulmonary disease (COPD), and demonstrates that over-reliance on radiological changes alone may result in detection of clinically insignificant disease.

13 Mar 2020

NTHU research team develops new treatment for Parkinson’s disease

Ultrasound is widely used for conducting physical examinations, and plans are underway for expanding its application to the treatment of Parkinson's disease, dementia, and diabetes.

12 Mar 2020

Protective brain-cell housekeeping mechanism may also be involved in regulating sleep

An important biological mechanism that is thought to protect brain cells from neurodegenerative diseases such as Alzheimer's and Parkinson's may also be involved in regulating sleep, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

12 Mar 2020

Mayo Clinic study uncovers stem cell-activated mechanisms of healing after heart attack

Mayo Clinic researchers have uncovered stem cell-activated mechanisms of healing after a heart attack. Stem cells restored cardiac muscle back to its condition before the heart attack, in turn providing a blueprint of how stem cells may work.

12 Mar 2020

Aspergillus molds induce asthma by first attacking the lung's protective barrier

University of Wisconsin-Madison researchers have identified a new way that common Aspergillus molds can induce asthma, by first attacking the protective tissue barrier deep in the lungs.

12 Mar 2020

New recommendations for evaluation of bladder and bowel dysfunction after spinal cord injury

Among the many challenges to independence and quality of life after spinal cord injury, two complications have emerged as top priorities for researchers - neurogenic bowel and neurogenic bladder.

12 Mar 2020

Study sheds new light on the neurobiology of starvation in patients with anorexia nervosa

Researchers at University of California San Diego School of Medicine have discovered differences in brain circuitry that contribute to starvation and weight loss in people with anorexia nervosa

12 Mar 2020

Vaccinating both boys and girls can help eliminate HPV infections

The human papillomavirus causes, amongst other diseases, cancer of the cervix and oropharynx. A Swedish-Finnish study published in The Journal of Infectious Diseases now shows that the most oncogenic HPV types can be eliminated, but only if both girls and boys are vaccinated.

12 Mar 2020

Fruit flies provide insight on ACOX1-related neurodegenerative disorders

A study led by researchers at Baylor College of Medicine reports that a hyperactive variant of enzyme ACOX1 produces elevated levels of toxic reactive oxygen species (ROS) and causes a previously unidentified late-onset neurodegenerative disorder.

12 Mar 2020

Low-dose aspirin linked to lower risk of hepatocellular carcinoma and liver-related mortality

Among adults at high risk of liver cancer, those who took low-dose aspirin were less likely to develop the disease or to die from liver-related causes.

12 Mar 2020

No evidence of a link between surgery with anesthesia and Alzheimer's disease

Older adults who have surgery with general anesthesia may experience a modest acceleration of cognitive decline, even years later. But there's no evidence of a link to Alzheimer's disease, according to new research from Mayo Clinic.

12 Mar 2020

Scientists identify genes involved in the development of diabetic kidney disease

By analyzing samples from hundreds of Finns with diabetes, scientists have identified genes, and the proteins they encode, that could be involved in the development of diabetic kidney disease.

12 Mar 2020

Researchers uncover clues to how statins kill cancer cells

More than 35 million Americans take statin drugs daily to lower their blood cholesterol levels. Now, in experiments with human cells in the laboratory, researchers at Johns Hopkins Medicine have added to growing evidence that the ubiquitous drug may kill cancer cells and have uncovered clues to how they do it.

12 Mar 2020

Air pollution exposure takes a heavy toll on gut bacteria, boosting risk of chronic illnesses

Breathing dirty air takes a heavy toll on gut bacteria, boosting risk of obesity, diabetes, gastrointestinal disorders and other chronic illnesses, new University of Colorado Boulder research suggests.

11 Mar 2020

Bowel cancer on the up in England’s young adults

A new study published in March 2020, in the British Journal of Surgery (BJS), shows that the number of young adults with bowel cancer is rising at an alarming rate in England.

11 Mar 2020

Medical Condition News

MicroRNA dysregulation has critical impacts on development, inflammation and cancer development

Characterization of DNAm status of MMPs and TIMPs in atheromatous plaques

Tooth-enamel protein discovered in the eyes of people with dry AMD

Study: Evidence clearly favors tax on sugary drinks

Preserving kidney function in patients with diabetic kidney disease

UK study highlights importance of breathing tests in the assessment of COPD

NTHU research team develops new treatment for Parkinson’s disease

Protective brain-cell housekeeping mechanism may also be involved in regulating sleep

Mayo Clinic study uncovers stem cell-activated mechanisms of healing after heart attack

Aspergillus molds induce asthma by first attacking the lung's protective barrier

New recommendations for evaluation of bladder and bowel dysfunction after spinal cord injury

Study sheds new light on the neurobiology of starvation in patients with anorexia nervosa

Vaccinating both boys and girls can help eliminate HPV infections

Fruit flies provide insight on ACOX1-related neurodegenerative disorders

Low-dose aspirin linked to lower risk of hepatocellular carcinoma and liver-related mortality

No evidence of a link between surgery with anesthesia and Alzheimer's disease

Scientists identify genes involved in the development of diabetic kidney disease

Researchers uncover clues to how statins kill cancer cells

Air pollution exposure takes a heavy toll on gut bacteria, boosting risk of chronic illnesses

Bowel cancer on the up in England’s young adults

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

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