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Breast cancer cells can reprogram natural killer cells to aid in metastasis

Natural killer cells, a type of immune cell, are known to limit metastasis by inducing the death of cancer cells. But metastases still form in patients, so there must be ways for cancer cells to escape.

9 Jul 2020

Groundbreaking study identifies unique lung cells that may drive pulmonary fibrosis

A groundbreaking study published today and led by the Translational Genomics Research Institute, an affiliate of City of Hope, identifies unique lung cells that may drive Idiopathic Pulmonary Fibrosis, a deadly lung disease that affects hundreds of thousands of Americans, and for which there is no cure.

9 Jul 2020

ACTIONED consortium aims to transform future treatment of colorectal cancer patients

The Precision Medicine Centre of Excellence (PMC) at Queen's is leading a ground-breaking collaboration with the world's largest biotech company Roche, and Artificial Intelligence (AI) specialist, Sonrai Analytics.

9 Jul 2020

Researchers identify factor that regulates the abnormal growth of heart

The human heart is like a sponge, able to expand and grow, increasing its capacity to take up blood. In theory, an enlarged heart can also squeeze out more blood, with more power, than an average-sized heart. But in reality, for most people, this growth - known as cardiac hypertrophy - is abnormal and signals trouble.

9 Jul 2020

Health care providers should increase access to nature, indicates study

While access to nature is an established social determinant of health with clear benefits to physical, mental, and social health, it does not receive as must attention by health care providers or health systems as other social concerns, according to a new piece by a Penn Medicine physician published today in the American Journal of Preventive Medicine.

9 Jul 2020

New nanoconjugate blocks dissemination of tumor cells in animal models of acute myeloid leukemia

The nanoparticle targets only leukemic cells and therefore would reduce the severe adverse effects of current treatments.

9 Jul 2020

People with arthritis report worsening symptoms during Covid-19 lockdown

People with arthritis experienced a ‘roller coaster’ of emotions and saw their symptoms worsen during the Covid-19 lockdown – according to research from the University of East Anglia.

9 Jul 2020

New grant added to Stroke Foundation’s research program

A new research grant, focused on stopping stroke before it happens, has been added to the Stroke Foundation’s well-established research program.

9 Jul 2020

UniSA researchers pioneer new method to more accurately diagnose Parkinson’s disease

University of South Australia researchers are pioneering a new method to more accurately diagnose Parkinson’s disease, a neurodegenerative brain disorder which affects around 70,000 Australians, resulting in a loss of control of body movements.

9 Jul 2020

siRNA therapeutics can reduce off-target side effects of anticancer drugs

Small interfering RNA (siRNA) has shown tremendous potential for treating human diseases in the past decades.

9 Jul 2020

Law enforcement and community partnership screen children for PTSD

The Child Trauma Response Team, innovative policy, and community-based organization partnership demonstrated success at screening and treating children for post-traumatic stress disorder (PTSD) immediately following incidents of intimate partner violence, according to a Rutgers-led study published in the Journal of Interpersonal Violence.

9 Jul 2020

PRMT5 inhibitors can help treat advanced melanoma

Scientists at Sanford Burnham Prebys Medical Discovery Institute have demonstrated the therapeutic potential of PRMT5 inhibitors to sensitize unresponsive melanoma to immune checkpoint therapy.

9 Jul 2020

New research shows promise for treating neuropsychiatric diseases

When trying to complete a task we are constantly bombarded by distracting stimuli. How does the brain filter out these distractions and enable us to focus on the task at hand?

9 Jul 2020

Study provides evidence on non-invasive diagnostic procedures for people with suspected CHD

The German Institute for Quality and Efficiency in Health Care (IQWiG) used an evidence map to investigate to what extent informative evidence exists on the benefit and harm of the diagnostic procedures "non-invasive computed tomography angiography" (CTA) and "stress MRI" in people with suspected coronary heart disease (CHD).

9 Jul 2020

Breast cancer simulation models can guide screening recommendations for women

Chest radiation is used to treat children with Hodgkin and non-Hodgkin lymphoma as well as lung metastases in various solid tumors.

9 Jul 2020

Researchers to create AI-based pill to precisely diagnose gastrointestinal cancers

A team led by University of Saskatchewan (USask) researcher Khan Wahid has been awarded $250,000 from the federal New Frontiers in Research Fund to create a new pill-sized capsule that uses artificial intelligence (AI)-enabled sensing to diagnose gastrointestinal cancers and bleeding earlier and more precisely than is currently possible.

9 Jul 2020

New research can help overcome challenges in diabetes research

Scientists focused on finding better treatments or cures for types 1 or 2 diabetes are painfully aware of current limitations, including having to use animal tissue in studies that often don't translate to human trials.

9 Jul 2020

Experimental drug for rare ALS shows promise in early clinical trial

An experimental drug for a rare, inherited form of amyotrophic lateral sclerosis (ALS) has shown promise in a phase 1/phase 2 clinical trial conducted at Washington University School of Medicine in St. Louis, Massachusetts General Hospital in Boston and other sites around the world and sponsored by the pharmaceutical company Biogen Inc.

8 Jul 2020

New method helps pinpoint new potential therapeutic targets for lupus

A team of researchers from Children's Hospital of Philadelphia (CHOP) used a new method of pinpointing potential disease-causing changes in the genome to identify two new potential therapeutic targets for lupus, while also paving the way for more accurately identifying disease-causing variations in other autoimmune disorders.

8 Jul 2020

Blocking tumor-promoting protein could bolster immunotherapy's effectiveness, study suggests

While immunotherapy -- a form of treatment that uses the body's immune system to recognize, attack and kill tumor cells -- has given hope to people across the globe, it fails in a significant proportion of cancer patients.

8 Jul 2020