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Link between ALS and Alzheimer's disease can help advance the search for new therapies

On the surface, amyotrophic lateral sclerosis (ALS) and Alzheimer's disease share two commonalities: Both are progressively debilitating neurodegenerative conditions--meaning symptoms get worse--and, at least for now, neither has an effective treatment, let alone a cure.

16 Jun 2020

Early genetic rescue may be a potential therapy in autism spectrum disorder

A mouse study by Craig Powell, M.D., Ph.D., and colleagues suggests that early genetic rescue may be a potential therapy in autism spectrum disorder or ASD.

16 Jun 2020

Micro-dystrophin gene therapy can improve outcomes in children with Duchenne muscular dystrophy

Researchers from Nationwide Children's Hospital have published in JAMA Neurology results from the first four patients treated in the first clinical trial of systemic delivery of micro-dystrophin gene therapy in children with Duchenne muscular dystrophy (DMD) - and initial findings suggest that the therapy can provide functional improvement that is greater than that observed under the standard of care.

16 Jun 2020

Oxytocin study may help treat a variety of psychiatric conditions

During the pandemic lockdown, as couples have been forced to spend days and weeks in one another's company, some have found their love renewed while others are on their way to divorce court.

16 Jun 2020

Millimeter-thick cell-laden hydrogel fiber helps control blood glucose in diabetic mice

Type 1 diabetes mellitus results from an irreversible autoimmune destruction of insulin-producing pancreatic β-cells requiring life-long substitution of insulin.

15 Jun 2020

Breakthrough drug significantly delays onset of type 1 diabetes, study finds

Emily Sims, M.D. today shared new findings that a breakthrough drug significantly delays the onset of type 1 diabetes (T1D).

15 Jun 2020

Inhaled steroids reduce ACE2 expression in COPD lungs

A new study by scientists at Imperial College London, University of Newcastle and Prokarium, and published on the preprint server bioRxiv* in June 2020 examines the role played by inhaled corticosteroids (ICS) in the risk of acquisition of COVID-19 infection by COPD patients.

15 Jun 2020

Study delves into causes of post-trauma nightmare occurrences

It's been estimated that up to 88% of survivors of rape or molestation suffer from persistent nightmares that can occur multiple times per week, seemingly at random.

15 Jun 2020

Genetic marker may predispose African Americans to cardiac complications from COVID-19

Nearly one out of every 10 African Americans has a genetic variant that puts them inherently at an increased risk for ventricular arrhythmias and sudden cardiac death.

15 Jun 2020

Irregular circadian rhythm in older adults associated with increased risk of Parkinson's disease

Older men who have a weak or irregular circadian rhythm guiding their daily cycles of rest and activity are more likely to later develop Parkinson's disease, according to a new study by scientists at the UC San Francisco Weill Institute for Neurosciences who analyzed 11 years of data for nearly 3,000 independently living older men.

15 Jun 2020

Common cholesterol-lowering drug linked to improvement in gut microbiota

There is a clear link between improved gut microbiota and one of our most common cholesterol-lowering drug groups: statins.

15 Jun 2020

GLP-1-based medicine for diabetic patients does not cause pancreatitis

About 50,000 Danish diabetic patients are treated with GLP-1-based medicine. GLP-1 is a hormone that reduces the blood sugar and inhibits the appetite, and it is a frequent treatment for type 2 diabetes and obesity.

15 Jun 2020

Nearly $19 million awarded for longitudinal study of brain aging and cognitive change

Researchers at University of California San Diego School of Medicine, with colleagues at Boston University and elsewhere, will receive almost $19 million over five years to launch the fourth phase of the Vietnam Era Twin Study of Aging. Funded by the National Institute on Aging, the grant will support ongoing research, including large-scale behavioral genetics studies, of cognition, aging and the risk for mild cognitive impairment (MCI) and Alzheimer's disease (AD).

15 Jun 2020

New UNLV Center offers hope for people suffering from neurological diseases

The UNLV department of brain health has formally launched the Chambers-Grundy Center for Transformative Neuroscience, offering hope through scientific discovery for patients who are suffering from Alzheimer's, dementia and other brain and neurological diseases.

15 Jun 2020

Deep vein thrombosis common in patients with moderate to severe COVID-19

In their paper available on the medRxiv preprint server, researchers from Russia showed that patients with moderate and severe coronavirus disease (COVID-19) have a high incidence of deep vein thrombosis – indicating that they may necessitate an early administration of anticoagulation therapy as a part of their treatment regimen.

15 Jun 2020